PDB entry 6owi

View 6owi on RCSB PDB site
Description: Crystal structure of MYST acetyltransferase domain in complex with inhibitor 85
Class: transferase/transerase inhibitor
Keywords: Inhibitor, Complex, MYST, TRANSFERASE, TRANSFERASE-TRANSERASE INHIBITOR complex
Deposited on 2019-05-09, released 2020-04-01
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-04-01, with a file datestamp of 2020-03-27.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: N/A
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Histone acetyltransferase KAT8
    Species: Homo sapiens [TaxId:9606]
    Gene: KAT8, MOF, MYST1, PP7073
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9H7Z6
      • conflict (73)
      • engineered mutation (139)
      • engineered mutation (142-143)
      • engineered mutation (154)
      • conflict (196)
    Domains in SCOPe 2.07: d6owia_
  • Heterogens: NB7, ZN, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6owiA (A:)
vkyvdkihignyeidawyfspfpedygkqpklwlceyclkymkyeksyrfhlgqcqwrqp
pgkeiyrksnisvhevdgkdhkiycqnlcllaklfldhktlyfdvepfvfyiltevdrqg
ahivgyfskekespdgnnvscimilppyqrrgygrfliafsyelsklestvgspekplsd
lgklsyrsywswvllenlrdfrgtlsikdlsqmtsitqndiistlqslnmvkywkgqhvi
cvtpklveehlksaqykkppitvdsvclkwapp

    Sequence, based on observed residues (ATOM records): (download) 
    >6owiA (A:)
kyvdkihignyeidawyfspfpedygkqpklwlceyclkymkyeksyrfhlgqcqwrqpp
gkeiyrksnisvhevdgkdhkiycqnlcllaklfldhktlyfdvepfvfyiltevdrqga
hivgyfskekespdgnnvscimilppyqrrgygrfliafsyelsklestvgspekplsdl
gklsyrsywswvllenlrdftlsikdlsqmtsitqndiistlqslnmvkywkgqhvicvt
pklveehlksaqykkppitvdsvclkwap