PDB entry 6pr1

View 6pr1 on RCSB PDB site
Description: R260A/S128A S. typhimurium siroheme synthase
Class: transferase
Keywords: precorrin-2, tetrapyrrole biosynthesis, CysG, TRANSFERASE
Deposited on 2019-07-10, released 2020-02-26
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-02-26, with a file datestamp of 2020-02-21.
Experiment type: XRAY
Resolution: 1.82 Å
R-factor: N/A
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Siroheme synthase
    Species: Salmonella typhimurium [TaxId:90371]
    Gene: cysG, cobA, AAP89_23165, ABO94_22995, AF480_23265, AF488_22710, AF489_21700, AIC76_23675, AXR84_23260, AXU58_22185, C2253_19735, CD48_22680, CE87_23070, CET98_25025, CVR97_13625, D7F20_23535, D7H43_21790, DJ388_17225, E2F01_22980, FCJ89_03505, FGA22_01875, FGA24_01980, FGA25_01865, FGA26_01870, GW08_22845, JO10_22525, LZ63_24065, NCTC13348_03825, NG18_22490, NU83_22495, QA89_22165, QB40_24005, QD15_23475, RJ78_23420, SE14_03689, Y934_21155, YG50_22125, YI33_23225, YR17_23015, ZC54_23835
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A0F7JCI1 (0-456)
      • engineered mutation (127)
      • engineered mutation (259)
    Domains in SCOPe 2.08: d6pr1a1, d6pr1a2, d6pr1a3
  • Chain 'B':
    Compound: Siroheme synthase
    Species: Salmonella typhimurium [TaxId:90371]
    Gene: cysG, cobA, AAP89_23165, ABO94_22995, AF480_23265, AF488_22710, AF489_21700, AIC76_23675, AXR84_23260, AXU58_22185, C2253_19735, CD48_22680, CE87_23070, CET98_25025, CVR97_13625, D7F20_23535, D7H43_21790, DJ388_17225, E2F01_22980, FCJ89_03505, FGA22_01875, FGA24_01980, FGA25_01865, FGA26_01870, GW08_22845, JO10_22525, LZ63_24065, NCTC13348_03825, NG18_22490, NU83_22495, QA89_22165, QB40_24005, QD15_23475, RJ78_23420, SE14_03689, Y934_21155, YG50_22125, YI33_23225, YR17_23015, ZC54_23835
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A0F7JCI1 (0-456)
      • engineered mutation (127)
      • engineered mutation (259)
    Domains in SCOPe 2.08: d6pr1b1, d6pr1b2, d6pr1b3
  • Heterogens: CL, SAH, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6pr1A (A:)
mdhlpifcqlrdrdclivgggdvaerkarllleagarltvnaltfipqftvwanegmltl
vegpfdetlldscwlaiaatdddtvnqrvsdaaesrrifcnvvdapkaasfimpsiidrs
plmvavsaggtspvlarllreklesllpqhlgqvaryagqlrarvkkqfatmgerrrfwe
kffvndrlaqslanadekavnatterlfsepldhrgevvlvgagpgdaglltlkglqqiq
qadivvydrlvsddimnlvardadrvfvgkragyhcvpqeeinqillreaqkgkrvvrlk
ggdpfifgrggeeletlchagipfsvvpgitaasgcsaysgiplthrdyaqsvrlvtghl
ktggeldwenlaaekqtlvfymglnqaatiqekliafgmqadmpvalvengtsvkqrvvh
gvltqlgelaqqvespaliivgrvvalrdklnwfsnh

    Sequence, based on observed residues (ATOM records): (download) 
    >6pr1A (A:)
mdhlpifcqlrdrdclivgggdvaerkarllleagarltvnaltfipqftvwanegmltl
vegpfdetlldscwlaiaatdddtvnqrvsdaaesrrifcnvvdapkaasfimpsiidrs
plmvavsaggtspvlarllreklesllpqhlgqvaryagqlrarvkkqfatmgerrrfwe
kffvndrlaqslanadekavnatterlfsepldhrgevvlvgagpgdaglltlkglqqiq
qadivvydrlvsddimnlvardadrvfvgvpqeeinqillreaqkgkrvvrlkggdpfif
grggeeletlchagipfsvvpgitaasgcsaysgiplthrdyaqsvrlvtghlktggeld
wenlaaekqtlvfymglnqaatiqekliafgmqadmpvalvengtsvkqrvvhgvltqlg
elaqqvespaliivgrvvalrdklnwfsnh

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6pr1B (B:)
mdhlpifcqlrdrdclivgggdvaerkarllleagarltvnaltfipqftvwanegmltl
vegpfdetlldscwlaiaatdddtvnqrvsdaaesrrifcnvvdapkaasfimpsiidrs
plmvavsaggtspvlarllreklesllpqhlgqvaryagqlrarvkkqfatmgerrrfwe
kffvndrlaqslanadekavnatterlfsepldhrgevvlvgagpgdaglltlkglqqiq
qadivvydrlvsddimnlvardadrvfvgkragyhcvpqeeinqillreaqkgkrvvrlk
ggdpfifgrggeeletlchagipfsvvpgitaasgcsaysgiplthrdyaqsvrlvtghl
ktggeldwenlaaekqtlvfymglnqaatiqekliafgmqadmpvalvengtsvkqrvvh
gvltqlgelaqqvespaliivgrvvalrdklnwfsnh

    Sequence, based on observed residues (ATOM records): (download) 
    >6pr1B (B:)
mdhlpifcqlrdrdclivgggdvaerkarllleagarltvnaltfipqftvwanegmltl
vegpfdetlldscwlaiaatdddtvnqrvsdaaesrrifcnvvdapkaasfimpsiidrs
plmvavsaggtspvlarllreklesllpqhlgqvaryagqlrarvkkqfatmgerrrfwe
kffvndrlaqslanadekavnatterlfsepldhrgevvlvgagpgdaglltlkglqqiq
qadivvydrlvsddimnlvardadrvfvgkhcvpqeeinqillreaqkgkrvvrlkggdp
fifgrggeeletlchagipfsvvpgitaasgcsaysgiplthrdyaqsvrlvtgggeldw
enlaaekqtlvfymglnqaatiqekliafgmqadmpvalvengtsvkqrvvhgvltqlge
laqqvespaliivgrvvalrdklnwfsnh