PDB entry 6p70

View 6p70 on RCSB PDB site
Description: x-ray crystal structure of bacterial rna polymerase and pyrbi promoter complex
Deposited on 2019-06-04, released 2019-06-19
The last revision was dated 2020-03-11, with a file datestamp of 2020-03-06.
Experiment type: XRAY
Resolution: 3.05 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA-directed RNA polymerase subunit alpha
    Species: Thermus thermophilus [TaxId:274]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: DNA-directed RNA polymerase subunit alpha
    Species: Thermus thermophilus [TaxId:274]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: DNA-directed RNA polymerase subunit beta
    Species: Thermus thermophilus [TaxId:274]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: DNA-directed RNA polymerase subunit beta'
    Species: Thermus thermophilus [TaxId:274]
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: DNA-directed RNA polymerase subunit omega
    Species: Thermus thermophilus [TaxId:274]
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: RNA polymerase sigma factor SigA
    Species: Thermus thermophilus [TaxId:274]
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: DNA (5'-d(p*tp*cp*cp*cp*gp*gp*cp*ap*ap*ap*tp*tp*gp*tp*cp*cp*g)-3')
    Species: Escherichia coli, synthetic [TaxId:562]
  • Chain 'H':
    Compound: DNA (5'-d(*tp*ap*tp*ap*ap*tp*cp*gp*ap*tp*cp*tp*tp*tp*gp*cp*cp*gp*gp*g)-3')
    Species: Escherichia coli, synthetic [TaxId:562]
  • Heterogens: MG, ZN

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6p70A (A:)
mldsklkapvftvrtqgreygefvleplergfgvtlgnplrrillssipgtavtsvyied
vlhefstipgvkedvveiilnlkelvvrflnpslqtvtlllkaegpkevkardflpvadv
eimnpdlhiatleeggrlnmevrvdrgvgyvpaekhgikdrinaipvdavfspvrrvafq
vedtrlgqrtdldkltlriwtdgsvtplealnqaveilrehltyfsnpqaaavaapeeak
epeappeqeeeldlpleelglstrvlhslkeegiesvrallalnlkdlknipgigersle
eikealekkgftlke

    Sequence, based on observed residues (ATOM records):
    >6p70A (A:)
sklkapvftvrtqgreygefvleplergfgvtlgnplrrillssipgtavtsvyiedvlh
efstipgvkedvveiilnlkelvvrflnpslqtvtlllkaegpkevkardflpvadveim
npdlhiatleeggrlnmevrvdrgvgyvpaekhgikdrinaipvdavfspvrrvafqved
trlgqrtdldkltlriwtdgsvtplealnqaveilrehltyfsnpq

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6p70B (B:)
mldsklkapvftvrtqgreygefvleplergfgvtlgnplrrillssipgtavtsvyied
vlhefstipgvkedvveiilnlkelvvrflnpslqtvtlllkaegpkevkardflpvadv
eimnpdlhiatleeggrlnmevrvdrgvgyvpaekhgikdrinaipvdavfspvrrvafq
vedtrlgqrtdldkltlriwtdgsvtplealnqaveilrehltyfsnpqaaavaapeeak
epeappeqeeeldlpleelglstrvlhslkeegiesvrallalnlkdlknipgigersle
eikealekkgftlke

    Sequence, based on observed residues (ATOM records):
    >6p70B (B:)
kapvftvrtqgreygefvleplergfgvtlgnplrrillssipgtavtsvyiedvlhefs
tipgvkedvveiilnlkelvvrflnpslqtvtlllkaegpkevkardflpvadveimnpd
lhiatleeggrlnmevrvdrgvgyvpaekhgikdrinaipvdavfspvrrvafqvedtrl
gqrtdldkltlriwtdgsvtplealnqaveilrehltyfsnp

