PDB entry 6peo

View 6peo on RCSB PDB site
Description: cryo-em structure of alpha-synuclein h50q narrow fibril
Deposited on 2019-06-20, released 2019-11-27
The last revision was dated 2019-11-27, with a file datestamp of 2019-11-22.
Experiment type: EM
Resolution: 3.3 Å
R-factor: N/A
AEROSPACI score: 0.1 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Alpha-synuclein
    Species: Homo sapiens [TaxId:9606]
    Gene: SNCA, NACP, PARK1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P37840
      • engineered mutation (49)
  • Chain 'B':
    Compound: Alpha-synuclein
    Species: Homo sapiens [TaxId:9606]
    Gene: SNCA, NACP, PARK1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P37840
      • engineered mutation (49)
  • Chain 'C':
    Compound: Alpha-synuclein
    Species: Homo sapiens [TaxId:9606]
    Gene: SNCA, NACP, PARK1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P37840
      • engineered mutation (49)
  • Chain 'D':
    Compound: Alpha-synuclein
    Species: Homo sapiens [TaxId:9606]
    Gene: SNCA, NACP, PARK1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P37840
      • engineered mutation (49)
  • Chain 'E':
    Compound: Alpha-synuclein
    Species: Homo sapiens [TaxId:9606]
    Gene: SNCA, NACP, PARK1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P37840
      • engineered mutation (49)

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6peoA (A:)
mdvfmkglskakegvvaaaektkqgvaeaagktkegvlyvgsktkegvvqgvatvaektk
eqvtnvggavvtgvtavaqktvegagsiaaatgfvkkdqlgkneegapqegiledmpvdp
dneayempseegyqdyepea

    Sequence, based on observed residues (ATOM records):
    >6peoA (A:)
gvlyvgsktkegvvqgvatvaektkeqvtnvggavvtgvtavaqktvegagsiaaatgfv
kkdq

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6peoB (B:)
mdvfmkglskakegvvaaaektkqgvaeaagktkegvlyvgsktkegvvqgvatvaektk
eqvtnvggavvtgvtavaqktvegagsiaaatgfvkkdqlgkneegapqegiledmpvdp
dneayempseegyqdyepea

    Sequence, based on observed residues (ATOM records):
    >6peoB (B:)
gvlyvgsktkegvvqgvatvaektkeqvtnvggavvtgvtavaqktvegagsiaaatgfv
kkdq

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6peoC (C:)
mdvfmkglskakegvvaaaektkqgvaeaagktkegvlyvgsktkegvvqgvatvaektk
eqvtnvggavvtgvtavaqktvegagsiaaatgfvkkdqlgkneegapqegiledmpvdp
dneayempseegyqdyepea

    Sequence, based on observed residues (ATOM records):
    >6peoC (C:)
gvlyvgsktkegvvqgvatvaektkeqvtnvggavvtgvtavaqktvegagsiaaatgfv
kkdq

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6peoD (D:)
mdvfmkglskakegvvaaaektkqgvaeaagktkegvlyvgsktkegvvqgvatvaektk
eqvtnvggavvtgvtavaqktvegagsiaaatgfvkkdqlgkneegapqegiledmpvdp
dneayempseegyqdyepea

    Sequence, based on observed residues (ATOM records):
    >6peoD (D:)
gvlyvgsktkegvvqgvatvaektkeqvtnvggavvtgvtavaqktvegagsiaaatgfv
kkdq

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6peoE (E:)
mdvfmkglskakegvvaaaektkqgvaeaagktkegvlyvgsktkegvvqgvatvaektk
eqvtnvggavvtgvtavaqktvegagsiaaatgfvkkdqlgkneegapqegiledmpvdp
dneayempseegyqdyepea

    Sequence, based on observed residues (ATOM records):
    >6peoE (E:)
gvlyvgsktkegvvqgvatvaektkeqvtnvggavvtgvtavaqktvegagsiaaatgfv
kkdq