PDB entry 6os7

View 6os7 on RCSB PDB site
Description: E. coli fumarase mutant - R126A
Class: lyase
Keywords: fumarase, metabolism, Krebs Cycle, LYASE
Deposited on 2019-05-01, released 2020-05-06
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-05-06, with a file datestamp of 2020-05-01.
Experiment type: XRAY
Resolution: 1.36 Å
R-factor: N/A
AEROSPACI score: 0.55 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: fumarate hydratase class II
    Species: Escherichia coli (strain K12) [TaxId:83333]
    Gene: fumC, b1611, JW1603
    Database cross-references and differences (RAF-indexed):
    • Uniprot P05042 (0-End)
      • engineered mutation (125)
    Domains in SCOPe 2.08: d6os7a_
  • Chain 'B':
    Compound: fumarate hydratase class II
    Species: Escherichia coli (strain K12) [TaxId:83333]
    Gene: fumC, b1611, JW1603
    Database cross-references and differences (RAF-indexed):
    • Uniprot P05042
      • engineered mutation (125)
    Domains in SCOPe 2.08: d6os7b_
  • Heterogens: FLC, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6os7A (A:)
mntvrsekdsmgaidvpadklwgaqtqrslehfristekmptslihalaltkraaakvne
dlgllseekasairqaadevlagqhddefplaiwqtgsgtqsnmnmnevlanrasellgg
vrgmeakvhpnddvnksqssndvfptamhvaallalrkqlipqlktltqtlneksrafad
ivkigrthlqdatpltlgqeisgwvamlehnlkhieyslphvaelalggtavgtglnthp
eyarrvadelavitcapfvtapnkfealatcdalvqahgalkglaaslmkiandvrwlas
gprcgigeisipenepgssimpgkvnptqcealtmlccqvmgndvainmggasgnfelnv
frpmvihnflqsvrlladgmesfnkhcavgiepnrerinqllneslmlvtalnthigydk
aaeiakkahkegltlkaaalalgylseaefdswvrpeqmvgsmkagrhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6os7A (A:)
mntvrsekdsmgaidvpadklwgaqtqrslehfristekmptslihalaltkraaakvne
dlgllseekasairqaadevlagqhddefplaiwqtgsgtqsnmnmnevlanrasellgg
vrgmeakvhpnddvnksqssndvfptamhvaallalrkqlipqlktltqtlneksrafad
ivkigrthlqdatpltlgqeisgwvamlehnlkhieyslphvaelalggtavgtglnthp
eyarrvadelavitcapfvtapnkfealatcdalvqahgalkglaaslmkiandvrwlas
gprcgigeisipenepkvnptqcealtmlccqvmgndvainmggasgnfelnvfrpmvih
nflqsvrlladgmesfnkhcavgiepnrerinqllneslmlvtalnthigydkaaeiakk
ahkegltlkaaalalgylseaefdswvrpeqmvg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6os7B (B:)
mntvrsekdsmgaidvpadklwgaqtqrslehfristekmptslihalaltkraaakvne
dlgllseekasairqaadevlagqhddefplaiwqtgsgtqsnmnmnevlanrasellgg
vrgmeakvhpnddvnksqssndvfptamhvaallalrkqlipqlktltqtlneksrafad
ivkigrthlqdatpltlgqeisgwvamlehnlkhieyslphvaelalggtavgtglnthp
eyarrvadelavitcapfvtapnkfealatcdalvqahgalkglaaslmkiandvrwlas
gprcgigeisipenepgssimpgkvnptqcealtmlccqvmgndvainmggasgnfelnv
frpmvihnflqsvrlladgmesfnkhcavgiepnrerinqllneslmlvtalnthigydk
aaeiakkahkegltlkaaalalgylseaefdswvrpeqmvgsmkagrhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6os7B (B:)
tvrsekdsmgaidvpadklwgaqtqrslehfristekmptslihalaltkraaakvnedl
gllseekasairqaadevlagqhddefplaiwqtgsgtqsnmnmnevlanrasellggvr
gmeakvhpnddvnksqssndvfptamhvaallalrkqlipqlktltqtlneksrafadiv
kigrthlqdatpltlgqeisgwvamlehnlkhieyslphvaelalggtavgtglnthpey
arrvadelavitcapfvtapnkfealatcdalvqahgalkglaaslmkiandvrwlasgp
rcgigeisipenepgssimpgkvnptqcealtmlccqvmgndvainmggasgnfelnvfr
pmvihnflqsvrlladgmesfnkhcavgiepnrerinqllneslmlvtalnthkahkegl
tlkaaaaefdswvrpeqmvg