PDB entry 6pdp

View 6pdp on RCSB PDB site
Description: human pim1 bound to benzothiophene inhibitor 379
Deposited on 2019-06-19, released 2019-07-24
The last revision was dated 2020-01-01, with a file datestamp of 2019-12-27.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein kinase pim-1
    Species: Homo sapiens [TaxId:9606]
    Gene: PIM1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P11309
      • conflict (250)
  • Chain 'B':
    Compound: peptide
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 6PDP
  • Heterogens: OBY, SO4, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6pdpA (A:)
smllskinslahlraapcndlhatklapgkekeplesqyqvgpllgsggfgsvysgirvs
dnlpvaikhvekdrisdwgelpngtrvpmevvllkkvssgfsgvirlldwferpdsfvli
lerpepvqdlfdfitergalqeelarsffwqvleavrhchncgvlhrdikdenilidlnr
gelklidfgsgallkdtvytdfdgtrvysppewiryhryhgrsaavwslgillydmvcgd
ipfehdeeiiggqvffrqrvssecqhlirwclalrpsdrptfeeiqnhpwmqdvllpqet
aeihlhslspgps

    Sequence, based on observed residues (ATOM records):
    >6pdpA (A:)
sqyqvgpllggfgsvysgirvsdnlpvaikhvekdrisdwgelpngtrvpmevvllkkvs
sgfsgvirlldwferpdsfvlilerpepvqdlfdfitergalqeelarsffwqvleavrh
chncgvlhrdikdenilidlnrgelklidfgsgallkdtvytdfdgtrvysppewiryhr
yhgrsaavwslgillydmvcgdipfehdeeiiggqvffrqrvssecqhlirwclalrpsd
rptfeeiqnhpwmqdvllpqetaeihlh

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6pdpB (B:)
arkrrrhpsgppta

    Sequence, based on observed residues (ATOM records):
    >6pdpB (B:)
krrrhps