PDB entry 6pul

View 6pul on RCSB PDB site
Description: Structure of human MAIT A-F7 TCR in complex with human MR1 3'D-5-OP-RU
Class: immune system
Keywords: MAIT, MR1, Metablite presentation, IMMUNE SYSTEM
Deposited on 2019-07-18, released 2020-02-19
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-04-01, with a file datestamp of 2020-03-27.
Experiment type: XRAY
Resolution: 1.84 Å
R-factor: N/A
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Major histocompatibility complex class I-related gene protein
    Species: Homo sapiens [TaxId:9606]
    Gene: MR1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q95460 (1-270)
      • initiating methionine (0)
      • conflict (261)
    Domains in SCOPe 2.08: d6pula1, d6pula2, d6pula3
  • Chain 'B':
    Compound: TRA@ protein
    Species: Homo sapiens [TaxId:9606]
    Gene: TRA@
    Database cross-references and differences (RAF-indexed):
    • PDB 6PUL
    Domains in SCOPe 2.08: d6pulb1, d6pulb2
  • Chain 'C':
    Compound: Major histocompatibility complex class I-related gene protein
    Species: Homo sapiens [TaxId:9606]
    Gene: MR1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q95460 (1-270)
      • initiating methionine (0)
      • conflict (261)
    Domains in SCOPe 2.08: d6pulc1, d6pulc2, d6pulc3
  • Chain 'D':
    Compound: TRA@ protein
    Species: Homo sapiens [TaxId:9606]
    Gene: TRA@
    Database cross-references and differences (RAF-indexed):
    • PDB 6PUL
    Domains in SCOPe 2.08: d6puld1, d6puld2
  • Chain 'E':
    Compound: Human TCR beta chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6PUL
    Domains in SCOPe 2.08: d6pule1, d6pule2
  • Chain 'F':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-99)
      • initiating methionine (0)
    Domains in SCOPe 2.08: d6pulf1, d6pulf2
  • Chain 'G':
    Compound: Human TCR beta chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6PUL
    Domains in SCOPe 2.08: d6pulg1, d6pulg2
  • Chain 'H':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-End)
      • initiating methionine (0)
    Domains in SCOPe 2.08: d6pulh1, d6pulh2
  • Heterogens: Q81, GOL, ACT, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6pulA (A:)
mrthslryfrlgvsdpihgvpefisvgyvdshpittydsvtrqkeprapwmaenlapdhw
erytqllrgwqqmfkvelkrlqrhynhsgshtyqrmigcelledgsttgflqyaydgqdf
lifnkdtlswlavdnvahtikqaweanqhellyqknwleeeciawlkrfleygkdtlqrt
epplvrvnrketfpgvtalfckahgfyppeiymtwmkngeeivqeidygdilpsgdgtyq
awasieldpqssnlyschvehsgvhmvlqvp

    Sequence, based on observed residues (ATOM records): (download) 
    >6pulA (A:)
mrthslryfrlgvsdpihgvpefisvgyvdshpittydsvtrqkeprapwmaenlapdhw
erytqllrgwqqmfkvelkrlqrhynhsgshtyqrmigcelledgsttgflqyaydgqdf
lifnkdtlswlavdnvahtikqaweanqhellyqknwleeeciawlkrfleygkdtlqrt
epplvrvnrktalfckahgfyppeiymtwmkngeeivqeidygdilpsgdgtyqawasie
ldpqssnlyschvehsgvhmvlqvp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6pulB (B:)
mgqnidqptemtategaivqinctyqtsgfnglfwyqqhageaptflsynvldgleekgr
fssflsrskgysylllkelqmkdsasylcavkdsnyqliwgagtkliikpdiqnpdpavy
qlrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnksd
facanafnnsiipedtffpspess

    Sequence, based on observed residues (ATOM records): (download) 
    >6pulB (B:)
gqnidqptemtategaivqinctyqtsgfnglfwyqqhageaptflsynvldgleekgrf
ssflsrskgysylllkelqmkdsasylcavkdsnyqliwgagtkliikpdiqnpdpavyq
lrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnksdf
acanafnnsiipedtffpsp

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6pulC (C:)
mrthslryfrlgvsdpihgvpefisvgyvdshpittydsvtrqkeprapwmaenlapdhw
erytqllrgwqqmfkvelkrlqrhynhsgshtyqrmigcelledgsttgflqyaydgqdf
lifnkdtlswlavdnvahtikqaweanqhellyqknwleeeciawlkrfleygkdtlqrt
epplvrvnrketfpgvtalfckahgfyppeiymtwmkngeeivqeidygdilpsgdgtyq
awasieldpqssnlyschvehsgvhmvlqvp

    Sequence, based on observed residues (ATOM records): (download) 
    >6pulC (C:)
mrthslryfrlgvsdpihgvpefisvgyvdshpittydsvtrqkeprapwmaenlapdhw
erytqllrgwqqmfkvelkrlqrhynhsgshtyqrmigcelledgsttgflqyaydgqdf
lifnkdtlswlavdnvahtikqaweanqhellyqknwleeeciawlkrfleygkdtlqrt
epplvrvnrketfpgvtalfckahgfyppeiymtwmkngeeivqeidygdilpsgdgtyq
awasielsnlyschvehsgvhmvlqvp

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6pulD (D:)
mgqnidqptemtategaivqinctyqtsgfnglfwyqqhageaptflsynvldgleekgr
fssflsrskgysylllkelqmkdsasylcavkdsnyqliwgagtkliikpdiqnpdpavy
qlrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnksd
facanafnnsiipedtffpspess

    Sequence, based on observed residues (ATOM records): (download) 
    >6pulD (D:)
gqnidqptemtategaivqinctyqtsgfnglfwyqqhageaptflsynvldgleekgrf
ssflsrskgysylllkelqmkdsasylcavkdsnyqliwgagtkliikpdiqnpdpavyq
lrdsksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnksdfacan
afnnsiipedtffps

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6pulE (E:)
mnagvtqtpkfqvlktgqsmtlqcaqdmnhnsmywyrqdpgmglrliyysasegttdkge
vpngynvsrlnkrefslrlesaapsqtsvyfcassvwtgegsgelffgegsrltvledlk
nvfppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplk
eqpalndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsae
awgrad

    Sequence, based on observed residues (ATOM records): (download) 
    >6pulE (E:)
agvtqtpkfqvlktgqsmtlqcaqdmnhnsmywyrqdpgmglrliyysasegttdkgevp
ngynvsrlnkrefslrlesaapsqtsvyfcassvwtgegsgelffgegsrltvledlknv
fppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplkeq
palndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaeaw
g

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6pulF (F:)
miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >6pulG (G:)
mnagvtqtpkfqvlktgqsmtlqcaqdmnhnsmywyrqdpgmglrliyysasegttdkge
vpngynvsrlnkrefslrlesaapsqtsvyfcassvwtgegsgelffgegsrltvledlk
nvfppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplk
eqpalndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsae
awgrad

    Sequence, based on observed residues (ATOM records): (download) 
    >6pulG (G:)
nagvtqtpkfqvlktgqsmtlqcaqdmnhnsmywyrqdpgmglrliyysasegttdkgev
pngynvsrlnkrefslrlesaapsqtsvyfcassvwtgegsgelffgegsrltvledlkn
vfppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplke
qpalndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaea
wgra

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >6pulH (H:)
miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

    Sequence, based on observed residues (ATOM records): (download) 
    >6pulH (H:)
miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdr