PDB entry 6ow0

View 6ow0 on RCSB PDB site
Description: Crystal structure of mithramycin 3-side chain keto-reductase MtmW in complex with NAD+ and PEG
Class: oxidoreductase
Keywords: Natural product, Biosynthesis, Aureolic acid, Reductase, OXIDOREDUCTASE
Deposited on 2019-05-08, released 2019-11-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-01-15, with a file datestamp of 2020-01-10.
Experiment type: XRAY
Resolution: 2.67 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: MtmW
    Species: Streptomyces argillaceus [TaxId:41951]
    Database cross-references and differences (RAF-indexed):
    • PDB 6OW0 (0-End)
    Domains in SCOPe 2.08: d6ow0a_
  • Chain 'B':
    Compound: MtmW
    Species: Streptomyces argillaceus [TaxId:41951]
    Database cross-references and differences (RAF-indexed):
    • PDB 6OW0 (0-End)
    Domains in SCOPe 2.08: d6ow0b_
  • Heterogens: PEG, NAP, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6ow0A (A:)
mefrslgrsglsvseivygnllypqddtpdevvlssiraaldagvttfdtadvygmfrse
sllgralagtpreelvlctkvgmptgfgpngrglsrkhvmesvdgslrrlrvdhidvyta
hrydpatpleelmwtfsdlvragkilyvgmsewpveriaeaagigarlgvpvichmprys
mlwrapeaevipacrdlgigqicyftleqgvltgkyapgapppagsratapkggraplmr
rwldddkvlgrverlrplaeeaglttaqlalawvlqnpgvsgavigsfnaeqvlanaesa
gvrletdllvridevlgdsvvhdeelehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6ow0A (A:)
mefrslgrsglsvseivygnllypqddtpdevvlssiraaldagvttfdtadvygmfrse
sllgralagtpreelvlctkvgmptgfgpngrglsrkhvmesvdgslrrlrvdhidvyta
hrydpatpleelmwtfsdlvragkilyvgmsewpveriaeaagigarlgvpvichmprys
mlwrapeaevipacrdlgigqicyftleqgvltgkyapgapppagsratapkggraplmr
rwldddkvlgrverlrplaeeaglttaqlalawvlqnpgvsgavigsfnaeqvlanaesa
gvrletdllvridevlgdsvvhd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6ow0B (B:)
mefrslgrsglsvseivygnllypqddtpdevvlssiraaldagvttfdtadvygmfrse
sllgralagtpreelvlctkvgmptgfgpngrglsrkhvmesvdgslrrlrvdhidvyta
hrydpatpleelmwtfsdlvragkilyvgmsewpveriaeaagigarlgvpvichmprys
mlwrapeaevipacrdlgigqicyftleqgvltgkyapgapppagsratapkggraplmr
rwldddkvlgrverlrplaeeaglttaqlalawvlqnpgvsgavigsfnaeqvlanaesa
gvrletdllvridevlgdsvvhdeelehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6ow0B (B:)
mefrslgrsglsvseivygnllytpdevvlssiraaldagvttfdtadvygmfrsesllg
ralagtpreelvlctkvgmptgfgpngrglsrkhvmesvdgslrrlrvdhidvytahryd
patpleelmwtfsdlvragkilyvgmsewpveriaeaagigarlgvpvichmprysmlwr
apeaevipacrdlgigqicyftleqgvltgkaplmrrwldddkvlgrverlrplaeeagl
ttaqlalawvlqnpgvsgavigsfnaeqvlanaesagvrletdllvridevlgdsvvhde
e