PDB entry 6ppg

View 6ppg on RCSB PDB site
Description: Crystal structure of IL17FF bound to Fab fragments of MCAF5352A
Class: cytokine
Keywords: IL-17, cytokine, complex
Deposited on 2019-07-06, released 2019-12-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.75 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Fab MCAF5352A light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6PPG (0-End)
    Domains in SCOPe 2.08: d6ppga1, d6ppga2
  • Chain 'B':
    Compound: Fab MCAF5352A heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6PPG (0-End)
    Domains in SCOPe 2.08: d6ppgb_
  • Chain 'F':
    Compound: Interleukin-17F
    Species: Homo sapiens [TaxId:9606]
    Gene: IL17F
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6ppgf_
  • Chain 'G':
    Compound: Interleukin-17F
    Species: Homo sapiens [TaxId:9606]
    Gene: IL17F
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6ppgg_
  • Chain 'H':
    Compound: Fab MCAF5352A heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6PPG (0-225)
    Domains in SCOPe 2.08: d6ppgh_
  • Chain 'L':
    Compound: Fab MCAF5352A light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6PPG (0-215)
    Domains in SCOPe 2.08: d6ppgl1, d6ppgl2
  • Heterogens: NAG, CD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6ppgA (A:)
eivltqspatlslspgeratlscrasqsvrsylawyqqkpgqaprlliydasnratgipa
rfsgsgsgtdftltisslepedfavyycqqrsnwppatfgggtkveikrtvaapsvfifp
psdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstl
tlskadyekhkvyacevthqglsspvtksfnrgegc

    Sequence, based on observed residues (ATOM records): (download) 
    >6ppgA (A:)
eivltqspatlslspgeratlscrasqsvrsylawyqqkpgqaprlliydasnratgipa
rfsgsgsgtdftltisslepedfavyycqqrsnwppatfgggtkveikrtvaapsvfifp
psdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstl
tlskadyekhkvyacevthqglsspvtksfnr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6ppgB (B:)
evqlvesggglvqpgrslrlscaasgftfddyamhwvrqapgkglewvsginwssggigy
adsvkgrftisrdnaknslylqmnslraedtalyycardiggfgefywnfglwgrgtlvt
vssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavl
qssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepksc

    Sequence, based on observed residues (ATOM records): (download) 
    >6ppgB (B:)
evqlvesggglvqpgrslrlscaasgftfddyamhwvrqapgkglewvsginwssggigy
adsvkgrftisrdnaknslylqmnslraedtalyycardiggfgefywnfglwgrgtlvt
vssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavl
qssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvep

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >6ppgF (F:)
rkipkvghtffqkpescppvpggsmkldigiinenqrvsmsrniesrstspwnytvtwdp
nrypsevvqaqcrnlgcinaqgkedismnsvpiqqetlvvrrkhqgcsvsfqlekvlvtv
gctcvtpvihhvq

    Sequence, based on observed residues (ATOM records): (download) 
    >6ppgF (F:)
tffsmkldigiinenqrvsmsrniesrstspwnytvtwdpnrypsevvqaqcrnlgcina
qgkedismnsvpiqqetlvvrrkhqgcsvsfqlekvlvtvgctcvtpvi

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >6ppgG (G:)
rkipkvghtffqkpescppvpggsmkldigiinenqrvsmsrniesrstspwnytvtwdp
nrypsevvqaqcrnlgcinaqgkedismnsvpiqqetlvvrrkhqgcsvsfqlekvlvtv
gctcvtpvihhvq

    Sequence, based on observed residues (ATOM records): (download) 
    >6ppgG (G:)
tffqkpescpsmkldigiinenqrvsmsrniesrstspwnytvtwdpnrypsevvqaqcr
nlgcinaqgkedismnsvpiqqetlvvrrkhqgcsvsfqlekvlvtvgctcvtpvih

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6ppgH (H:)
evqlvesggglvqpgrslrlscaasgftfddyamhwvrqapgkglewvsginwssggigy
adsvkgrftisrdnaknslylqmnslraedtalyycardiggfgefywnfglwgrgtlvt
vssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavl
qssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepksc

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6ppgL (L:)
eivltqspatlslspgeratlscrasqsvrsylawyqqkpgqaprlliydasnratgipa
rfsgsgsgtdftltisslepedfavyycqqrsnwppatfgggtkveikrtvaapsvfifp
psdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstl
tlskadyekhkvyacevthqglsspvtksfnrgegc