PDB entry 6p7f

View 6p7f on RCSB PDB site
Description: Human ABCC6 NBD2 R1459D mutant in Apo state
Class: transport protein
Keywords: ABCC6, NBD2, Apo state, ATP-Binding Cassette transporter C6, nucleotide binding domain 2, TRANSPORT PROTEIN
Deposited on 2019-06-05, released 2020-06-10
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-06-10, with a file datestamp of 2020-06-05.
Experiment type: XRAY
Resolution: 2.85 Å
R-factor: N/A
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Multidrug resistance-associated protein 6
    Species: Homo sapiens [TaxId:9606]
    Gene: ABCC6, ARA, MRP6
    Database cross-references and differences (RAF-indexed):
    • Uniprot O95255 (Start-249)
      • engineered mutation (205)
    Domains in SCOPe 2.07: d6p7fa_
  • Heterogens: SO4

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6p7fA (A:)
aaqppwpqggqiefrdfglryrpelplavqgvsfkihagekvgivgrtgagksslasgll
rlqeaaeggiwidgvpiahvglhtlrsrisiipqdpilfpgslrmnldllqehsdeaiwa
aletvqlkalvaslpgqlqykcadrgedlsvgqkqllclarallrktqilildeataavd
pgtelqmqamlgswfaqctvlliahdlrsvmdcarvlvmdkgqvaesgspaqllaqkglf
yrlaqesglv

    Sequence, based on observed residues (ATOM records): (download) 
    >6p7fA (A:)
aqppwpqggqiefrdfglryrpelplavqgvsfkihagekvgivgrtgagksslasgllr
lqeaaeggiwidgvpiahvglhtlrsrisiipqdpilfpgslrmnldllqehsdeaiwaa
letvqlkalvaslpgqlqykcargedlsvgqkqllclarallrktqilildeataavdpg
telqmqamlgswfaqctvlliahdlrsvmdcarvlvmdkgqvaesgspaqllaqkglfyr
laqesglv