PDB entry 6plc

View 6plc on RCSB PDB site
Description: structure of human dna polymerase eta complexed with 8oa in the template base paired with incoming non-hydrolyzable gtp
Deposited on 2019-06-30, released 2020-04-22
The last revision was dated 2020-05-27, with a file datestamp of 2020-05-22.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA Polymerase ETA
    Species: Homo sapiens [TaxId:9606]
    Gene: POLH, RAD30, RAD30A, XPV
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9Y253 (3-434)
      • expression tag (0-2)
  • Chain 'P':
    Compound: DNA (5'-d(*ap*gp*cp*gp*tp*cp*ap*t)-3')
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
  • Chain 'T':
    Compound: DNA (5'-d(*cp*ap*tp*(a38)p*ap*tp*gp*ap*cp*gp*cp*t)-3')
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
  • Heterogens: A38, XG4, MG, GOL, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6plcA (A:)
gphmatgqdrvvalvdmdcffvqveqrqnphlrnkpcavvqykswkgggiiavsyearaf
gvtrsmwaddakklcpdlllaqvresrgkanltkyreasvevmeimsrfavierasidea
yvdltsavqerlqklqgqpisadllpstyieglpqgpttaeetvqkegmrkqglfqwlds
lqidnltspdlqltvgaviveemraaieretgfqcsagishnkvlaklacglnkpnrqtl
vshgsvpqlfsqmpirkirslggklgasvieilgieymgeltqftesqlqshfgekngsw
lyamcrgiehdpvkprqlpktigcsknfpgktalatreqvqwwllqlaqeleerltkdrn
dndrvatqlvvsirvqgdkrlsslrrccaltrydahkmshdaftvikncntsgiqtewsp
pltmlflcatkfsas

    Sequence, based on observed residues (ATOM records):
    >6plcA (A:)
gphmatgqdrvvalvdmdcffvqveqrqnphlrnkpcavvqykswkgggiiavsyearaf
gvtrsmwaddakklcpdlllaqvresrgkanltkyreasvevmeimsrfavierasidea
yvdltsavqerlqklqgqpisadllpstyieglpqgptvqkegmrkqglfqwldslqidn
ltspdlqltvgaviveemraaieretgfqcsagishnkvlaklacglnkpnrqtlvshgs
vpqlfsqmpirkirslggklgasvieilgieymgeltqftesqlqshfgekngswlyamc
rgiehdpvkprqlpktigcsknfpgktalatreqvqwwllqlaqeleerltkdrndndrv
atqlvvsirvqgdkrlsslrrccaltrydahkmshdaftvikncntsgiqtewsppltml
flcatkfsas

  • Chain 'P':
    No sequence available.

  • Chain 'T':
    No sequence available.