PDB entry 6pdc

View 6pdc on RCSB PDB site
Description: Crystal structure of MYST acetyltransferase domain in complex with inhibitor 42
Class: transferase/transferase inhibitor
Keywords: Inhibitor, Complex, MYST, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2019-06-18, released 2020-04-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-05-27, with a file datestamp of 2020-05-22.
Experiment type: XRAY
Resolution: 1.96 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Histone acetyltransferase KAT8
    Species: Homo sapiens [TaxId:9606]
    Gene: KAT8, MOF, MYST1, PP7073
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9H7Z6 (0-271)
      • conflict (72)
      • engineered mutation (138)
      • engineered mutation (141-142)
      • engineered mutation (153)
      • engineered mutation (190)
      • conflict (195)
    Domains in SCOPe 2.08: d6pdca_
  • Heterogens: O9P, ZN, NA, GOL, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6pdcA (A:)
kyvdkihignyeidawyfspfpedygkqpklwlceyclkymkyeksyrfhlgqcqwrqpp
gkeiyrksnisvhevdgkdhkiycqnlcllaklfldhktlyfdvepfvfyiltevdrqga
hivgyfskekespdgnnvscimilppyqrrgygrfliafsyelsklestvgspekplsdl
gklsyrsywssvllenlrdfrgtlsikdlsqmtsitqndiistlqslnmvkywkgqhvic
vtpklveehlksaqykkppitvdsvclkwapp

    Sequence, based on observed residues (ATOM records): (download) 
    >6pdcA (A:)
kyvdkihignyeidawyfspfpedygkqpklwlceyclkymkyeksyrfhlgqcqwrqpp
gkeiyrksnisvhevdgkdhkiycqnlcllaklfldhktlyfdvepfvfyiltevdrqga
hivgyfskekespdgnnvscimilppyqrrgygrfliafsyelsklestvgspekplsdl
gklsyrsywssvllenlrdlsikdlsqmtsitqndiistlqslnmvkywkgqhvicvtpk
lveehlksaqykkppitvdsvclkwapp