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6p70C (C:)
meikrfgrireviplpplteiqvesyrralqadvppekrenvgiqaafretfpieeedkg
kgglvldfleyrlgeppfpqdecrekdltyqaplyarlqlihkdtglikedevflghipl
mtedgsfiingadrvivsqihrspgvyftpdparpgryiasiiplpkrgpwidlevepng
vvsmkvnkrkfplvlllrvlgydqetlarelgaygelvqglmdesvfamrpeealirlft
llrpgdppkrdkavayvygliadprrydlgeagrykaeeklgirlsgrtlarfedgefkd
evflptlrylfaltagvpghevddidhlgnrrirtvgelmtdqfrvglarlargvrerml
mgsedsltpaklvnsrpleaaireffsrsqlsqfkdetnplsslrhkrrisalgpggltr
eragfdvrdvhrthygricpvetpeganiglitslaayarvdelgfirtpyrrvvggvvt
devvymtateedrytiaqantplegnriaaervvarrkgepvivspeevefmdvspkqvf
svntnlipflehddanralmgsnmqtqavpliraqapvvmtgleervvrdslaalyaeed
gevakvdgnrivvryedgrlveyplrrfyrsnqgtaldqrprvvvgqrvrkgdlladgpa
sengflalgqnvlvaimpfdgynfedaiviseellkrdfytsihieryeieardtklgpe
ritrdiphlseaalrdldeegvvrigaevkpgdilvgrtsfkgeseptpeerllrsifge
kardvkdtslrvppgeggivvrtvrlrrgdpgvelkpgvrevvrvyvaqkrklqvgdkla
nrhgnkgvvakilpvedmphlpdgtpvdvilnplgvpsrmnlgqilethlglagyflgqr
yispifdgakepeikellaqafevyfgkrkgegfgvdkrevevlrraeklglvtpgktpe
eqlkelflqgkvvlydgrtgepiegpivvgqmfimklyhmvedkmharstgpyslitqqp
lggkaqfggqrfgemevwaleaygaahtlqemltlksddiegrnaayeaiikgedvpeps
vpesfrvlvkelqalaldvqtldekdnpvdifeglaskr

    Sequence, based on observed residues (ATOM records):
    >6p70C (C:)
meikrfgrireviplpplteiqvesyrralqadvppekrenvgiqaafretfpieelvld
fleyrlgeppfpqdecrekdltyqaplyarlqlihkdtglikedevflghiplmtedgsf
iingadrvivsqihrspgvyftpdparpgryiasiiplpkrgpwidlevepngvvsmkvn
krkfplvlllrvlgydqetlarelgaygelvqglmdesvfamrpeealirlftllrpgdp
pkrdkavayvygliadprrydlgeagrykaeeklgirlsgrtlarfedgefkdevflptl
rylfaltagvpghevddidhlgnrrirtvgelmtdqfrvglarlargvrermlmgsedsl
tpaklvnsrpleaaireffsrsqlsqfkdetnplsslrhkrrisalgpggltreragfdv
rdvhrthygricpvetpeganiglitslaayarvdelgfirtpyrrvvggvvtdevvymt
ateedrytiaqantplegnriaaervvarrkgepvivspeevefmdvspkqvfsvntnli
pflehddanralmgsnmqtqavpliraqapvvmtgleervvrdslaalyaeedgevakvd
gnrivvryedgrlveyplrrfyrsnqgtaldqrprvvvgqrvrkgdlladgpasengfla
lgqnvlvaimpfdgynfedaiviseellkrdfytsihieryeieardtklgperitrdip
hlseaalrdldeegvvrigaevkpgdilvgrtsfkgeseptpeerllrsifgekardvkd
tslrvppgeggivvrtvrlrrgdpgvelkpgvrevvrvyvaqkrklqvgdklanrhgnkg
vvakilpvedmphlpdgtpvdvilnplgvpsrmnlgqilethlglagyflgqryispifd
gakepeikellaqafevyfgkrkgegfgvdkrevevlrraeklglvtpgktpeeqlkelf
lqgkvvlydgrtgepiegpivvgqmfimklyhmvedkmharstgpyslitqqplggkaqf
ggqrfgemevwaleaygaahtlqemltlksddiegrnaayeaiikgedvpepsvpesfrv
lvkelqalaldvqtldekdnpvdifeglask

