PDB entry 6p6o
View 6p6o on RCSB PDB site
Description: HCV NS3/4A protease domain of genotype 1a D168E in complex with glecaprevir
Class: VIRAL PROTEIN, Hydrolase
Keywords: HCV NS3/4A protease HCV protease domain Glecaprevir, GLE Genotype 1a, VIRAL PROTEIN, Hydrolase
Deposited on
2019-06-04, released
2020-06-10
The last revision prior to the SCOPe 2.08 freeze date was dated
2020-06-10, with a file datestamp of
2020-06-05.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Non-structural protein 4A,Serine protease NS3
Species: Hepatitis C virus genotype 1a (isolate 1) [TaxId:11104]
Database cross-references and differences (RAF-indexed):
- Uniprot P26664 (10-20)
- expression tag (0-9)
- engineered mutation (11)
- engineered mutation (18-19)
- linker (21-23)
- Uniprot P26664 (24-201)
- engineered mutation (33-34)
- engineered mutation (37-38)
- engineered mutation (41)
- engineered mutation (60)
- engineered mutation (67)
- engineered mutation (72)
- engineered mutation (92)
- engineered mutation (100)
- engineered mutation (106)
- engineered mutation (188)
- engineered mutation (194)
- engineered mutation (201)
Domains in SCOPe 2.08: d6p6oa1, d6p6oa2 - Heterogens: O31, ZN, SO4, CL, HOH