PDB entry 6pvm

View 6pvm on RCSB PDB site
Description: cryo-em structure of mouse trpv3 in putative sensitized state at 42 degrees celsius
Deposited on 2019-07-21, released 2019-10-23
The last revision was dated 2019-12-04, with a file datestamp of 2019-11-29.
Experiment type: EM
Resolution: 4.5 Å
R-factor: N/A
AEROSPACI score: 0.02 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Transient receptor potential cation channel subfamily V member 3
    Species: Mus musculus [TaxId:10090]
    Gene: Trpv3
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Transient receptor potential cation channel subfamily V member 3
    Species: Mus musculus [TaxId:10090]
    Gene: Trpv3
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Transient receptor potential cation channel subfamily V member 3
    Species: Mus musculus [TaxId:10090]
    Gene: Trpv3
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Transient receptor potential cation channel subfamily V member 3
    Species: Mus musculus [TaxId:10090]
    Gene: Trpv3
    Database cross-references and differences (RAF-indexed):
  • Heterogens: NA

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6pvmA (A:)
mnahskemaplmgkrttapggnpvvltekrpadltptkksahffleiegfepnptvtkts
ppifskpmdsnirqclsgncddmdspqspqddvtetpsnpnspsanlakeeqrqkkkrlk
krifaavsegcveelrellqdlqdlcrrrrgldvpdflmhkltasdtgktclmkallnin
pntkeivrillafaeendildrfinaeyteeayegqtalniaierrqgditavliaagad
vnahakgvffnpkyqhegfyfgetplalaactnqpeivqllmeneqtditsqdsrgnnil
halvtvaedfktqndfvkrmydmillrsgnweletmrnndgltplqlaakmgkaeilkyi
lsreikekplrslsrkftdwaygpvssslydltnvdtttdnsvleiivyntnidnrheml
tleplhtllhtkwkkfakymfflsfcfyffynitltlvsyyrprededlphplalthkms
wlqllgrmfvliwatcisvkegiaifllrpsdlqsilsdawfhfvffvqavlvilsvfly
lfaykeylaclvlamalgwanmlyytrgfqsmgmysvmiqkvilhdvlkflfvyilfllg
fgvalasliekcskdkkdcssygsfsdavlelfkltiglgdlniqqnstypilflfllit
yviltfvlllnmlialmgetvenvskeseriwrlqrartilefekmlpewlrsrfrmgel
ckvadedfrlclrinevkwtewkthvsflnedpgpirrtadlnkiqdssrsnskttlyaf
deldefpetsvlvprgsaaawshpqfek

    Sequence, based on observed residues (ATOM records):
    >6pvmA (A:)
kkkrlkkrifaavsegcveelrellqdlqdlcrrrrgldvpdflmhkltasdtgktclmk
allninpntkeivrillafaeendildrfinaeyteeayegqtalniaierrqgditavl
iaagadvnahakgvffnpkyqhegfyfgetplalaactnqpeivqllmeneqtditsqds
rgnnilhalvtvaedfktqndfvkrmydmillrsgnweletmrnndgltplqlaakmgka
eilkyilsreikekplrslsrkftdwaygpvssslydltnvdtttdnsvleiivyntnid
nrhemltleplhtllhtkwkkfakymfflsfcfyffynitltlvsyyrprededlphpla
lthkmswlqllgrmfvliwatcisvkegiaifllrpsdlqsilsdawfhfvffvqavlvi
lsvflylfaykeylaclvlamalgwanmlyytrgfqsmgmysvmiqkvilhdvlkflfvy
ilfllgfgvalasliekcskdkkdcssygsfsdavlelfkltiglgdlniqqnstypilf
lfllityviltfvlllnmlialmgetvenvskeseriwrlqrartilefekmlpewlrsr
frmgelckvadedfrlclrinevkwtewkthvsflnedpgpirr

