PDB entry 6pjc

View 6pjc on RCSB PDB site
Description: HIV-1 Protease NL4-3 WT in Complex with LR4-41
Class: hydrolase/hydrolase inhibitor
Keywords: HIV, NL4-3 PROTEASE, DRUG RESISTANCE, PROTEASE INHIBITOR, HYDROLASE INHIBITOR COMPLEX, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2019-06-28, released 2020-07-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-08-26, with a file datestamp of 2020-08-21.
Experiment type: XRAY
Resolution: 1.97 Å
R-factor: N/A
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Protease NL4-3
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8ULI9 (0-98)
      • engineered mutation (6)
    Domains in SCOPe 2.08: d6pjca_
  • Chain 'B':
    Compound: Protease NL4-3
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8ULI9 (0-98)
      • engineered mutation (6)
    Domains in SCOPe 2.08: d6pjcb_
  • Chain 'C':
    Compound: Protease NL4-3
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8ULI9 (0-98)
      • engineered mutation (6)
    Domains in SCOPe 2.08: d6pjcc_
  • Chain 'D':
    Compound: Protease NL4-3
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8ULI9 (0-98)
      • engineered mutation (6)
    Domains in SCOPe 2.08: d6pjcd_
  • Heterogens: OR1, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6pjcA (A:)
pqitlwkrplvtikiggqlkealldtgaddtvleemnlpgrwkpkmiggiggfikvrqyd
qilieicghkaigtvlvgptpvniigrnlltqigctlnf

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6pjcB (B:)
pqitlwkrplvtikiggqlkealldtgaddtvleemnlpgrwkpkmiggiggfikvrqyd
qilieicghkaigtvlvgptpvniigrnlltqigctlnf

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6pjcC (C:)
pqitlwkrplvtikiggqlkealldtgaddtvleemnlpgrwkpkmiggiggfikvrqyd
qilieicghkaigtvlvgptpvniigrnlltqigctlnf

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6pjcD (D:)
pqitlwkrplvtikiggqlkealldtgaddtvleemnlpgrwkpkmiggiggfikvrqyd
qilieicghkaigtvlvgptpvniigrnlltqigctlnf