PDB entry 6owo

View 6owo on RCSB PDB site
Description: cryo-em structure of phosphorylated ap-2 core bound to necap
Deposited on 2019-05-10, released 2019-09-11
The last revision was dated 2020-01-08, with a file datestamp of 2020-01-03.
Experiment type: EM
Resolution: 3.2 Å
R-factor: N/A
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ap-2 complex subunit alpha-2
    Species: Mus musculus [TaxId:10090]
    Gene: Ap2a2, Adtab
    Database cross-references and differences (RAF-indexed):
    • PDB 6OWO
  • Chain 'B':
    Compound: ap-2 complex subunit beta
    Species: Mus musculus [TaxId:10090]
    Gene: AP2B1, CLAPB1
    Database cross-references and differences (RAF-indexed):
  • Chain 'M':
    Compound: ap-2 complex subunit mu
    Species: Mus musculus [TaxId:10090]
    Gene: Ap2m1, Clapm1
    Database cross-references and differences (RAF-indexed):
  • Chain 'N':
    Compound: Adaptin ear-binding coat-associated protein 2
    Species: Mus musculus [TaxId:10090]
    Gene: Necap2
    Database cross-references and differences (RAF-indexed):
  • Chain 'S':
    Compound: ap-2 complex subunit sigma
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Ap2s1, Ap17, Claps2
    Database cross-references and differences (RAF-indexed):

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6owoA (A:)
mpavskgegmrglavfisdirnckskeaeikrinkelanirskfkgdkaldgyskkkyvc
kllfifllghdidfghmeavnllssnrytekqigylfisvlvnsnselirlinnaikndl
asrnptfmglalhcianvgsremaeafageipkilvagdtmdsvkqsaalcllrlyrtsp
dlvpmgdwtsrvvhllndqhlgvvtaatslittlaqknpeefktsvslavsrlsrivtsa
stdlqdytyyfvpapwlsvkllrllqcypppedpavrgrltecletilnkaqeppkskkv
qhsnaknavlfeaisliihhdsepnllvracnqlgqflqhretnlrylalesmctlasse
fsheavkthietvinalkterdvsvrqravdllyamcdrsnaqqivaemlsyletadysi
reeivlkvailaekyavdytwyvdtilnliriagdyvseevwyrviqivinrddvqgyaa
ktvfealqapachenlvkvggyilgefgnliagdprsspliqfnllhskfhlcsvptral
llstyikfvnlfpevkatiqdvlrsdsqlknadvelqqraveylrlstvastdilatvle
emppfperessilaklkkkkg

    Sequence, based on observed residues (ATOM records):
    >6owoA (A:)
rglavfisdirnckskeaeikrinkelanirskfldgyskkkyvckllfifllghdidfg
hmeavnllssnrytekqigylfisvlvnsnselirlinnaikndlasrnptfmglalhci
anvgsremaeafageipkilvagdtmdsvkqsaalcllrlyrtspdlvpmgdwtsrvvhl
lndqhlgvvtaatslittlaqknpeefktsvslavsrlsrivtlqdytyyfvpapwlsvk
llrllqcypppedpavrgrltecletilnkaqeppkskkvqhsnaknavlfeaisliihh
dsepnllvracnqlgqflqhretnlrylalesmctlassefsheavkthietvinalkte
rdvsvrqravdllyamcdrsnaqqivaemlsyletadysireeivlkvailaekyavdyt
wyvdtilnliriagdyvseevwyrviqivinrddvqgyaaktvfealqapachenlvkvg
gyilgefgnliagdprsspliqfnllhskfhlcsvptralllstyikfvnlfpevkatiq
dvlrsdsqlknadvelqqraveylrlstv

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6owoB (B:)
mtdskyfttnkkgeifelkaelnnekkekrkeavkkviaamtvgkdvsslfpdvvncmqt
dnlelkklvylylmnyaksqpdmaimavnsfvkdcedpnpliralavrtmgcirvdkite
ylceplrkclkdedpyvrktaavcvaklhdinaqmvedqgfldslrdliadsnpmvvana
vaalseiseshpnsnlldlnpqninklltalnectewgqifildclsnynpkddreaqsi
cervtprlshansavvlsavkvlmkflellpkdsdyynmllkklapplvtllsgepevqy
valrninlivqkrpeilkqeikvffvkyndpiyvklekldimirlasqaniaqvlaelke
yatevdvdfvrkavraigrcaikveqsaercvstlldliqtkvnyvvqeaivvirdifrk
ypnkyesiiatlcenldsldepdaraamiwivgeyaeridnadellesflegfhdestqv
qltlltaivklflkkpsetqelvqqvlslatqdsdnpdlrdrgyiywrllstdpvtakev
vlsekpliseetdlieptlldelichigslasvyhkppnafvegshgihrk

