PDB entry 6p1x

View 6p1x on RCSB PDB site
Description: structure of hiv-1 reverse transcriptase (rt) in complex with dsdna and l-ddctp
Deposited on 2019-05-20, released 2019-07-24
The last revision was dated 2020-01-01, with a file datestamp of 2019-12-27.
Experiment type: XRAY
Resolution: 2.55 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Reverse transcriptase/ribonuclease H
    Species: Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) [TaxId:11706]
    Gene: gag-pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot P04585 (0-End)
      • engineered mutation (257)
      • engineered mutation (279)
  • Chain 'B':
    Compound: p51 RT
    Species: Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) [TaxId:11706]
    Gene: gag-pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot P04585
      • engineered mutation (291)
  • Chain 'P':
    Compound: DNA Primer 20-mer
    Species: synthetic construct, synthetic [TaxId:32630]
  • Chain 'T':
    Compound: DNA template 27-mer
    Species: synthetic construct, synthetic [TaxId:32630]
  • Heterogens: NQ4, MG, SO4, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6p1xA (A:)
pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpv
faikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpl
dedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdivi
yqymddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwt
vqpivlpekdswtvndicklvgklnwasqiypgikvrqlskllrgtkalteviplteeae
lelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrga
htndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntp
plvklwyqlekepivgaetfyvdgaanretklgkagyvtnrgrqkvvtltdttnqktelq
aiylalqdsglevnivtdsqyalgiiqaqpdqseselvnqiieqlikkekvylawvpahk
giggneqvdklvsagirkvl

    Sequence, based on observed residues (ATOM records):
    >6p1xA (A:)
pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpv
faikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpl
dedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdivi
yqymddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwt
vqpivlpekdswtvndicklvgklnwasqiypgikvrqlskllrgtkalteviplteeae
lelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrga
htndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntp
plvklwyqlekepivgaetfyvdgaanretklgkagyvtnrgrqkvvtltdttnqktelq
aiylalqdsglevnivtdsqyalgiiqaqpdqseselvnqiieqlikkekvylawvpahk
giggneqvdklvsagir

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6p1xB (B:)
mgsshhhhhhsspispietvpvklkpgmdgpkvkqwplteekikalveictemekegkis
kigpenpyntpvfaikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtv
ldvgdayfsvpldedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkil
epfrkqnpdiviyqymddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppfl
wmgyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiypgikvrqlskllrgtka
lteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfkn
lktgkyarmrgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqa
twipewefvntpplvklwyqlekepivgaetf

    Sequence, based on observed residues (ATOM records):
    >6p1xB (B:)
etvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikk
kdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpldedfr
kytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqymd
dlyvgsdleigqhrtkieelrqhllrmgyelhpdkwtvqpivlpekdswtvndiqklvgk
lnwasqiypgikvrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpsk
dliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkittesiviw
gktpkfklpiqketwetwwteywqatwipewefvntpplvklwyql

  • Chain 'P':
    No sequence available.

  • Chain 'T':
    No sequence available.