PDB entry 6ohs

View 6ohs on RCSB PDB site
Description: structure of compound 3 (ml299) bound human phospholipase d2 catalytic domain
Deposited on 2019-04-06, released 2020-02-19
The last revision was dated 2020-04-01, with a file datestamp of 2020-03-27.
Experiment type: XRAY
Resolution: 3.2 Å
R-factor: N/A
AEROSPACI score: 0.12 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Phospholipase D2
    Species: Homo sapiens [TaxId:9606]
    Gene: PLD2
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Phospholipase D2
    Species: Homo sapiens [TaxId:9606]
    Gene: PLD2
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Phospholipase D2
    Species: Homo sapiens [TaxId:9606]
    Gene: PLD2
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Phospholipase D2
    Species: Homo sapiens [TaxId:9606]
    Gene: PLD2
    Database cross-references and differences (RAF-indexed):
  • Heterogens: MJY

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6ohsA (A:)
ssyrqarwwaqeitelaqgpgrdflqlhrhdsyapprpgtlarwfvngagyfaavadail
raqeeifitdwwlspevylkrpahsddwrldimlkrkaeegvrvsillfkevelalgins
gyskralmllhpnikvmrhpdqvtlwahhekllvvdqvvaflggldlaygrwddlhyrlt
dlgdssesaasqpptprpdspatpdlshnqffwlgkdysnlitkdwvqldrpfedfidre
ttprmpwrdvgvvvhglpardlarhfiqrwnftkttkakyktptypyllpkststanqlp
ftlpggqcttvqvlrsvdrwsagtlensilnaylhtiresqhflyienqffiscsdgrtv
lnkvgdeivdrilkahkqgwcyrvyvllpllpgfegdistgggnsiqailhftyrtlcrg
eysilhrlkaamgtawrdyisicglrthgelgghpvseliyihskvliaddrtviigsan
indrsllgkrdselavliedtetepslmngaeyqagrfalslrkhcfgvilgantrpdld
lrdpicddffqlwqdmaesnaniyeqifrclpsnatrslrtlreyvaveplatvspplar
seltqvqghlvhfplkfledesllpplgskegmiplevwt

    Sequence, based on observed residues (ATOM records):
    >6ohsA (A:)
rdflqlhrhdsyapprpgtlarwfvngagyfaavadailraqeeifitdwwlspevylkr
pahsddwrldimlkrkaeegvrvsillfkevelginsgyskralmllhpnikvmrhpdqv
tlwahhekllvvdqvvaflggldlaygrwddlhyrltdlgdlshnqffwlgkdysnlitk
dwvqldrpfedfidrettprmpwrdvgvvvhglpardlarhfiqrwnftkttkakyktpt
ypyllpkststlpggqcttvqvlrsvdrwsagtlensilnaylhtiresqhflyienqff
iscsdgrtvlnkvgdeivdrilkahkqgwcyrvyvllpllpgfegdistgggnsiqailh
ftyrtlcrgeysilhrlkaamgtawrdyisicglrthgelgghpvseliyihskvliadd
rtviigsanindrsllgkrdselavliedtetepslmngaeyqagrfalslrkhcfgvil
gantrpdldlrdpicddffqlwqdmaesnaniyeqifrclpsnatrslrtlreyvavepl
atvspplarseltqvqghlvhfplkfledesllppgmiplevwt

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6ohsB (B:)
ssyrqarwwaqeitelaqgpgrdflqlhrhdsyapprpgtlarwfvngagyfaavadail
raqeeifitdwwlspevylkrpahsddwrldimlkrkaeegvrvsillfkevelalgins
gyskralmllhpnikvmrhpdqvtlwahhekllvvdqvvaflggldlaygrwddlhyrlt
dlgdssesaasqpptprpdspatpdlshnqffwlgkdysnlitkdwvqldrpfedfidre
ttprmpwrdvgvvvhglpardlarhfiqrwnftkttkakyktptypyllpkststanqlp
ftlpggqcttvqvlrsvdrwsagtlensilnaylhtiresqhflyienqffiscsdgrtv
lnkvgdeivdrilkahkqgwcyrvyvllpllpgfegdistgggnsiqailhftyrtlcrg
eysilhrlkaamgtawrdyisicglrthgelgghpvseliyihskvliaddrtviigsan
indrsllgkrdselavliedtetepslmngaeyqagrfalslrkhcfgvilgantrpdld
lrdpicddffqlwqdmaesnaniyeqifrclpsnatrslrtlreyvaveplatvspplar
seltqvqghlvhfplkfledesllpplgskegmiplevwt

    Sequence, based on observed residues (ATOM records):
    >6ohsB (B:)
rdflqlhrhdsyapprpgtlarwfvngagyfaavadailraqeeifitdwwlspevylkr
pahsddwrldimlkrkaeegvrvsillfkevelginsgyskralmllhpnikvmrhpdqv
tlwahhekllvvdqvvaflggldlaygrwddlhyrltdlgdlshnqffwlgkdysnlitk
dwvqldrpfedfidrettprmpwrdvgvvvhglpardlarhfiqrwnftkttkakyktpt
ypyllpkststlpggqcttvqvlrsvdrwsagtlensilnaylhtiresqhflyienqff
iscsdgrtvlnkvgdeivdrilkahkqgwcyrvyvllpllpgfegdistgggnsiqailh
ftyrtlcrgeysilhrlkaamgtawrdyisicglrthgelgghpvseliyihskvliadd
rtviigsanindrsllgkrdselavliedtetepslmngaeyqagrfalslrkhcfgvil
gantrpdldlrdpicddffqlwqdmaesnaniyeqifrclpsnatrslrtlreyvavepl
atvspplarseltqvqghlvhfplkfledesllppgmiplevwt

