PDB entry 6pia

View 6pia on RCSB PDB site
Description: Crystal structure of Marinobacter subterrani acetylpolyamine amidohydrolase (msAPAH) complexed with 6-[(3-aminopropyl)amino]-N-hydroxyhexanamide
Class: hydrolase/inhibitor
Keywords: acetylpolyamine amidohydrolase, polyamine deacetylase, hydrolase, hydrolase inhibitor, HYDROLASE-INHIBITOR complex
Deposited on 2019-06-26, released 2019-09-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-12-18, with a file datestamp of 2019-12-13.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: N/A
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Acetylpolyamine amidohydrolase
    Species: Marinobacter subterrani [TaxId:1658765]
    Gene: Msub_13096
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6piaa1, d6piaa2
  • Chain 'B':
    Compound: Acetylpolyamine amidohydrolase
    Species: Marinobacter subterrani [TaxId:1658765]
    Gene: Msub_13096
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6piab1, d6piab2
  • Chain 'C':
    Compound: Acetylpolyamine amidohydrolase
    Species: Marinobacter subterrani [TaxId:1658765]
    Gene: Msub_13096
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6piac1, d6piac2
  • Chain 'D':
    Compound: Acetylpolyamine amidohydrolase
    Species: Marinobacter subterrani [TaxId:1658765]
    Gene: Msub_13096
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6piad1, d6piad2
  • Heterogens: XS6, ZN, K, MG, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6piaA (A:)
gplgsmktvfsplhsrrhvkteldgglliephekpsraetilarvkdqalgeilepeefg
lgpvkrvhtadyvsfletcwdewvaagkrgeaiptfwvgrgmrarlpkdidgrlgyyslg
adtsisdgtweaarasanvaltaqklvaegeraafalcrppghhahadvfggycffnnaa
iaaqafrdqgygkvavldvdfhhgngtqaifydrsdvltislhgdpdlvfphflgfedet
gegdgeaynlnivfppdtpfsiwsqglekacerirtfapdalvvalgvdtfeedpisffk
ltsgdylklgkrleqlglptvftmeggydvdaigvnavnvmqgfegks

    Sequence, based on observed residues (ATOM records): (download) 
    >6piaA (A:)
gsmktvfsplhsrrhvkteldgglliephekpsraetilarvkdqalgeilepeefglgp
vkrvhtadyvsfletcwdewvaagkrgeaiptfwvgrgmrarlpkdidgrlgyyslgadt
sisdgtweaarasanvaltaqklvaegeraafalcrppghhahadvfggycffnnaaiaa
qafrdqgygkvavldvdfhhgngtqaifydrsdvltislhgdpdlvfphflgfedetgeg
dgeaynlnivfppdtpfsiwsqglekacerirtfapdalvvalgvdtfeedpisffklts
gdylklgkrleqlglptvftmeggydvdaigvnavnvmqgfegks

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6piaB (B:)
gplgsmktvfsplhsrrhvkteldgglliephekpsraetilarvkdqalgeilepeefg
lgpvkrvhtadyvsfletcwdewvaagkrgeaiptfwvgrgmrarlpkdidgrlgyyslg
adtsisdgtweaarasanvaltaqklvaegeraafalcrppghhahadvfggycffnnaa
iaaqafrdqgygkvavldvdfhhgngtqaifydrsdvltislhgdpdlvfphflgfedet
gegdgeaynlnivfppdtpfsiwsqglekacerirtfapdalvvalgvdtfeedpisffk
ltsgdylklgkrleqlglptvftmeggydvdaigvnavnvmqgfegks

    Sequence, based on observed residues (ATOM records): (download) 
    >6piaB (B:)
gsmktvfsplhsrrhvkteldgglliephekpsraetilarvkdqalgeilepeefglgp
vkrvhtadyvsfletcwdewvaagkrgeaiptfwvgrgmrarlpkdidgrlgyyslgadt
sisdgtweaarasanvaltaqklvaegeraafalcrppghhahadvfggycffnnaaiaa
qafrdqgygkvavldvdfhhgngtqaifydrsdvltislhgdpdlvfphflgfedetgeg
dgeaynlnivfppdtpfsiwsqglekacerirtfapdalvvalgvdtfeedpisffklts
gdylklgkrleqlglptvftmeggydvdaigvnavnvmqgfegks

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6piaC (C:)
gplgsmktvfsplhsrrhvkteldgglliephekpsraetilarvkdqalgeilepeefg
lgpvkrvhtadyvsfletcwdewvaagkrgeaiptfwvgrgmrarlpkdidgrlgyyslg
adtsisdgtweaarasanvaltaqklvaegeraafalcrppghhahadvfggycffnnaa
iaaqafrdqgygkvavldvdfhhgngtqaifydrsdvltislhgdpdlvfphflgfedet
gegdgeaynlnivfppdtpfsiwsqglekacerirtfapdalvvalgvdtfeedpisffk
ltsgdylklgkrleqlglptvftmeggydvdaigvnavnvmqgfegks

    Sequence, based on observed residues (ATOM records): (download) 
    >6piaC (C:)
gsmktvfsplhsrrhvkteldgglliephekpsraetilarvkdqalgeilepeefglgp
vkrvhtadyvsfletcwdewvaagkrgeaiptfwvgrgmrarlpkdidgrlgyyslgadt
sisdgtweaarasanvaltaqklvaegeraafalcrppghhahadvfggycffnnaaiaa
qafrdqgygkvavldvdfhhgngtqaifydrsdvltislhgdpdlvfphflgfedetgeg
dgeaynlnivfppdtpfsiwsqglekacerirtfapdalvvalgvdtfeedpisffklts
gdylklgkrleqlglptvftmeggydvdaigvnavnvmqgfegks

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6piaD (D:)
gplgsmktvfsplhsrrhvkteldgglliephekpsraetilarvkdqalgeilepeefg
lgpvkrvhtadyvsfletcwdewvaagkrgeaiptfwvgrgmrarlpkdidgrlgyyslg
adtsisdgtweaarasanvaltaqklvaegeraafalcrppghhahadvfggycffnnaa
iaaqafrdqgygkvavldvdfhhgngtqaifydrsdvltislhgdpdlvfphflgfedet
gegdgeaynlnivfppdtpfsiwsqglekacerirtfapdalvvalgvdtfeedpisffk
ltsgdylklgkrleqlglptvftmeggydvdaigvnavnvmqgfegks

    Sequence, based on observed residues (ATOM records): (download) 
    >6piaD (D:)
gsmktvfsplhsrrhvkteldgglliephekpsraetilarvkdqalgeilepeefglgp
vkrvhtadyvsfletcwdewvaagkrgeaiptfwvgrgmrarlpkdidgrlgyyslgadt
sisdgtweaarasanvaltaqklvaegeraafalcrppghhahadvfggycffnnaaiaa
qafrdqgygkvavldvdfhhgngtqaifydrsdvltislhgdpdlvfphflgfedetgeg
dgeaynlnivfppdtpfsiwsqglekacerirtfapdalvvalgvdtfeedpisffklts
gdylklgkrleqlglptvftmeggydvdaigvnavnvmqgfegks