PDB entry 6pbj

View 6pbj on RCSB PDB site
Description: The structure of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase with Gly190Pro mutation
Class: transferase
Keywords: DAH7PS, Allostery, shipmate pathway, TIM barrel, TRANSFERASE
Deposited on 2019-06-13, released 2020-04-08
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-10-21, with a file datestamp of 2020-10-16.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: phospho-2-dehydro-3-deoxyheptonate aldolase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: aroG_1, ERS027644_03091, ERS031537_02142, ERS124361_01166
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A0T9FW33 (2-463)
      • expression tag (0-1)
      • engineered mutation (191)
    Domains in SCOPe 2.08: d6pbja1, d6pbja2
  • Chain 'B':
    Compound: phospho-2-dehydro-3-deoxyheptonate aldolase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: aroG_1, ERS027644_03091, ERS031537_02142, ERS124361_01166
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A0T9FW33 (2-463)
      • expression tag (0-1)
      • engineered mutation (191)
    Domains in SCOPe 2.08: d6pbjb1, d6pbjb2
  • Heterogens: PO4, SO4, MN, CL, PEG, PG4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6pbjA (A:)
gamnwtvdipidqlpslpplptdlrtrldaalakpaaqqptwpadqalamrtvlesvppv
tvpseivrlqeqlaqvakgeafllqggdcaetfmdntephirgnvrallqmavvltygas
mpvvkvariagqyakprsadidalglrsyrgdmingfapdaaarehdpsrlvrayanasa
amnlvraltssplaslhlvhdwnrefvrtspagaryealateidrglrfmsacgvadrnl
qtaeiyashealvldyeramlrlsdgddgepqlfdlsahtvwigertrqidgahiafaqv
ianpvgvklgpnmtpelaveyverldphnkpgrltlvsrmgnhkvrdllppivekvqatg
hqviwqcdpmhgnthesstgfktrhfdrivdevqgffevhralgthpggihveitgenvt
eclggaqdisetdlagryetacdprlntqqslelaflvaemlrd

    Sequence, based on observed residues (ATOM records): (download) 
    >6pbjA (A:)
gamnwtvdipidqlpslpplptdlrtrldaalakpaaqqptwpadqalamrtvlesvppv
tvpseivrlqeqlaqvakgeafllqggdcaetfmdntephirgnvrallqmavvltygas
mpvvkvariagqyakprsadidalglrsyrgdmingfapdaaarehdpsrlvrayanasa
amnlvraltssplaslhlvhdwnrefvrtspagaryealateidrglrfmsacgvadrnl
qtaeiyashealvldyeramlrlsdgepqlfdlsahtvwigertrqidgahiafaqvian
pvgvklgpnmtpelaveyverldphnkpgrltlvsrmgnhkvrdllppivekvqatghqv
iwqcdpmhgntrhfdrivdevqgffevhralgthpggihveitgenvteclggaqdiset
acdprlntqqslelaflvaemlrd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6pbjB (B:)
gamnwtvdipidqlpslpplptdlrtrldaalakpaaqqptwpadqalamrtvlesvppv
tvpseivrlqeqlaqvakgeafllqggdcaetfmdntephirgnvrallqmavvltygas
mpvvkvariagqyakprsadidalglrsyrgdmingfapdaaarehdpsrlvrayanasa
amnlvraltssplaslhlvhdwnrefvrtspagaryealateidrglrfmsacgvadrnl
qtaeiyashealvldyeramlrlsdgddgepqlfdlsahtvwigertrqidgahiafaqv
ianpvgvklgpnmtpelaveyverldphnkpgrltlvsrmgnhkvrdllppivekvqatg
hqviwqcdpmhgnthesstgfktrhfdrivdevqgffevhralgthpggihveitgenvt
eclggaqdisetdlagryetacdprlntqqslelaflvaemlrd

    Sequence, based on observed residues (ATOM records): (download) 
    >6pbjB (B:)
gamnwtvdipidpplptdlrtrldaalakpaaqqptwpadqalamrtvlesvppvtvpse
ivrlqeqlaqvakgeafllqggdcaetfmdntephirgnvrallqmavvltygasmpvvk
variagqyakprsadidalglrsyrgdmingfapdaaarehdpsrlvrayanasaamnlv
raltssplaslhlvhdwnrefvrtspagaryealateidrglrfmsacgvadrnlqtaei
yashealvldyeramlrlsddgepqlfdlsahtvwigertrqidgahiafaqvianpvgv
klgpnmtpelaveyverldphnkpgrltlvsrmgnhkvrdllppivekvqatghqviwqc
dpmhgnrhfdrivdevqgffevhralgthpggihveilntqqslelaflvaemlrd