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6pvmB (B:)
mnahskemaplmgkrttapggnpvvltekrpadltptkksahffleiegfepnptvtkts
ppifskpmdsnirqclsgncddmdspqspqddvtetpsnpnspsanlakeeqrqkkkrlk
krifaavsegcveelrellqdlqdlcrrrrgldvpdflmhkltasdtgktclmkallnin
pntkeivrillafaeendildrfinaeyteeayegqtalniaierrqgditavliaagad
vnahakgvffnpkyqhegfyfgetplalaactnqpeivqllmeneqtditsqdsrgnnil
halvtvaedfktqndfvkrmydmillrsgnweletmrnndgltplqlaakmgkaeilkyi
lsreikekplrslsrkftdwaygpvssslydltnvdtttdnsvleiivyntnidnrheml
tleplhtllhtkwkkfakymfflsfcfyffynitltlvsyyrprededlphplalthkms
wlqllgrmfvliwatcisvkegiaifllrpsdlqsilsdawfhfvffvqavlvilsvfly
lfaykeylaclvlamalgwanmlyytrgfqsmgmysvmiqkvilhdvlkflfvyilfllg
fgvalasliekcskdkkdcssygsfsdavlelfkltiglgdlniqqnstypilflfllit
yviltfvlllnmlialmgetvenvskeseriwrlqrartilefekmlpewlrsrfrmgel
ckvadedfrlclrinevkwtewkthvsflnedpgpirrtadlnkiqdssrsnskttlyaf
deldefpetsvlvprgsaaawshpqfek

    Sequence, based on observed residues (ATOM records):
    >6pvmB (B:)
kkkrlkkrifaavsegcveelrellqdlqdlcrrrrgldvpdflmhkltasdtgktclmk
allninpntkeivrillafaeendildrfinaeyteeayegqtalniaierrqgditavl
iaagadvnahakgvffnpkyqhegfyfgetplalaactnqpeivqllmeneqtditsqds
rgnnilhalvtvaedfktqndfvkrmydmillrsgnweletmrnndgltplqlaakmgka
eilkyilsreikekplrslsrkftdwaygpvssslydltnvdtttdnsvleiivyntnid
nrhemltleplhtllhtkwkkfakymfflsfcfyffynitltlvsyyrprededlphpla
lthkmswlqllgrmfvliwatcisvkegiaifllrpsdlqsilsdawfhfvffvqavlvi
lsvflylfaykeylaclvlamalgwanmlyytrgfqsmgmysvmiqkvilhdvlkflfvy
ilfllgfgvalasliekcskdkkdcssygsfsdavlelfkltiglgdlniqqnstypilf
lfllityviltfvlllnmlialmgetvenvskeseriwrlqrartilefekmlpewlrsr
frmgelckvadedfrlclrinevkwtewkthvsflnedpgpirr

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6pvmC (C:)
mnahskemaplmgkrttapggnpvvltekrpadltptkksahffleiegfepnptvtkts
ppifskpmdsnirqclsgncddmdspqspqddvtetpsnpnspsanlakeeqrqkkkrlk
krifaavsegcveelrellqdlqdlcrrrrgldvpdflmhkltasdtgktclmkallnin
pntkeivrillafaeendildrfinaeyteeayegqtalniaierrqgditavliaagad
vnahakgvffnpkyqhegfyfgetplalaactnqpeivqllmeneqtditsqdsrgnnil
halvtvaedfktqndfvkrmydmillrsgnweletmrnndgltplqlaakmgkaeilkyi
lsreikekplrslsrkftdwaygpvssslydltnvdtttdnsvleiivyntnidnrheml
tleplhtllhtkwkkfakymfflsfcfyffynitltlvsyyrprededlphplalthkms
wlqllgrmfvliwatcisvkegiaifllrpsdlqsilsdawfhfvffvqavlvilsvfly
lfaykeylaclvlamalgwanmlyytrgfqsmgmysvmiqkvilhdvlkflfvyilfllg
fgvalasliekcskdkkdcssygsfsdavlelfkltiglgdlniqqnstypilflfllit
yviltfvlllnmlialmgetvenvskeseriwrlqrartilefekmlpewlrsrfrmgel
ckvadedfrlclrinevkwtewkthvsflnedpgpirrtadlnkiqdssrsnskttlyaf
deldefpetsvlvprgsaaawshpqfek

