PDB entry 6p6d

View 6p6d on RCSB PDB site
Description: human igg1 fc fragment, c239 insertion mutant
Class: immune system
Keywords: antibody-drug conjugate, cysteine insertion mutant, cysteine disulfide adduct, IMMUNE SYSTEM
Deposited on 2019-06-03, released 2020-04-15
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.31 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: IgG1 Fc fragment
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6MZV7
      • insertion (18)
    Domains in SCOPe 2.08: d6p6da1, d6p6da2
  • Chain 'B':
    Compound: IgG1 Fc fragment
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6MZV7
      • insertion (18)
    Domains in SCOPe 2.08: d6p6db1, d6p6db2
  • Heterogens: CYS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6p6dA (A:)
dkthtcppcpapellggpscvflfppkpkdtlmisrtpevtcvvvdvshedpevkfnwyv
dgvevhnaktkpreeqynstyrvvsvltvlhqdwlngkeykckvsnkalpapiektiska
kgqprepqvytlppsreemtknqvsltclvkgfypsdiavewesngqpennykttppvld
sdgsfflyskltvdksrwqqgnvfscsvmhealhnhytqkslslspgk

    Sequence, based on observed residues (ATOM records): (download) 
    >6p6dA (A:)
pscvflfppkpkdtlmisrtpevtcvvvdvshedpevkfnwyvdgvevhnaktkpreeqy
nstyrvvsvltvlhqdwlngkeykckvsnkalpapiektiskakgqprepqvytlppsre
emtknqvsltclvkgfypsdiavewesngqpennykttppvldsdgsfflyskltvdksr
wqqgnvfscsvmhealhnhytqkslsls

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6p6dB (B:)
dkthtcppcpapellggpscvflfppkpkdtlmisrtpevtcvvvdvshedpevkfnwyv
dgvevhnaktkpreeqynstyrvvsvltvlhqdwlngkeykckvsnkalpapiektiska
kgqprepqvytlppsreemtknqvsltclvkgfypsdiavewesngqpennykttppvld
sdgsfflyskltvdksrwqqgnvfscsvmhealhnhytqkslslspgk

    Sequence, based on observed residues (ATOM records): (download) 
    >6p6dB (B:)
pscvflfppkpkdtlmisrtpevtcvvvdvshedpevkfnwyvdgvevhnaktkpreeqy
nstyrvvsvltvlhqdwlngkeykckvsnkalpapiektiskakgqprepqvytlppsre
emtknqvsltclvkgfypsdiavewesngqpennykttppvldsdgsfflyskltvdksr
wqqgnvfscsvmhealhnhytqkslsls