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6p70D (D:)
mkkevrkvrialaspekirswsygevekpetinyrtlkperdglfderifgpikdyecac
gkykrqrfegkvcercgvevtksivrryrmghielatpaahiwfvkdvpskigtlldlsa
teleqvlyfskyivldpkgailngvpvekrqlltdeeyrelrygkqetyplppgvdalvk
dgeevvkgqelapgvvsrldgvalyrfprrvrveyvkkeraglrlplaawvekeaykpge
ilaelpepylfraeeegvvelkeleegaflvlrredepvatyflpvgmtplvvhgeivek
gqplaeakgllrmprqvraaqveaeeegetvyltlflewtepkdyrvqphmnvvvpegar
veagdkivaaidpeeeviaeaegvvhlhepasilvvkarvypfeddvevstgdrvapgdv
ladggkvksdvygrvevdlvrnvvrvvesydidarmgaeaiqqllkeldlealekellee
mkhpsrarrakarkrlevvrafldsgnrpewmileavpvlppdlrpmvqvdggrfatsdl
ndlyrrlinrnnrlkkllaqgapeiiirnekrmlqeavdalldngrrgapvtnpgsdrpl
rsltdilsgkqgrfrqnllgkrvdysgrsvivvgpqlklhqcglpkrmalelfkpfllkk
meekgiapnvkaarrmlerqrdikdevwdaleevihgkvvllnraptlhrlgiqafqpvl
vegqsiqlhplvceafnadfdgdqmavhvplssfaqaeariqmlsahnllspasgeplak
psrdiilglyyitqvrkekkgaglefatpeealaahergevalnapikvagretsvgrlk
yvfanpdeallavahgivdlqdvvtvrymgkrletspgrilfarivaeavedekvaweli
qldvpqeknslkdlvyqaflrlgmektarlldalkyygftfsttsgitigiddavipeek
kqyleeadrkllqieqayemgfltdrerydqilqlwtettekvtqavfknfeenypfnpl
yvmaqsgargnpqqirqlcglrglmqkpsgetfevpvrssfregltvleyfisshgarkg
gadtalrtadsgyltrklvdvtheivvreadcgttnyisvplfqpdevtrslrlrkradi
eaglygrvlarevevlgvrleegrylsmddvhllikaaeageiqevpvrspltcqtrygv
cqkcygydlsmarpvsigeavgivaaqsigepgtqltmrtfhtggvagaaditqglprvi
elfearrpkakaviseidgvvrieeteeklsvfvesegfskeyklpkearllvkdgdyve
agqpltrgaidphqlleakgpeaverylveeiqkvyraqgvklhdkhieivvrqmmkyve
vtdpgdsrllegqvlekwdvealnerliaegktpvawkpllmgvtksalstkswlsaasf
qntthvlteaaiagkkdeliglkenvilgrlipagtgsdfvrftqvvdqktlkaieeark
eaveakerpaarrgvkreqpgkqa

