PDB entry 6pdj

View 6pdj on RCSB PDB site
Description: Tyrosine-protein kinase LCK bound to Compound 11
Class: signaling protein/inhibitor
Keywords: inhibitor, SIGNALING PROTEIN, SIGNALING PROTEIN-INHIBITOR complex
Deposited on 2019-06-19, released 2019-10-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-10-30, with a file datestamp of 2019-10-25.
Experiment type: XRAY
Resolution: 1.81 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tyrosine-protein kinase Lck
    Species: Homo sapiens [TaxId:9606]
    Gene: LCK
    Database cross-references and differences (RAF-indexed):
    • Uniprot P06239 (3-End)
      • expression tag (0-2)
    Domains in SCOPe 2.08: d6pdja1, d6pdja2
  • Heterogens: ODJ, CXS, SO4, NI, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6pdjA (A:)
    ghmqtqkpqkpwwedewevpretlklverlgagqfgevwmgyynghtkvavkslkqgsms
    pdaflaeanlmkqlqhqrlvrlyavvtqepiyiiteymengslvdflktpsgikltinkl
    ldmaaqiaegmafieernyihrdlraanilvsdtlsckiadfglarliedneytaregak
    fpikwtapeainygtftiksdvwsfgillteivthgripypgmtnpeviqnlergyrmvr
    pdncpeelyqlmrlcwkerpedrptfdylrsvledfftategqyqpqp
    

    Sequence, based on observed residues (ATOM records): (download)
    >6pdjA (A:)
    ghmqkpwwedewevpretlklverlgagqfgevwmgyynghtkvavkslkqgsmspdafl
    aeanlmkqlqhqrlvrlyavvtqepiyiiteymengslvdflktpsgikltinklldmaa
    qiaegmafieernyihrdlraanilvsdtlsckiadfglarliedneytaregakfpikw
    tapeainygtftiksdvwsfgillteivthgripypgmtnpeviqnlergyrmvrpdncp
    eelyqlmrlcwkerpedrptfdylrsvledffta