PDB entry 6p54

View 6p54 on RCSB PDB site
Description: Crystal structure of transpeptidase domain of PBP2 from Neisseria gonorrhoeae acylated by ceftriaxone
Class: hydrolase/antibiotic
Keywords: Penicillin-binding protein, transpeptidase domain, Neisseria gonorrhoeae, antibiotic resistance, HYDROLASE-ANTIBIOTIC complex
Deposited on 2019-05-29, released 2019-08-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-01-01, with a file datestamp of 2019-12-27.
Experiment type: XRAY
Resolution: 1.83 Å
R-factor: N/A
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Probable peptidoglycan D,D-transpeptidase PenA
    Species: NEISSERIA GONORRHOEAE [TaxId:485]
    Gene: penA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P08149 (5-328)
      • expression tag (4)
      • conflict (51)
    Domains in SCOPe 2.08: d6p54a1, d6p54a2
  • Chain 'B':
    Compound: Probable peptidoglycan D,D-transpeptidase PenA
    Species: NEISSERIA GONORRHOEAE [TaxId:485]
    Gene: penA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P08149 (5-328)
      • expression tag (3-4)
      • conflict (51)
    Domains in SCOPe 2.08: d6p54b1, d6p54b2
  • Heterogens: NZV, 9F2, CEF, PEG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6p54A (A:)
gsggalsldqriqtlayeelnkaveyhqakagtvvvldartgeilalantpgrnravtdm
iepgsaikpfviakaldagktdlnerlntqpykigpspvrdthvypsldvrgimqkssnv
gtsklsarfgaeemydfyhelgigvrmhsgfpgetagllrnwrrwrpieqatmsfgyglq
lsllqlaraytalthdgvllplsfekqavapqgkrifkestarevrnlmvsvtepggtgt
agavdgfdvgaktgtarkfvngryadnkhvatfigfapaknprvivavtideptahgyyg
gvvagppfkkimggslnilgisptkplta

    Sequence, based on observed residues (ATOM records): (download) 
    >6p54A (A:)
alsldqriqtlayeelnkaveyhqakagtvvvldartgeilalantpgrnravtdmiepg
saikpfviakaldagktdlnerlntqpykigpspvrdthvypsldvrgimqkssnvgtsk
lsarfgaeemydfyhelgigvrmhsgfpgetagllrnwrrwrpieqatmsfgyglqlsll
qlaraytalthdgvllplsfekqavapqgkrifkestarevrnlmvsvtepggtgtagav
dgfdvgaktgtarkfvngryadnkhvatfigfapaknprvivavtideptahgyyggvva
gppfkkimggslnilgisptkplta

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6p54B (B:)
gsggalsldqriqtlayeelnkaveyhqakagtvvvldartgeilalantpgrnravtdm
iepgsaikpfviakaldagktdlnerlntqpykigpspvrdthvypsldvrgimqkssnv
gtsklsarfgaeemydfyhelgigvrmhsgfpgetagllrnwrrwrpieqatmsfgyglq
lsllqlaraytalthdgvllplsfekqavapqgkrifkestarevrnlmvsvtepggtgt
agavdgfdvgaktgtarkfvngryadnkhvatfigfapaknprvivavtideptahgyyg
gvvagppfkkimggslnilgisptkplta

    Sequence, based on observed residues (ATOM records): (download) 
    >6p54B (B:)
galsldqriqtlayeelnkaveyhqakagtvvvldartgeilalantpgrnravtdmiep
gsaikpfviakaldagktdlnerlntqpykigpspvrdthvypsldvrgimqkssnvgts
klsarfgaeemydfyhelgigvrmhsgfpgetagllrnwrrwrpieqatmsfgyglqlsl
lqlaraytalthdgvllplsfekqavapqgkrifkestarevrnlmvsvtepggtgtaga
vdgfdvgaktgtarkfvngryadnkhvatfigfapaknprvivavtideptahgyyggvv
agppfkkimggslnilgisptkplta