PDB entry 6ox4

View 6ox4 on RCSB PDB site
Description: a setd3 mutant (n255a) in complex with an actin peptide
Deposited on 2019-05-13, released 2019-08-21
The last revision was dated 2020-01-01, with a file datestamp of 2019-12-27.
Experiment type: XRAY
Resolution: 2.29 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Actin-histidine N-methyltransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: SETD3, C14orf154
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q86TU7
      • engineered mutation (260)
  • Chain 'B':
    Compound: Actin-histidine N-methyltransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: SETD3, C14orf154
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q86TU7
      • engineered mutation (260)
  • Chain 'Y':
    Compound: Actin Peptide
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'Z':
    Compound: Actin Peptide
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: EDO, SAH, GOL, ACT, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6ox4A (A:)
gplgsmgkksrvktqksgtgatatvspkeilnltsellqkcsspapgpgkeweeyvqirt
lvekirkkqkglsvtfdgkredyfpdlmkwasengasvegfemvnfkeegfglratrdik
aeelflwvprkllmtvesaknsvlgplysqdrilqamgnialafhllceraspnsfwqpy
iqtlpseydtplyfeedevrylqstqaihdvfsqykntarqyayfykviqthphanklpl
kdsftyedyrwavssvmtrqaqiptedgsrvtlaliplwdmcnhtnglittgynleddrc
ecvalqdfrageqiyifygtrsnaefvihsgfffdnnshdrvkiklgvsksdrlyamkae
vlaragiptssvfalhfteppisaqllaflrvfcmteeelkehllgdsaidriftlgnse
fpvswdnevklwtfledraslllktykttieedksvlknhdlsvrakmaiklrlgekeil
ekavksaavnreyyrqqmeekaplpkyeesnlgllessvgdsrlplvlrnleeeagvqda
lnireaiskakatenglvngensipngtrseneslnqeskravedakgsssdstagvke

    Sequence, based on observed residues (ATOM records):
    >6ox4A (A:)
vspkeilnltsellqkcsspapgpgkeweeyvqirtlvekirkkqkglsvtfdgkredyf
pdlmkwasengasvegfemvnfkeegfglratrdikaeelflwvprkllmtvesaknsvl
gplysqdrilqamgnialafhllceraspnsfwqpyiqtlpseydtplyfeedevrylqs
tqaihdvfsqykntarqyayfykviqthphanklplkdsftyedyrwavssvmtrqaqip
tedgsrvtlaliplwdmcnhtnglittgynleddrcecvalqdfrageqiyifygtrsna
efvihsgfffdnnshdrvkiklgvsksdrlyamkaevlaragiptssvfalhfteppisa
qllaflrvfcmteeelkehllgdsaidriftlgnsefpvswdnevklwtfledraslllk
tykttieedksvlknhdlsvrakmaiklrlgekeilekavksaavnreyyrqqmeekapl
pky

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6ox4B (B:)
gplgsmgkksrvktqksgtgatatvspkeilnltsellqkcsspapgpgkeweeyvqirt
lvekirkkqkglsvtfdgkredyfpdlmkwasengasvegfemvnfkeegfglratrdik
aeelflwvprkllmtvesaknsvlgplysqdrilqamgnialafhllceraspnsfwqpy
iqtlpseydtplyfeedevrylqstqaihdvfsqykntarqyayfykviqthphanklpl
kdsftyedyrwavssvmtrqaqiptedgsrvtlaliplwdmcnhtnglittgynleddrc
ecvalqdfrageqiyifygtrsnaefvihsgfffdnnshdrvkiklgvsksdrlyamkae
vlaragiptssvfalhfteppisaqllaflrvfcmteeelkehllgdsaidriftlgnse
fpvswdnevklwtfledraslllktykttieedksvlknhdlsvrakmaiklrlgekeil
ekavksaavnreyyrqqmeekaplpkyeesnlgllessvgdsrlplvlrnleeeagvqda
lnireaiskakatenglvngensipngtrseneslnqeskravedakgsssdstagvke

    Sequence, based on observed residues (ATOM records):
    >6ox4B (B:)
vspkeilnltsellqkcsspapgpgkeweeyvqirtlvekirkkqkglsvtfdgkredyf
pdlmkwasengasvegfemvnfkeegfglratrdikaeelflwvprkllmtvesaknsvl
gplysqdrilqamgnialafhllceraspnsfwqpyiqtlpseydtplyfeedevrylqs
tqaihdvfsqykntarqyayfykviqthphanklplkdsftyedyrwavssvmtrqaqip
tedgsrvtlaliplwdmcnhtnglittgynleddrcecvalqdfrageqiyifygtrsna
efvihsgfffdnnshdrvkiklgvsksdrlyamkaevlaragiptssvfalhfteppisa
qllaflrvfcmteeelkehllgdsaidriftlgnsefpvswdnevklwtfledraslllk
tykttieedksvlknhdlsvrakmaiklrlgekeilekavksaavnreyyrqqmeekapl
pky

  • Chain 'Y':
    Sequence; same for both SEQRES and ATOM records:
    >6ox4Y (Y:)
tlkypiehgivtnwd

  • Chain 'Z':
    Sequence; same for both SEQRES and ATOM records:
    >6ox4Z (Z:)
tlkypiehgivtnwd