PDB entry 6ooa

View 6ooa on RCSB PDB site
Description: Human CYP3A4 bound to a drug substrate
Class: oxidoreductase
Keywords: substrate, complex, OXIDOREDUCTASE
Deposited on 2019-04-22, released 2019-09-11
The last revision prior to the SCOPe 2.07 freeze date was dated 2019-09-11, with a file datestamp of 2019-09-06.
Experiment type: XRAY
Resolution: 2.52 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cytochrome p450 3a4
    Species: Homo sapiens [TaxId:9606]
    Gene: CYP3A4, CYP3A3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6ooaa_
  • Heterogens: MWY, HEM, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6ooaA (A:)
maylygthshglfkklgipgptplpflgnilsyhkgfcmfdmechkkygkvwgfydgqqp
vlaitdpdmiktvlvkecysvftnrrpfgpvgfmksaisiaedeewkrlrsllsptftsg
klkemvpiiaqygdvlvrnlrreaetgkpvtlkdvfgaysmdvitstsfgvnidslnnpq
dpfventkkllrfdfldpfflsitvfpflipilevlnicvfprevtnflrksvkrmkesr
ledtqkhrvdflqlmidsqnsketeshkalsdlelvaqsiififagyettssvlsfimye
lathpdvqqklqeeidavlpnkapptydtvlqmeyldmvvnetlrlfpiamrlervckkd
veingmfipkgvvvmipsyalhrdpkywtepekflperfskknkdnidpyiytpfgsgpr
ncigmrfalmnmklalirvlqnfsfkpcketqiplklslggllqpekpvvlkvesrdgtv
sgahhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6ooaA (A:)
hshglfkklgipgptplpflgnilsyhkgfcmfdmechkkygkvwgfydgqqpvlaitdp
dmiktvlvkecysvftnrrpfgpvgfmksaisiaedeewkrlrsllsptftsgklkemvp
iiaqygdvlvrnlrreaetgkpvtlkdvfgaysmdvitstsfgvnidslnnpqdpfvent
kklpfflsitvfpflipilevlnicvfprevtnflrksvkrmkesrlrvdflqlmidsqn
sshkalsdlelvaqsiififagyettssvlsfimyelathpdvqqklqeeidavlpnkap
ptydtvlqmeyldmvvnetlrlfpiamrlervckkdveingmfipkgvvvmipsyalhrd
pkywtepekflperfskknkdnidpyiytpfgsgprncigmrfalmnmklalirvlqnfs
fkpcketqiplklslggllqpekpvvlkvesr