    Sequence, based on observed residues (ATOM records):
    >6pvmC (C:)
kkkrlkkrifaavsegcveelrellqdlqdlcrrrrgldvpdflmhkltasdtgktclmk
allninpntkeivrillafaeendildrfinaeyteeayegqtalniaierrqgditavl
iaagadvnahakgvffnpkyqhegfyfgetplalaactnqpeivqllmeneqtditsqds
rgnnilhalvtvaedfktqndfvkrmydmillrsgnweletmrnndgltplqlaakmgka
eilkyilsreikekplrslsrkftdwaygpvssslydltnvdtttdnsvleiivyntnid
nrhemltleplhtllhtkwkkfakymfflsfcfyffynitltlvsyyrprededlphpla
lthkmswlqllgrmfvliwatcisvkegiaifllrpsdlqsilsdawfhfvffvqavlvi
lsvflylfaykeylaclvlamalgwanmlyytrgfqsmgmysvmiqkvilhdvlkflfvy
ilfllgfgvalasliekcskdkkdcssygsfsdavlelfkltiglgdlniqqnstypilf
lfllityviltfvlllnmlialmgetvenvskeseriwrlqrartilefekmlpewlrsr
frmgelckvadedfrlclrinevkwtewkthvsflnedpgpirr

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6pvmD (D:)
mnahskemaplmgkrttapggnpvvltekrpadltptkksahffleiegfepnptvtkts
ppifskpmdsnirqclsgncddmdspqspqddvtetpsnpnspsanlakeeqrqkkkrlk
krifaavsegcveelrellqdlqdlcrrrrgldvpdflmhkltasdtgktclmkallnin
pntkeivrillafaeendildrfinaeyteeayegqtalniaierrqgditavliaagad
vnahakgvffnpkyqhegfyfgetplalaactnqpeivqllmeneqtditsqdsrgnnil
halvtvaedfktqndfvkrmydmillrsgnweletmrnndgltplqlaakmgkaeilkyi
lsreikekplrslsrkftdwaygpvssslydltnvdtttdnsvleiivyntnidnrheml
tleplhtllhtkwkkfakymfflsfcfyffynitltlvsyyrprededlphplalthkms
wlqllgrmfvliwatcisvkegiaifllrpsdlqsilsdawfhfvffvqavlvilsvfly
lfaykeylaclvlamalgwanmlyytrgfqsmgmysvmiqkvilhdvlkflfvyilfllg
fgvalasliekcskdkkdcssygsfsdavlelfkltiglgdlniqqnstypilflfllit
yviltfvlllnmlialmgetvenvskeseriwrlqrartilefekmlpewlrsrfrmgel
ckvadedfrlclrinevkwtewkthvsflnedpgpirrtadlnkiqdssrsnskttlyaf
deldefpetsvlvprgsaaawshpqfek

    Sequence, based on observed residues (ATOM records):
    >6pvmD (D:)
kkkrlkkrifaavsegcveelrellqdlqdlcrrrrgldvpdflmhkltasdtgktclmk
allninpntkeivrillafaeendildrfinaeyteeayegqtalniaierrqgditavl
iaagadvnahakgvffnpkyqhegfyfgetplalaactnqpeivqllmeneqtditsqds
rgnnilhalvtvaedfktqndfvkrmydmillrsgnweletmrnndgltplqlaakmgka
eilkyilsreikekplrslsrkftdwaygpvssslydltnvdtttdnsvleiivyntnid
nrhemltleplhtllhtkwkkfakymfflsfcfyffynitltlvsyyrprededlphpla
lthkmswlqllgrmfvliwatcisvkegiaifllrpsdlqsilsdawfhfvffvqavlvi
lsvflylfaykeylaclvlamalgwanmlyytrgfqsmgmysvmiqkvilhdvlkflfvy
ilfllgfgvalasliekcskdkkdcssygsfsdavlelfkltiglgdlniqqnstypilf
lfllityviltfvlllnmlialmgetvenvskeseriwrlqrartilefekmlpewlrsr
frmgelckvadedfrlclrinevkwtewkthvsflnedpgpirr