PDB entry 6p94

View 6p94 on RCSB PDB site
Description: human ape1 c65a ap-endonuclease product complex
Deposited on 2019-06-09, released 2020-01-01
The last revision was dated 2020-02-26, with a file datestamp of 2020-02-21.
Experiment type: XRAY
Resolution: 2.09 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA-(apurinic or apyrimidinic site) lyase
    Species: Homo sapiens [TaxId:9606]
    Gene: APEX1, APE, APE1, APEX, APX, HAP1, REF1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P27695 (0-275)
      • conflict (22)
  • Chain 'B':
    Compound: DNA-(apurinic or apyrimidinic site) lyase
    Species: Homo sapiens [TaxId:9606]
    Gene: APEX1, APE, APE1, APEX, APX, HAP1, REF1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P27695 (0-275)
      • conflict (22)
  • Chain 'D':
    Compound: DNA (5'-d(p*(3dr)p*cp*gp*ap*cp*gp*gp*ap*tp*cp*c)-3')
    Species: synthetic construct, synthetic [TaxId:32630]
  • Chain 'P':
    Compound: DNA (5'-d(*gp*cp*tp*gp*ap*tp*gp*cp*gp*c)-3')
    Species: synthetic construct, synthetic [TaxId:32630]
  • Chain 'V':
    Compound: DNA (5'-d(*gp*gp*ap*tp*cp*cp*gp*tp*cp*gp*gp*gp*cp*gp*cp*ap*tp*cp*ap*gp*c)-3')
    Species: synthetic construct, synthetic [TaxId:32630]
  • Heterogens: MG, PEG, CL, EDO, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records:
    >6p94A (A:)
    alyedppdqktspsgkpatlkiaswnvdglrawikkkgldwvkeeapdilclqetkcsen
    klpaelqelpglshqywsapsdkegysgvgllsrqcplkvsygigdeehdqegrvivaef
    dsfvlvtayvpnagrglvrleyrqrwdeafrkflkglasrkplvlcgdlnvaheeidlrn
    pkgnkknagftpqerqgfgellqavpladsfrhlypntpyaytfwtymmnarsknvgwrl
    dyfllshsllpalcdskirskalgsdhcpitlylal
    

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6p94B (B:)
    alyedppdqktspsgkpatlkiaswnvdglrawikkkgldwvkeeapdilclqetkcsen
    klpaelqelpglshqywsapsdkegysgvgllsrqcplkvsygigdeehdqegrvivaef
    dsfvlvtayvpnagrglvrleyrqrwdeafrkflkglasrkplvlcgdlnvaheeidlrn
    pkgnkknagftpqerqgfgellqavpladsfrhlypntpyaytfwtymmnarsknvgwrl
    dyfllshsllpalcdskirskalgsdhcpitlylal
    

    Sequence, based on observed residues (ATOM records):
    >6p94B (B:)
    alyedppdqktspsgkpatlkiaswnvdglrawikkkgldwvkeeapdilclqetkcsen
    klpaelqelpglshqywsapsysgvgllsrqcplkvsygigdegrvivaefdsfvlvtay
    vpnagrglvrleyrqrwdeafrkflkglasrkplvlcgdlnvaheeidlrnpkgnkknag
    ftpqerqgfgellqavpladsfrhlypntpyaytfwtymmnarsknvgwrldyfllshsl
    lpalcdskirskalgsdhcpitlylal
    

  • Chain 'D':
    No sequence available.

  • Chain 'P':
    No sequence available.

  • Chain 'V':
    No sequence available.