PDB entry 6p90

View 6p90 on RCSB PDB site
Description: Crystal structure of PaDHDPS2-H56Q mutant
Class: structural protein
Keywords: Allosteric regulation, antibiotic resistance, diaminopimelate, 4-hydroxy-tetrahydrodipicolinate synthase, lysine biosynthesis, STRUCTURAL PROTEIN
Deposited on 2019-06-08, released 2019-08-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-02-05, with a file datestamp of 2020-01-31.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 4-hydroxy-tetrahydrodipicolinate synthase
    Species: Pseudomonas aeruginosa [TaxId:287]
    Gene: dapA, PA1010
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9I4W3 (0-End)
      • engineered mutation (55)
    Domains in SCOPe 2.08: d6p90a_
  • Chain 'B':
    Compound: 4-hydroxy-tetrahydrodipicolinate synthase
    Species: Pseudomonas aeruginosa [TaxId:287]
    Gene: dapA, PA1010
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9I4W3 (0-End)
      • engineered mutation (55)
    Domains in SCOPe 2.08: d6p90b_
  • Heterogens: GOL, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6p90A (A:)
miagsmvalvtpfdaqgrldwdslaklvdfhlqegtnaivavgttgesatldveeqiqvi
rrvvdqvkgripviagtganstreavalteaaksggadacllvtpyynkptqegmyqhfr
hiaeavaipqilynvpgrtscdmlpetverlskvpniigikeatgdlqrakeviervgkd
flvysgddatavelmllggkgnisvtanvapramsdlcaaamrgdaaaaraindrlmplh
kalfiesnpipvkwalhemglipegirlpltwlsprcheplrqamrqtgvla

    Sequence, based on observed residues (ATOM records): (download) 
    >6p90A (A:)
miagsmvalvtpfdaqgrldwdslaklvdfhlqegtnaivavgttgesatldveeqiqvi
rrvvdqvkgripviagtganstreavalteaaksggadacllvtpyynkptqegmyqhfr
hiaeavaipqilynvpgrtscdmlpetverlskvpniigikeatgdlqrakeviervgkd
flvysgddatavelmllggkgnisvtanvapramsdlcaaamrgdaaaaraindrlmplh
kalfiesnpipvkwalhemglipegirlpltwlsprcheplrqamrqtgvl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6p90B (B:)
miagsmvalvtpfdaqgrldwdslaklvdfhlqegtnaivavgttgesatldveeqiqvi
rrvvdqvkgripviagtganstreavalteaaksggadacllvtpyynkptqegmyqhfr
hiaeavaipqilynvpgrtscdmlpetverlskvpniigikeatgdlqrakeviervgkd
flvysgddatavelmllggkgnisvtanvapramsdlcaaamrgdaaaaraindrlmplh
kalfiesnpipvkwalhemglipegirlpltwlsprcheplrqamrqtgvla

    Sequence, based on observed residues (ATOM records): (download) 
    >6p90B (B:)
miagsmvalvtpfdaqgrldwdslaklvdfhlqegtnaivavgttgesatldveeqiqvi
rrvvdqvkgripviagtganstreavalteaaksggadacllvtpyynkptqegmyqhfr
hiaeavaipqilynvpgrtscdmlpetverlskvpniigikeatgdlqrakeviervgkd
flvysgddatavelmllggkgnisvtanvapramsdlcaaamrgdaaaaraindrlmplh
kalfiesnpipvkwalhemglipegirlpltwlsprcheplrqamrqtgvl