PDB entry 6p0d

View 6p0d on RCSB PDB site
Description: human dna ligase 1 (e346a/e592a) bound to an adenylated, hydroxyl terminated dna nick
Deposited on 2019-05-16, released 2019-12-11
The last revision was dated 2019-12-11, with a file datestamp of 2019-12-06.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: N/A
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA ligase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: LIG1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P18858 (2-End)
      • expression tag (1)
      • engineered mutation (86)
      • engineered mutation (332)
  • Chain 'B':
    Compound: DNA (5'-d(*gp*cp*tp*gp*ap*tp*gp*cp*gp*tp*c)-3')
    Species: synthetic construct, synthetic [TaxId:32630]
  • Chain 'C':
    Compound: DNA (5'-d(p*gp*tp*cp*gp*gp*ap*c)-3')
    Species: synthetic construct, synthetic [TaxId:32630]
  • Chain 'D':
    Compound: DNA (5'-d(*gp*tp*cp*cp*gp*ap*cp*gp*ap*cp*gp*cp*ap*tp*cp*ap*gp*c)-3')
    Species: synthetic construct, synthetic [TaxId:32630]
  • Heterogens: PEG, AMP, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6p0dA (A:)
sndpsgynpaknnyhpvedacwkpgqkvpylavartfekieevsarlrmvetlsnllrsv
valsppdllpvlylslnhlgppqqglalgvgdgvllkavaqatgrqlesvraeaaekgdv
glvaensrstqrlmlppppltasgvfskfrdiarltgsastakkidiikglfvacrhsea
rfiarslsgrlrlglaeqsvlaalsqavsltppgqefppamvdagkgktaearktwleeq
gmilkqtfcevpdldriipvllehglerlpehcklspgiplkpmlahptrgisevlkrfe
eaaftceykydgqraqihaleggevkifsrnqadntgkypdiisripkiklpsvtsfild
teavawdrekkqiqpfqvlttrkrkevdaseiqvqvclyafdliylngeslvreplsrrr
qllrenfvetegefvfatsldtkdieqiaefleqsvkdsceglmvktldvdatyeiakrs
hnwlklkkdyldgvgdtldlvvigaylgrgkragryggfllasydedseelqaicklgtg
fsdeeleehhqslkalvlpsprpyvridgavipdhwldpsavwevkcadlslspiypaar
glvdsdkgislrfprfirvredkqpeqattsaqvaclyrkqsqiq

    Sequence, based on observed residues (ATOM records):
    >6p0dA (A:)
ndpsgynpaknnyhpvedacwkpgqkvpylavartfekieevsarlrmvetlsnllrsvv
alsppdllpvlylslnhlgppqqglalgvgdgvllkavaqatgrqlesvraeaaekgdvg
lvaensrstqrlmlppppltasgvfskfrdiarltgsastakkidiikglfvacrhsear
fiarslsgrlrlglaeqsvlaalsqavsltppgqefppamvdagkgktaearktwleeqg
milkqtfcevpdldriipvllehglerlpehcklspgiplkpmlahptrgisevlkrfee
aaftceykydgqraqihaleggevkifsrnqadntgkypdiisripkiklpsvtsfildt
eavawdrekkqiqpfqvlttrkrkevdaseiqvqvclyafdliylngeslvreplsrrrq
llrenfvetegefvfatsldtkdieqiaefleqsvkdsceglmvktldvdatyeiakrsh
nwlklkkdyldgvgdtldlvvigaylgrgkragryggfllasydedseelqaicklgtgf
sdeeleehhqslkalvlpsprpyvridgavipdhwldpsavwevkcadlslspiypaarg
lvdsdkgislrfprfirvredkqpeqattsaqvaclyrkqs

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.