    Sequence, based on observed residues (ATOM records):
    >6owoB (B:)
kyfttnkkgeifelkaelnnekkekrkeavkkviaamtvgkdvsslfpdvvncmqtdnle
lkklvylylmnyaksqpdmaimavnsfvkdcedpnpliralavrtmgcirvdkiteylce
plrkclkdedpyvrktaavcvaklhdivedqgfldslrdliadsnpmvvanavaalseis
eshlldlnpqninklltalnectewgqifildclsnynpkddreaqsicervtprlshan
savvlsavkvlmkfledyynmllkklapplvtllsgepevqyvalrninlivqkrpeilk
qeikvffvkyndpiyvklekldimirlasqaniaqvlaelkeyatevdvdfvrkavraig
rcaikveqsaercvstlldliqtkvnyvvqeaivvirdifrkypnkyesiiatlcenlds
ldepdaraamiwivgeyaeridnadellesflegfhdestqvqltlltaivklflkkpse
tqelvqqvlslatqdsdnpdlrdrgyiywrllstdpvtakevvlsekplidlieptllde
lichigslasvyhkppnaf

  • Chain 'M':
    Sequence, based on SEQRES records:
    >6owoM (M:)
migglfiynhkgevlisrvyrddigrnavdafrvnviharqqvrspvtniartsffhvkr
sniwlaavtkqnvnaamvfeflykmcdvmaayfgkiseeniknnfvliyelldeildfgy
pqnsetgalktfitqqgiksqhqtkeeqsqitsqvtgqigwrregikyrrnelfldvles
vnllmspqgqvlsahvsgrvvmksylsgmpeckfgmndkiviekqgkgtadetsksgkqs
iaiddctfhqcvrlskfdsersisfippdgefelmryrttkdiilpfrviplvrevgrtk
levkvviksnfkpsllaqkievriptplntsgvqvicmkgkakykasenaivwkikrmag
mkesqisaeiellptndkkkwarppismnfevpfapsglkvrylkvfepklnysdhdvik
wvryigrsgiyetrc

    Sequence, based on observed residues (ATOM records):
    >6owoM (M:)
igglfiynhkgevlisrvyrddigrnavdafrvnviharqqvrspvtniartsffhvkrs
niwlaavtkqnvnaamvfeflykmcdvmaayfgkiseeniknnfvliyelldeildfgyp
qnsetgalktfitqqgiksqvtgqigwrregikyrrnelfldvlesvnllmspqgqvlsa
hvsgrvvmksylsgmpeckfgmndkiviiaiddctfhqcvrlsersisfippdgefelmr
yrttkdiilpfrviplvrevgrtklevkvviksnfkpsllaqkievriptplntsgvqvi
cmkgkakykasenaivwkikrmagmkesqisaeiellpkkwarppismnfevpfapsglk
vrylkvfepklnysdhdvikwvryigrsgiyetrc

  • Chain 'N':
    Sequence, based on SEQRES records:
    >6owoN (N:)
meeseyesvlcvkpevhvyrippratnrgyrasewqldqpswsgrlritakgkvayikle
drtsgelfaqapvdqfpgtavesvtdssryfviriedgngrrafiglgfgdrgdafdfnv
alqdhfkwvkqqcefakqaqnpdegpkldlgfkdgqtikinianmrkkegaagtprarpt
sagglsllppppggksstvippsgeqlsvggslvqpavvsgsggatelwpqskpaaaata
diwgdftkstgspssqsqpgtgwvqf

    Sequence, based on observed residues (ATOM records):
    >6owoN (N:)
esvlcvkpevhvyrippgyrasewqldqpswsgrlritakgkvayikledrtsgelfaqa
pvdqfpgtavesvtdssryfvirierafiglgfgdrgdafdfnvalqdhfkwvkqqcefa
kq

  • Chain 'S':
    Sequence, based on SEQRES records:
    >6owoS (S:)
mirfiliqnragktrlakwymqfdddekqklieevhavvtvrdakhtnfvefrnfkiiyr
ryaglyfcicvdvndnnlayleaihnfvevlneyfhnvceldlvfnfykvytvvdemfla
geiretsqtkvlkqllmlqsle

    Sequence, based on observed residues (ATOM records):
    >6owoS (S:)
mirfiliqnragktrlakwymqfdddekqklieevhavvtvrdakhtnfvefrnfkiiyr
ryaglyfcicvdvndnnlayleaihnfvevlneyfhnvceldlvfnfykvytvvdemfla
geiretsqtkvlkqllmlqsl