PDB entry 6oye

View 6oye on RCSB PDB site
Description: Crystal structure of Y99F mutant of human macrophage migration inhibitory factor
Class: isomerase
Keywords: Isomerase, trimeric, mutation
Deposited on 2019-05-14, released 2020-04-29
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-22, with a file datestamp of 2020-07-17.
Experiment type: XRAY
Resolution: 1.53 Å
R-factor: N/A
AEROSPACI score: 0.57 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: macrophage migration inhibitory factor
  Species: Homo sapiens [TaxId:9606]
  Gene: MIF, GLIF, MMIF
  Database cross-references and differences (RAF-indexed):
  • Uniprot P14174 (0-113)
    • engineered mutation (98)
  Domains in SCOPe 2.08: d6oyea_
• Chain 'B':
  Compound: macrophage migration inhibitory factor
  Species: Homo sapiens [TaxId:9606]
  Gene: MIF, GLIF, MMIF
  Database cross-references and differences (RAF-indexed):
  • Uniprot P14174 (0-113)
    • engineered mutation (98)
  Domains in SCOPe 2.08: d6oyeb_
• Chain 'C':
  Compound: macrophage migration inhibitory factor
  Species: Homo sapiens [TaxId:9606]
  Gene: MIF, GLIF, MMIF
  Database cross-references and differences (RAF-indexed):
  • Uniprot P14174 (0-113)
    • engineered mutation (98)
  Domains in SCOPe 2.08: d6oyec_
• Heterogens: GOL, SO4, IPA, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >6oyeA (A:)
  pmfivntnvprasvpdgflseltqqlaqatgkppqyiavhvvpdqlmafggssepcalcs
  lhsigkiggaqnrsyskllcgllaerlrispdrvyinyfdmnaanvgwnnstfa
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >6oyeB (B:)
  pmfivntnvprasvpdgflseltqqlaqatgkppqyiavhvvpdqlmafggssepcalcs
  lhsigkiggaqnrsyskllcgllaerlrispdrvyinyfdmnaanvgwnnstfa
  

  
  
• Chain 'C':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >6oyeC (C:)
  pmfivntnvprasvpdgflseltqqlaqatgkppqyiavhvvpdqlmafggssepcalcs
  lhsigkiggaqnrsyskllcgllaerlrispdrvyinyfdmnaanvgwnnstfa