    Sequence, based on observed residues (ATOM records):
    >6p70D (D:)
kevrkvrialaspekirswsygevekpetinyrtlkperdglfderifgpikdyecacgk
ykrqrfegkvcercgvevtksivrryrmghielatpaahiwfvkdvpskigtlldlsate
leqvlyfskyivldpkgailngvpvekrqlltdeeyrelrygkqetyplppgvdalvkdg
eevvkgqelapgvvsrldgvalyrfprrvrveyvkkeraglrlplaawvekeaykpgeil
aelpepylfraeeegvvelkeleegaflvlrredepvatyflpvgmtplvvhgeivekgq
plaeakgllrmprqvraaqveaeeegetvyltlflewtepkdyrvqphmnvvvpegarve
agdkivaaidpeeeviaeaegvvhlhepasilvvkarvypfeddvevstgdrvapgdvla
dggkvksdvygrvevdlvrnvvrvvesydidarmgaeaiqqllkeldlealekelleemk
hpsrarrakarkrlevvrafldsgnrpewmileavpvlppdlrpmvqvdggrfatsdlnd
lyrrlinrnnrlkkllaqgapeiiirnekrmlqeavdalldngrrgapvtnpgsdrplrs
ltdilsgkqgrfrqnllgkrvdysgrsvivvgpqlklhqcglpkrmalelfkpfllkkme
ekgiapnvkaarrmlerqrdikdevwdaleevihgkvvllnraptlhrlgiqafqpvlve
gqsiqlhplvceafnadfdgdqmavhvplssfaqaeariqmlsahnllspasgeplakps
rdiilglyyitqvrkekkgaglefatpeealaahergevalnapikvagretsvgrlkyv
fanpdeallavahgivdlqdvvtvrymgkrletspgrilfarivaeavedekvaweliql
dvpqeknslkdlvyqaflrlgmektarlldalkyygftfsttsgitigiddavipeekkq
yleeadrkllqieqayemgfltdrerydqilqlwtettekvtqavfknfeenypfnplyv
maqsgargnpqqirqlcglrglmqkpsgetfevpvrssfregltvleyfisshgarkgga
dtalrtadsgyltrklvdvtheivvreadcgttnyisvplfqpdevtrslrlrkradiea
glygrvlarevevlgvrleegrylsmddvhllikaaeageiqevpvrspltcqtrygvcq
kcygydlsmarpvsigeavgivaaqsigepgtqltmtqglprvielfearrpkakavise
idgvvrieeteeklsvfvesegfskeyklpkearllvkdgdyveagqpltrgaidphqll
eakgpeaverylveeiqkvyraqgvklhdkhieivvrqmmkyvevtdpgdsrllegqvle
kwdvealnerliaegktpvawkpllmgvtksalstkswlsaasfqntthvlteaaiagkk
deliglkenvilgrlipagtgsdfvrftqvvdqktlkaieearkea

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6p70E (E:)
maepgidklfgmvdskyrltvvvakraqqllrhgfkntvlepeerpkmqtleglfddpna
vtwamkelltgrlvfgenlvpedrlqkemerlypveree

    Sequence, based on observed residues (ATOM records):
    >6p70E (E:)
aepgidklfgmvdskyrltvvvakraqqllrhgfkntvlepeerpkmqtleglfddpnav
twamkelltgrlvfgenlvpedrlqkemerlypv

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6p70F (F:)
mkkskrknaqaqeaqetevlvqeeaeelpefpegepdpdledpdltleddlldlpeegeg
ldleeeeedlpipkistsdpvrqylheigqvplltleeevelarkveegmeaikklseit
gldpdlirevvrakilgsarvrhipglketldpktveeidqklkslpkehkrylhiareg
eaarqhlieanlrlvvsiakkytgrglsfldliqegnqgliravekfeykrrfkfstyat
wwirqainraiadqartiripvhmvetinklsrtarqlqqelgreptyeeiaeamgpgwd
akrveetlkiaqepvsletpigdekdsfygdfipdehlpspvdaatqsllseelekalsk
lsereamvlklrkglidgrehtleevgaffgvtrerirqienkalrklkyhesrtrklrd
fld

    Sequence, based on observed residues (ATOM records):
    >6p70F (F:)
sdpvrqylheigqvplltleeevelarkveegmeaikklseitgldpdlirevvrakilg
sarvrhipglketldpktveeidqklkslpkehkrylhiaregeaarqhlieanlrlvvs
iakkytgrglsfldliqegnqgliravekfeykrrfkfstyatwwirqainraiadqart
iripvhmvetinklsrtarqlqqelgreptyeeiaeamgpgwdakrveetlkiaqepvsl
etpigdekdsfygdfipdehlpspvdaatqsllseelekalsklsereamvlklrkglid
grehtleevgaffgvtrerirqienkalrklkyhesrtrklrdfld

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    No sequence available.