PDB entry 6p3t

View 6p3t on RCSB PDB site
Description: crystal structure of eis from mycobacterium tuberculosis in complex with inhibitor sgt449
Deposited on 2019-05-24, released 2019-09-04
The last revision was dated 2019-12-18, with a file datestamp of 2019-12-13.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: N-acetyltransferase Eis
    Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
    Gene: eis, Rv2416c, MTCY253.04
    Database cross-references and differences (RAF-indexed):
    • Uniprot P9WFK7 (Start-421)
      • engineered mutation (223)
  • Heterogens: NRS, GOL, PEG, SO4, DMS, NH4, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6p3tA (A:)
mgsshhhhhhssglvprgshmtvtlcspteddwpgmfllaaasftdfigpesatawrtlv
ptdgavvvrdgagpgsevvgmalymdlrltvpgevvlptaglsfvavapthrrrgllram
caelhrriadsgypvaalhaseggiygrfgygpattlheltvdrrfarfhadapggglgg
ssvrlvrptehrgefeaiyerwrqqvpggllrpqvlwdellaeakaapggdresfallhp
dgyalyrvdrtdlklarvselravtadahcalwraligldsmerisiithpqdplphllt
dtrlarttwrqdglwlrimnvpaaleargyahevgefstvlevsdggrfalkigdgrarc
tptdaaaeiemdrdvlgslylgahrastlaaanrlrtkdsqllrrldaafasdvpvqtaf
ef

    Sequence, based on observed residues (ATOM records):
    >6p3tA (A:)
vtlcspteddwpgmfllaaasftdfigpesatawrtlvptdgavvvrdgsevvgmalymd
lrltvpgevvlptaglsfvavapthrrrgllramcaelhrriadsgypvaalhaseggiy
grfgygpattlheltvdrrfarfhadapggglggssvrlvrptehrgefeaiyerwrqqv
pggllrpqvlwdellaeakaapggdresfallhpdgyalyrvdrtdlklarvselravta
dahcalwraligldsmerisiithpqdplphlltdtrlarttwrqdglwlrimnvpaale
argyahevgefstvlevsdggrfalkigdgrarctptdaaaeiemdrdvlgslylgahra
stlaaanrlrtkdsqllrrldaafasdvpvqtafef