PDB entry 6pqz

View 6pqz on RCSB PDB site
Description: P133G/S128A S. typhimurium siroheme synthase
Class: biosynthetic protein
Keywords: precorrin-2, tetrapyrrole biosynthesis, CysG, BIOSYNTHETIC PROTEIN
Deposited on 2019-07-10, released 2020-02-26
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-02-26, with a file datestamp of 2020-02-21.
Experiment type: XRAY
Resolution: 2.23 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Siroheme synthase
    Species: Salmonella typhimurium [TaxId:90371]
    Gene: cysG, cobA, AAP89_23165, ABO94_22995, AF480_23265, AF488_22710, AF489_21700, AIC76_23675, AXR84_23260, AXU58_22185, C2253_19735, CD48_22680, CE87_23070, CET98_25025, CVR97_13625, D7F20_23535, D7H43_21790, DJ388_17225, E2F01_22980, FCJ89_03505, FGA22_01875, FGA24_01980, FGA25_01865, FGA26_01870, GW08_22845, JO10_22525, LZ63_24065, NCTC13348_03825, NG18_22490, NU83_22495, QA89_22165, QB40_24005, QD15_23475, RJ78_23420, SE14_03689, Y934_21155, YG50_22125, YI33_23225, YR17_23015, ZC54_23835
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A0F7JCI1 (0-456)
      • engineered mutation (127)
      • engineered mutation (132)
    Domains in SCOPe 2.08: d6pqza1, d6pqza2, d6pqza3
  • Chain 'B':
    Compound: Siroheme synthase
    Species: Salmonella typhimurium [TaxId:90371]
    Gene: cysG, cobA, AAP89_23165, ABO94_22995, AF480_23265, AF488_22710, AF489_21700, AIC76_23675, AXR84_23260, AXU58_22185, C2253_19735, CD48_22680, CE87_23070, CET98_25025, CVR97_13625, D7F20_23535, D7H43_21790, DJ388_17225, E2F01_22980, FCJ89_03505, FGA22_01875, FGA24_01980, FGA25_01865, FGA26_01870, GW08_22845, JO10_22525, LZ63_24065, NCTC13348_03825, NG18_22490, NU83_22495, QA89_22165, QB40_24005, QD15_23475, RJ78_23420, SE14_03689, Y934_21155, YG50_22125, YI33_23225, YR17_23015, ZC54_23835
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A0F7JCI1 (0-End)
      • engineered mutation (127)
      • engineered mutation (132)
    Domains in SCOPe 2.08: d6pqzb1, d6pqzb2, d6pqzb3
  • Heterogens: SAH, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6pqzA (A:)
mdhlpifcqlrdrdclivgggdvaerkarllleagarltvnaltfipqftvwanegmltl
vegpfdetlldscwlaiaatdddtvnqrvsdaaesrrifcnvvdapkaasfimpsiidrs
plmvavsaggtsgvlarllreklesllpqhlgqvaryagqlrarvkkqfatmgerrrfwe
kffvndrlaqslanadekavnatterlfsepldhrgevvlvgagpgdaglltlkglqqiq
qadivvydrlvsddimnlvrrdadrvfvgkragyhcvpqeeinqillreaqkgkrvvrlk
ggdpfifgrggeeletlchagipfsvvpgitaasgcsaysgiplthrdyaqsvrlvtghl
ktggeldwenlaaekqtlvfymglnqaatiqekliafgmqadmpvalvengtsvkqrvvh
gvltqlgelaqqvespaliivgrvvalrdklnwfsnh

    Sequence, based on observed residues (ATOM records): (download) 
    >6pqzA (A:)
mdhlpifcqlrdrdclivgggdvaerkarllleagarltvnaltfipqftvwanegmltl
vegpfdetlldscwlaiaatdddtvnqrvsdaaesrrifcnvvdapkaasfimpsiidrs
plmvavsaggtsgvlarllreklesllpqhlgqvaryagqlrarvkkqfatmgerrrfwe
kffvndrlaqslanadekavnatterlfsepldhrgevvlvgagpgdaglltlkglqqiq
qadivvydrlvsddimnlvrrdadrvfvgkvpqeeinqillreaqkgkrvvrlkggdpfi
fgrggeeletlchagipfsvvpgitaasgcsaysgiplthrdyaqsvrlvtghlktggel
dwenlaaekqtlvfymglnqaatiqekliafgmqadmpvalvengtsvkqrvvhgvltql
gelaqqvespaliivgrvvalrdklnwfsnh

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6pqzB (B:)
mdhlpifcqlrdrdclivgggdvaerkarllleagarltvnaltfipqftvwanegmltl
vegpfdetlldscwlaiaatdddtvnqrvsdaaesrrifcnvvdapkaasfimpsiidrs
plmvavsaggtsgvlarllreklesllpqhlgqvaryagqlrarvkkqfatmgerrrfwe
kffvndrlaqslanadekavnatterlfsepldhrgevvlvgagpgdaglltlkglqqiq
qadivvydrlvsddimnlvrrdadrvfvgkragyhcvpqeeinqillreaqkgkrvvrlk
ggdpfifgrggeeletlchagipfsvvpgitaasgcsaysgiplthrdyaqsvrlvtghl
ktggeldwenlaaekqtlvfymglnqaatiqekliafgmqadmpvalvengtsvkqrvvh
gvltqlgelaqqvespaliivgrvvalrdklnwfsnh

    Sequence, based on observed residues (ATOM records): (download) 
    >6pqzB (B:)
mdhlpifcqlrdrdclivgggdvaerkarllleagarltvnaltfipqftvwanegmltl
vegpfdetlldscwlaiaatdddtvnqrvsdaaesrrifcnvvdapkaasfimpsiidrs
plmvavsaggtsgvlarllreklesllpqhlgqvaryagqlrarvkkqfatmgerrrfwe
kffvndrlaqslanadekavnatterlfsepldhrgevvlvgagpgdaglltlkglqqiq
qadivvydrlvsddimnlvrrdadrvfvgkvpqeeinqillreaqkgkrvvrlkggdpfi
fgrggeeletlchagipfsvvpgitaasgcsaysgiplthrdyaqsvrlvtgggeldwen
laaekqtlvfymglnqaatiqekliafgmqadmpvalvengtsvkqrvvhgvltqlgela
qqvespaliivgrvvalrdklnwfs