PDB entry 6plk

View 6plk on RCSB PDB site
Description: Crystal structure of ZIKV-116 Fab in complex with ZIKV envelope DIII
Class: antiviral protein
Keywords: Human antibody, ZIKV-DIII, ANTIVIRAL PROTEIN, Structural Genomics, Center for Structural Genomics of Infectious Diseases, CSGID
Deposited on 2019-07-01, released 2019-11-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-12-18, with a file datestamp of 2019-12-13.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'E':
    Compound: Env
    Species: Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013 [TaxId:2043570]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6plke_
  • Chain 'F':
    Compound: Env
    Species: Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013 [TaxId:2043570]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6plkf_
  • Chain 'H':
    Compound: ZIKV-116 heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6PLK (0-224)
    Domains in SCOPe 2.08: d6plkh_
  • Chain 'I':
    Compound: ZIKV-116 heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6PLK (0-224)
    Domains in SCOPe 2.08: d6plki_
  • Chain 'L':
    Compound: ZIKV-116 light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6PLK (0-213)
    Domains in SCOPe 2.08: d6plkl1, d6plkl2
  • Chain 'M':
    Compound: ZIKV-116 light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6PLK (0-213)
    Domains in SCOPe 2.08: d6plkm1, d6plkm2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6plkE (E:)
mrlkgvsyslctaaftftkipaetlhgtvtvevqyagtdgpckvpaqmavdmqtltpvgr
litanpvitestenskmmleldppfgdsyivigvgekkithhwhrsgsti

    Sequence, based on observed residues (ATOM records): (download) 
    >6plkE (E:)
vsyslctaaftftkipaetlhgtvtvevqyagtdgpckvpaqmavdmqtltpvgrlitan
pvitestenskmmleldppfgdsyivigvgekkithhwhrsgs

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >6plkF (F:)
mrlkgvsyslctaaftftkipaetlhgtvtvevqyagtdgpckvpaqmavdmqtltpvgr
litanpvitestenskmmleldppfgdsyivigvgekkithhwhrsgsti

    Sequence, based on observed residues (ATOM records): (download) 
    >6plkF (F:)
vsyslctaaftftkipaetlhgtvtvevqyagtdgpckvpaqmavdmqtltpvgrlitan
pvitestenskmmleldppfgdsyivigvgekkithhwhrsgs

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6plkH (H:)
evqlvqsgrglvrpggslrlscaasgftfsnyamswvrqgpgmglewvstitadsdskyy
vdsvkgrftisrdnskdtlflhmtslraedtavyycakdrlsrgvgelydswgqgtlvtv
ssasfkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlq
ssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepksc

  • Chain 'I':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6plkI (I:)
evqlvqsgrglvrpggslrlscaasgftfsnyamswvrqgpgmglewvstitadsdskyy
vdsvkgrftisrdnskdtlflhmtslraedtavyycakdrlsrgvgelydswgqgtlvtv
ssasfkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlq
ssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepksc

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6plkL (L:)
divmtqspstlsasvgdrvtitcrasqsidvwlawyqqkpgkapkllmyktstlqtgvps
rfsgsgsgteftltisslqtddfatyycqkydsypwtfgpgtkveikrtaaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrgec

  • Chain 'M':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6plkM (M:)
divmtqspstlsasvgdrvtitcrasqsidvwlawyqqkpgkapkllmyktstlqtgvps
rfsgsgsgteftltisslqtddfatyycqkydsypwtfgpgtkveikrtaaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrgec