PDB entry 6p1w

View 6p1w on RCSB PDB site
Description: pre-catalytic ternary complex of human dna polymerase mu with 1-nt gapped substrate containing undamaged template dg and bound incoming cmpcpp
Deposited on 2019-05-20, released 2019-09-04
The last revision was dated 2019-12-18, with a file datestamp of 2019-12-13.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: N/A
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA-directed DNA/RNA polymerase mu
    Species: Homo sapiens [TaxId:9606]
    Gene: POLM, polmu
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NP87 (Start-353)
      • linker (269)
  • Chain 'D':
    Compound: DNA (5'-d(p*gp*cp*cp*g)-3')
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
  • Chain 'P':
    Compound: DNA (5'-d(*cp*gp*tp*a)-3')
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
  • Chain 'T':
    Compound: DNA (5'-d(*cp*gp*gp*cp*gp*tp*ap*cp*g)-3')
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
  • Heterogens: 2TM, MG, NA, CL, EPE, EDO, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6p1wA (A:)
gsaaaspawmpayacqrptplthhntglsealeilaeaagfegsegrlltfcraasvlka
lpspvttlsqlqglphfgehssrvvqellehgvceevervrrseryqtmklftqifgvgv
ktadrwyreglrtlddlreqpqkltqqqkaglqhhqdlstpvlrsdvdalqqvveeavgq
alpgatvtltggfrrgklqghdvdflithpkegqeagllprvmcrlqdqglilyhqhqhs
ccesptrlaqqshmdafersfcifrlpqpgswkavrvdlvvapvsqfpfallgwtgsklf
qrelrrfsrkekglwlnshglfdpeqktffqaaseedifrhlgleylppeqrna

    Sequence, based on observed residues (ATOM records):
    >6p1wA (A:)
mpayacqrptplthhntglsealeilaeaagfegsegrlltfcraasvlkalpspvttls
qlqglphfgehssrvvqellehgvceevervrrseryqtmklftqifgvgvktadrwyre
glrtlddlreqpqkltqqqkaglqhhqdlstpvlrsdvdalqqvveeavgqalpgatvtl
tggfrrgklqghdvdflithpkegqeagllprvmcrlqdqglilyhqhqafersfcifrl
pqpgswkavrvdlvvapvsqfpfallgwtgsklfqrelrrfsrkekglwlnshglfdpeq
ktffqaaseedifrhlgleylppeqrna

  • Chain 'D':
    No sequence available.

  • Chain 'P':
    No sequence available.

  • Chain 'T':
    No sequence available.