PDB entry 6puj

View 6puj on RCSB PDB site
Description: Structure of human MAIT A-F7 TCR in complex with human MR1-3`OH-Propyl-5-OP-U
Class: immune system
Keywords: MAIT, MR1, Metablite presentation, IMMUNE SYSTEM
Deposited on 2019-07-18, released 2020-02-19
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-04-01, with a file datestamp of 2020-03-27.
Experiment type: XRAY
Resolution: 1.92 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Major histocompatibility complex class I-related gene protein
    Species: Homo sapiens [TaxId:9606]
    Gene: MR1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q95460 (1-270)
      • initiating methionine (0)
      • conflict (261)
    Domains in SCOPe 2.08: d6puja1, d6puja2, d6puja3
  • Chain 'B':
    Compound: Human TCR alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: TRA@
    Database cross-references and differences (RAF-indexed):
    • PDB 6PUJ
    Domains in SCOPe 2.08: d6pujb1, d6pujb2
  • Chain 'C':
    Compound: Major histocompatibility complex class I-related gene protein
    Species: Homo sapiens [TaxId:9606]
    Gene: MR1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q95460 (1-270)
      • initiating methionine (0)
      • conflict (261)
    Domains in SCOPe 2.08: d6pujc1, d6pujc2, d6pujc3
  • Chain 'D':
    Compound: Human TCR alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: TRA@
    Database cross-references and differences (RAF-indexed):
    • PDB 6PUJ
    Domains in SCOPe 2.08: d6pujd1, d6pujd2
  • Chain 'E':
    Compound: Human TCR beta chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6PUJ
    Domains in SCOPe 2.08: d6puje1, d6puje2
  • Chain 'F':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed):
    • PDB 6PUJ (0-99)
    Domains in SCOPe 2.08: d6pujf_
  • Chain 'G':
    Compound: Human TCR beta chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6PUJ
    Domains in SCOPe 2.08: d6pujg1, d6pujg2
  • Chain 'H':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed):
    • PDB 6PUJ
    Domains in SCOPe 2.08: d6pujh_
  • Heterogens: Q7S, GOL, CL, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6pujA (A:)
mrthslryfrlgvsdpihgvpefisvgyvdshpittydsvtrqkeprapwmaenlapdhw
erytqllrgwqqmfkvelkrlqrhynhsgshtyqrmigcelledgsttgflqyaydgqdf
lifnkdtlswlavdnvahtikqaweanqhellyqknwleeeciawlkrfleygkdtlqrt
epplvrvnrketfpgvtalfckahgfyppeiymtwmkngeeivqeidygdilpsgdgtyq
awasieldpqssnlyschvehsgvhmvlqvp

    Sequence, based on observed residues (ATOM records): (download) 
    >6pujA (A:)
mrthslryfrlgvsdpihgvpefisvgyvdshpittydsvtrqkeprapwmaenlapdhw
erytqllrgwqqmfkvelkrlqrhynhsgshtyqrmigcelledgsttgflqyaydgqdf
lifnkdtlswlavdnvahtikqaweanqhellyqknwleeeciawlkrfleygkdtlqrt
epplvrvnrktalfckahgfyppeiymtwmkngeeivqeidygdilpsgdgtyqawasie
ldpqssnlyschvehsgvhmvlqvp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6pujB (B:)
mgqnidqptemtategaivqinctyqtsgfnglfwyqqhageaptflsynvldgleekgr
fssflsrskgysylllkelqmkdsasylcavkdsnyqliwgagtkliikpdiqnpdpavy
qlrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnksd
facanafnnsiipedtffpspess

    Sequence, based on observed residues (ATOM records): (download) 
    >6pujB (B:)
gqnidqptemtategaivqinctyqtsgfnglfwyqqhageaptflsynvldgleekgrf
ssflsrskgysylllkelqmkdsasylcavkdsnyqliwgagtkliikpdiqnpdpavyq
lrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnksdf
acanafnnsiipedtffpsp

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6pujC (C:)
mrthslryfrlgvsdpihgvpefisvgyvdshpittydsvtrqkeprapwmaenlapdhw
erytqllrgwqqmfkvelkrlqrhynhsgshtyqrmigcelledgsttgflqyaydgqdf
lifnkdtlswlavdnvahtikqaweanqhellyqknwleeeciawlkrfleygkdtlqrt
epplvrvnrketfpgvtalfckahgfyppeiymtwmkngeeivqeidygdilpsgdgtyq
awasieldpqssnlyschvehsgvhmvlqvp

    Sequence, based on observed residues (ATOM records): (download) 
    >6pujC (C:)
mrthslryfrlgvsdpihgvpefisvgyvdshpittydsvtrqkeprapwmaenlapdhw
erytqllrgwqqmfkvelkrlqrhynhsgshtyqrmigcelledgsttgflqyaydgqdf
lifnkdtlswlavdnvahtikqaweanqhellyqknwleeeciawlkrfleygkdtlqrt
epplvrvnrketfpgvtalfckahgfyppeiymtwmkngeeivqeidygdilpsgdgtyq
awasieldssnlyschvehsgvhmvlqvp

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6pujD (D:)
mgqnidqptemtategaivqinctyqtsgfnglfwyqqhageaptflsynvldgleekgr
fssflsrskgysylllkelqmkdsasylcavkdsnyqliwgagtkliikpdiqnpdpavy
qlrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnksd
facanafnnsiipedtffpspess

    Sequence, based on observed residues (ATOM records): (download) 
    >6pujD (D:)
gqnidqptemtategaivqinctyqtsgfnglfwyqqhageaptflsynvldgleekgrf
ssflsrskgysylllkelqmkdsasylcavkdsnyqliwgagtkliikpdiqnpdpavyq
lrdsksksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnksdfac
anafnnsiipedtffp

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6pujE (E:)
mnagvtqtpkfqvlktgqsmtlqcaqdmnhnsmywyrqdpgmglrliyysasegttdkge
vpngynvsrlnkrefslrlesaapsqtsvyfcassvwtgegsgelffgegsrltvledlk
nvfppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplk
eqpalndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsae
awgrad

    Sequence, based on observed residues (ATOM records): (download) 
    >6pujE (E:)
gvtqtpkfqvlktgqsmtlqcaqdmnhnsmywyrqdpgmglrliyysasegttdkgevpn
gynvsrlnkrefslrlesaapsqtsvyfcassvwtgegsgelffgegsrltvledlknvf
ppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplkeqp
alndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaeawg
ra

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6pujF (F:)
miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >6pujG (G:)
mnagvtqtpkfqvlktgqsmtlqcaqdmnhnsmywyrqdpgmglrliyysasegttdkge
vpngynvsrlnkrefslrlesaapsqtsvyfcassvwtgegsgelffgegsrltvledlk
nvfppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplk
eqpalndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsae
awgrad

    Sequence, based on observed residues (ATOM records): (download) 
    >6pujG (G:)
nagvtqtpkfqvlktgqsmtlqcaqdmnhnsmywyrqdpgmglrliyysasegttdkgev
pngynvsrlnkrefslrlesaapsqtsvyfcassvwtgegsgelffgegsrltvledlkn
vfppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplke
qpalndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaea
wgra

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >6pujH (H:)
miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

    Sequence, based on observed residues (ATOM records): (download) 
    >6pujH (H:)
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwdr