PDB entry 6pcv

View 6pcv on RCSB PDB site
Description: single particle reconstruction of phosphatidylinositol (3,4,5) trisphosphate-dependent rac exchanger 1 bound to g protein beta gamma subunits
Deposited on 2019-06-18, released 2019-10-23
The last revision was dated 2019-12-04, with a file datestamp of 2019-11-29.
Experiment type: EM
Resolution: 3.2 Å
R-factor: N/A
AEROSPACI score: 0.11 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Phosphatidylinositol (3,4,5) trisphosphate-dependent Rac exchanger 1
    Species: Homo sapiens [TaxId:9606]
    Gene: PREX1
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
    Species: Bos taurus [TaxId:9913]
    Gene: GNB1
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
    Species: Bos taurus [TaxId:9913]
    Gene: GNG2
    Database cross-references and differences (RAF-indexed):

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6pcvA (A:)
gefaaareserqlrlrlcvlneilgterdyvgtlrflqsaflhrirqnvadsvekgltee
nvkvlfsniedilevhkdflaaleyclhpepqsqhelgnvflkfkdkfcvyeeycsnhek
alrllvelnkiptvrafllscmllggrkttdiplegyllspiqrickyplllkelakrtp
gkhpdhpavqsalqamktvcsninetkrqmeklealeqlqshiegwegsnltdictqlll
qgtllkisagniqerafflfdnllvyckrksrvtgskkstkrtksingslyifrgrinte
vmevenvedgtadyhsngytvtngwkihntaknkwfvcmaktaeekqkwldaiirereqr
eslklgmerdayvmiaekgeklyhmmmnkkvnlikdrrrklstvpkcflgnefvawllei
geiskteegvnlgqallengiihhvsdkhqfkneqvmyrfryddgtykarseledimskg
vrlycrlhslytpvikdrdyhlktyksvlpgsklvdwllaqgdcqtreeavalgvglcnn
gfmhhvleksefrdesqyfrfhadeemegtssknkqlrndfklvenilakrllilpqeed
ygfdieeknkavvvksvqrgslaevaglqvgrkiysinedlvflrpfsevesilnqsfcs
rrplrllvatkakeiikipdqpdtlcfqirgaappyvyavgrgseamaaglcagqcilkv
ngsnvmndgapevlehfqafrsrreealglyqwiyhthedaqearasqeastedpsgeqa
qeedqadsafpllslgprlslcedspmvtltvdnvhlehgvvyeyvstagvrchvlekiv
eprgcfgltakileafaandsvfvencrrlmalssaivtmphfefrnicdtklesigqri
acyqefaaqlksrvsppfkqaplephplcgldfcptnchinlmevsypkttpsvgrsfsi
rfgrkpsligldpeqghlnpmsytqhcittmaapswkclpaaegdpqgqglhdgsfgpas
gtlgqedrglsfllkqedreiqdaylqlftkldvalkemkqyvtqinrllstiteptsgg
scdaslaeeasslplvseesemdrsdhggikkvcfkvaeedqedsghdtmsyrdsysecn
snrdsvlsytsvrsnssylgsdemgsgdelpcdmripsdkqdklhgclehlfnqvdsina
llkgpvmsrafeetkhfpmnhslqefkqkeectirgrsliqisiqedpwnlpnsiktlvd
niqryvedgknqlllallkctdtelqlrrdaifcqalvaavctfseqllaalgyrynnng
eyeessrdasrkwleqvaatgvllhcqsllspatvkeertmlediwvtlseldnvtfsfk
qldenyvantnvfyhiegsrqalkvifyldsyhfsklpsrleggaslrlhtalftkvlen
veglpspgsqaaedlqqdinaqslekvqqyyrklrafylersnlptdasttavkidqlir
pinaldelcrlmksfvhpkpgaagsvgaglipisselcyrlgacqmvmcgtgmqrstlsv
sleqaailarshgllpkcimqatdimrkqgprveilaknlrvkdqmpqgaprlyrlcqpp
vdgdlhhhhhhhhhh

    Sequence, based on observed residues (ATOM records):
    >6pcvA (A:)
eledimskgvrlycrlhslytpvikdrdyhlktyksvlpgsklvdwllaqgdcqtreeav
algvglcnngfmhhvleksefrdesqyfrfhadeemegtqlrndfklvenilakrllilp
qeedygfdieeknkavvvksvqrgslaevaglqvgrkiysinedlvflrpfsevesilnq
sfcsrrplrllvatkakeiikipdqpdtlcfqirgaappyvyavgrgseamaaglcagqc
ilkvngsnvmndgapevlehfqafrsrreealglyqwiyhthedaqearasqedspmvtl
tvdnvhlehgvvyeyvstagvrchvlekiveprgcfgltakileafaandsgqriacyqe
faaqlksrvsppfkqaplephplcgldfcptnchinlmevsypklnpmsytqhcittmaa
pswkcelqlrrdaifcqalvaavctfseqllaalgyrynnngeyeessrdasrkwleqva
atgvllhcqsllspatvkeertmlediwvtlseldnvtfsfkqldenyvantnvfyhieg
srqalkvifyldsyhfsklpsrleggaslrlhtalftkvlenveglpspgsqaaedlqqd
inaqslekvqqyyrklrafylersnlvkidqlirpinaldelcrlmksfvhpkpgaagsv
gaglipisselcyrlgacqmvmcgtgmqrstlsvsleqaailarshgllpkcimqatdim
rkqgprveilaknlrvkdqmpqgaprlyrlcqpp

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6pcvB (B:)
mseldqlrqeaeqlknqirdarkacadatlsqitnnidpvgriqmrtrrtlrghlakiya
mhwgtdsrllvsasqdgkliiwdsyttnkvhaiplrsswvmtcayapsgnyvacggldni
csiynlktregnvrvsrelaghtgylsccrflddnqivtssgdttcalwdietgqqtttf
tghtgdvmslslapdtrlfvsgacdasaklwdvregmcrqtftghesdinaicffpngna
fatgsddatcrlfdlradqelmtyshdniicgitsvsfsksgrlllagyddfncnvwdal
kadragvlaghdnrvsclgvtddgmavatgswdsflkiwn

    Sequence, based on observed residues (ATOM records):
    >6pcvB (B:)
seldqlrqeaeqlknqirdarkacadatlsqitnnidpvgriqmrtrrtlrghlakiyam
hwgtdsrllvsasqdgkliiwdsyttnkvhaiplrsswvmtcayapsgnyvacggldnic
siynlktregnvrvsrelaghtgylsccrflddnqivtssgdttcalwdietgqqtttft
ghtgdvmslslapdtrlfvsgacdasaklwdvregmcrqtftghesdinaicffpngnaf
atgsddatcrlfdlradqelmtyshdniicgitsvsfsksgrlllagyddfncnvwdalk
adragvlaghdnrvsclgvtddgmavatgswdsflkiwn

  • Chain 'G':
    Sequence, based on SEQRES records:
    >6pcvG (G:)
hhhhhhhhhhmasnntasiaqarklveqlkmeanidrikvskaaadlmayceahakedpl
ltpvpasenpfrekkffsail

    Sequence, based on observed residues (ATOM records):
    >6pcvG (G:)
ntasiaqarklveqlkmeanidrikvskaaadlmayceahakedplltpvpasenpfrek
kf