PDB entry 6ptu

View 6ptu on RCSB PDB site
Description: Crystal Structure of Class D Beta-lactamase OXA-48 with Imipenem
Class: hydrolase
Keywords: Carbapenemase, Carbapenem, substrate, Hydrolyzed product, HYDROLASE
Deposited on 2019-07-16, released 2020-01-22
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-08-05, with a file datestamp of 2020-07-31.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Class D Carbapenemase OXA-48
    Species: Klebsiella pneumoniae [TaxId:573]
    Gene: blaOXA
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A482LRD5 (22-262)
      • expression tag (20-21)
    Domains in SCOPe 2.08: d6ptua1, d6ptua2
  • Chain 'B':
    Compound: Class D Carbapenemase OXA-48
    Species: Klebsiella pneumoniae [TaxId:573]
    Gene: blaOXA
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A482LRD5 (22-262)
      • expression tag (19-21)
    Domains in SCOPe 2.08: d6ptub1, d6ptub2
  • Chain 'C':
    Compound: Class D Carbapenemase OXA-48
    Species: Klebsiella pneumoniae [TaxId:573]
    Gene: blaOXA
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A482LRD5 (22-262)
      • expression tag (19-21)
    Domains in SCOPe 2.08: d6ptuc1, d6ptuc2
  • Chain 'D':
    Compound: Class D Carbapenemase OXA-48
    Species: Klebsiella pneumoniae [TaxId:573]
    Gene: blaOXA
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A482LRD5 (22-262)
      • expression tag (19-21)
    Domains in SCOPe 2.08: d6ptud1, d6ptud2
  • Heterogens: ID1, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6ptuA (A:)
mkhhhhhhmhhhhhhenlyfqgwqenkswnahftehksqgvvvlwnenkqqgftnnlkra
nqaflpastfkipnslialdlgvvkdehqvfkwdgqtrdiatwnrdhnlitamkysvvpv
yqefarqigearmskmlhafdygnedisgnvdsfwldggirisateqisflrklyhnklh
vsersqrivkqamlteangdyiiraktgystriepkigwwvgwvelddnvwffamnmdmp
tsdglglrqaitkevlkqekiip

    Sequence, based on observed residues (ATOM records): (download) 
    >6ptuA (A:)
qgwqenkswnahftehksqgvvvlwnenkqqgftnnlkranqaflpastfkipnsliald
lgvvkdehqvfkwdgqtrdiatwnrdhnlitamkysvvpvyqefarqigearmskmlhaf
dygnedisgnvdsfwldggirisateqisflrklyhnklhvsersqrivkqamlteangd
yiiraktgystriepkigwwvgwvelddnvwffamnmdmptsdglglrqaitkevlkqek
iip

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6ptuB (B:)
mkhhhhhhmhhhhhhenlyfqgwqenkswnahftehksqgvvvlwnenkqqgftnnlkra
nqaflpastfkipnslialdlgvvkdehqvfkwdgqtrdiatwnrdhnlitamkysvvpv
yqefarqigearmskmlhafdygnedisgnvdsfwldggirisateqisflrklyhnklh
vsersqrivkqamlteangdyiiraktgystriepkigwwvgwvelddnvwffamnmdmp
tsdglglrqaitkevlkqekiip

    Sequence, based on observed residues (ATOM records): (download) 
    >6ptuB (B:)
fqgwqenkswnahftehksqgvvvlwnenkqqgftnnlkranqaflpastfkipnslial
dlgvvkdehqvfkwdgqtrdiatwnrdhnlitamkysvvpvyqefarqigearmskmlha
fdygnedisgnvdsfwldggirisateqisflrklyhnklhvsersqrivkqamlteang
dyiiraktgystriepkigwwvgwvelddnvwffamnmdmptsdglglrqaitkevlkqe
kiip

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6ptuC (C:)
mkhhhhhhmhhhhhhenlyfqgwqenkswnahftehksqgvvvlwnenkqqgftnnlkra
nqaflpastfkipnslialdlgvvkdehqvfkwdgqtrdiatwnrdhnlitamkysvvpv
yqefarqigearmskmlhafdygnedisgnvdsfwldggirisateqisflrklyhnklh
vsersqrivkqamlteangdyiiraktgystriepkigwwvgwvelddnvwffamnmdmp
tsdglglrqaitkevlkqekiip

    Sequence, based on observed residues (ATOM records): (download) 
    >6ptuC (C:)
fqgwqenkswnahftehksqgvvvlwnenkqqgftnnlkranqaflpastfkipnslial
dlgvvkdehqvfkwdgqtrdiatwnrdhnlitamkysvvpvyqefarqigearmskmlha
fdygnedisgnvdsfwldggirisateqisflrklyhnklhvsersqrivkqamlteang
dyiiraktgystriepkigwwvgwvelddnvwffamnmdmptsdglglrqaitkevlkqe
kiip

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6ptuD (D:)
mkhhhhhhmhhhhhhenlyfqgwqenkswnahftehksqgvvvlwnenkqqgftnnlkra
nqaflpastfkipnslialdlgvvkdehqvfkwdgqtrdiatwnrdhnlitamkysvvpv
yqefarqigearmskmlhafdygnedisgnvdsfwldggirisateqisflrklyhnklh
vsersqrivkqamlteangdyiiraktgystriepkigwwvgwvelddnvwffamnmdmp
tsdglglrqaitkevlkqekiip

    Sequence, based on observed residues (ATOM records): (download) 
    >6ptuD (D:)
fqgwqenkswnahftehksqgvvvlwnenkqqgftnnlkranqaflpastfkipnslial
dlgvvkdehqvfkwdgqtrdiatwnrdhnlitamkysvvpvyqefarqigearmskmlha
fdygnedisgnvdsfwldggirisateqisflrklyhnklhvsersqrivkqamlteang
dyiiraktgystriepkigwwvgwvelddnvwffamnmdmptsdglglrqaitkevlkqe
kiip