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6ohsC (C:)
ssyrqarwwaqeitelaqgpgrdflqlhrhdsyapprpgtlarwfvngagyfaavadail
raqeeifitdwwlspevylkrpahsddwrldimlkrkaeegvrvsillfkevelalgins
gyskralmllhpnikvmrhpdqvtlwahhekllvvdqvvaflggldlaygrwddlhyrlt
dlgdssesaasqpptprpdspatpdlshnqffwlgkdysnlitkdwvqldrpfedfidre
ttprmpwrdvgvvvhglpardlarhfiqrwnftkttkakyktptypyllpkststanqlp
ftlpggqcttvqvlrsvdrwsagtlensilnaylhtiresqhflyienqffiscsdgrtv
lnkvgdeivdrilkahkqgwcyrvyvllpllpgfegdistgggnsiqailhftyrtlcrg
eysilhrlkaamgtawrdyisicglrthgelgghpvseliyihskvliaddrtviigsan
indrsllgkrdselavliedtetepslmngaeyqagrfalslrkhcfgvilgantrpdld
lrdpicddffqlwqdmaesnaniyeqifrclpsnatrslrtlreyvaveplatvspplar
seltqvqghlvhfplkfledesllpplgskegmiplevwt

    Sequence, based on observed residues (ATOM records):
    >6ohsC (C:)
rdflqlhrhdsyapprpgtlarwfvngagyfaavadailraqeeifitdwwlspevylkr
pahsddwrldimlkrkaeegvrvsillfkevelginsgyskralmllhpnikvmrhpdqv
tlwahhekllvvdqvvaflggldlaygrwddlhyrltdlgdlshnqffwlgkdysnlitk
dwvqldrpfedfidrettprmpwrdvgvvvhglpardlarhfiqrwnftkttkakyktpt
ypyllpkststlpggqcttvqvlrsvdrwsagtlensilnaylhtiresqhflyienqff
iscsdgrtvlnkvgdeivdrilkahkqgwcyrvyvllpllpgfegdistgggnsiqailh
ftyrtlcrgeysilhrlkaamgtawrdyisicglrthgelgghpvseliyihskvliadd
rtviigsanindrsllgkrdselavliedtetepslmngaeyqagrfalslrkhcfgvil
gantrpdldlrdpicddffqlwqdmaesnaniyeqifrclpsnatrslrtlreyvavepl
atvspplarseltqvqghlvhfplkfledesllppgmiplevwt

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6ohsD (D:)
ssyrqarwwaqeitelaqgpgrdflqlhrhdsyapprpgtlarwfvngagyfaavadail
raqeeifitdwwlspevylkrpahsddwrldimlkrkaeegvrvsillfkevelalgins
gyskralmllhpnikvmrhpdqvtlwahhekllvvdqvvaflggldlaygrwddlhyrlt
dlgdssesaasqpptprpdspatpdlshnqffwlgkdysnlitkdwvqldrpfedfidre
ttprmpwrdvgvvvhglpardlarhfiqrwnftkttkakyktptypyllpkststanqlp
ftlpggqcttvqvlrsvdrwsagtlensilnaylhtiresqhflyienqffiscsdgrtv
lnkvgdeivdrilkahkqgwcyrvyvllpllpgfegdistgggnsiqailhftyrtlcrg
eysilhrlkaamgtawrdyisicglrthgelgghpvseliyihskvliaddrtviigsan
indrsllgkrdselavliedtetepslmngaeyqagrfalslrkhcfgvilgantrpdld
lrdpicddffqlwqdmaesnaniyeqifrclpsnatrslrtlreyvaveplatvspplar
seltqvqghlvhfplkfledesllpplgskegmiplevwt

    Sequence, based on observed residues (ATOM records):
    >6ohsD (D:)
rdflqlhrhdsyapprpgtlarwfvngagyfaavadailraqeeifitdwwlspevylkr
pahsddwrldimlkrkaeegvrvsillfkevelginsgyskralmllhpnikvmrhpdqv
tlwahhekllvvdqvvaflggldlaygrwddlhyrltdlgdlshnqffwlgkdysnlitk
dwvqldrpfedfidrettprmpwrdvgvvvhglpardlarhfiqrwnftkttkakyktpt
ypyllpkststlpggqcttvqvlrsvdrwsagtlensilnaylhtiresqhflyienqff
iscsdgrtvlnkvgdeivdrilkahkqgwcyrvyvllpllpgfegdistgggnsiqailh
ftyrtlcrgeysilhrlkaamgtawrdyisicglrthgelgghpvseliyihskvliadd
rtviigsanindrsllgkrdselavliedtetepslmngaeyqagrfalslrkhcfgvil
gantrpdldlrdpicddffqlwqdmaesnaniyeqifrclpsnatrslrtlreyvavepl
atvspplarseltqvqghlvhfplkfledesllppgmiplevwt