PDB entry 6ofb

View 6ofb on RCSB PDB site
Description: crystal structure of human glutamine-dependent nad+ synthetase complexed with naad+, amp, pyrophosphate, and mg2+
Deposited on 2019-03-28, released 2020-01-08
The last revision was dated 2020-01-22, with a file datestamp of 2020-01-17.
Experiment type: XRAY
Resolution: 2.84 Å
R-factor: N/A
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glutamine-dependent NAD(+) synthetase
    Species: Homo sapiens [TaxId:9606]
    Gene: NADSYN1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6IA69
      • variant (74)
      • variant (204)
  • Chain 'B':
    Compound: Glutamine-dependent NAD(+) synthetase
    Species: Homo sapiens [TaxId:9606]
    Gene: NADSYN1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6IA69
      • variant (74)
      • variant (204)
  • Heterogens: AMP, MG, DND, POP, CL, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6ofbA (A:)
smgrkvtvatcalnqwaldfegnlqrilksieiaknrgaryrlgpeleicgygcwdhyye
sdtllhsfqvlaallespvtqdiicdvgmpvmhrnvryncrviflnrkillirpkmalan
egnyrelrwftpwsrsrhteeyflprmiqdltkqetvpfgdavlvtwdtcigseiceelw
tphsphidmgldgveiitnasgshhvlrkantrvdlvtmvtsknggiyllanqkgcdgdr
lyydgcamiamngsvfaqgsqfslddvevltatldledvrsyraeissrnlaasraspyp
rvkvdfalschedllapisepiewkyhspeeeislgpacwlwdflrrsqqagfllplsgg
vdsaatacliysmccqvceavrsgneevladvrtivnqisytpqdprdlcgrilttcyma
sknssqetctrarelaqqigshhislnidpavkavmgifslvtgksplfaahggssrenl
alqnvqarirmvlaylfaqlslwsrgvhggllvlgsanvdesllgyltkydcssadinpi
ggisktdlrafvqfciqrfqlpalqsillapataelepladgqvsqtdeedmgmtyaels
vygklrkvakmgpysmfckllgmwrhictprqvadkvkrffskysmnrhkmttltpayha
enyspednrfdlrpflyntswpwqfrcienqvlqleraepqsldgvd

    Sequence, based on observed residues (ATOM records):
    >6ofbA (A:)
rkvtvatcalnqwaldfegnlqrilksieiaknrgaryrlgpeleicgygcwdhyyesdt
llhsfqvlaallespvtqdiicdvgmpvmhrnvryncrviflnrkillirpkmalanegn
yrelrwftpwsrsrhteeyflprmiqdltkqetvpfgdavlvtwdtcigseiceelwtph
sphidmgldgveiitnasgshhvlrkantrvdlvtmvtsknggiyllanqkgcdgdrlyy
dgcamiamngsvfaqgsqfslddvevltatldledvrsyraeissrnlaasraspyprvk
vdfalschedllapisepiewkyhspeeeislgpacwlwdflrrsqqagfllplsggvds
aatacliysmccqvceavrsgneevladvrtivnqisytpqdprdlcgrilttcymaskn
ssqetctrarelaqqigshhislnidpavkavmgifslvtgksplfaahggssrenlalq
nvqarirmvlaylfaqlslwsrgvhggllvlgsanvdesllgyltkydcssadinpiggi
sktdlrafvqfciqrfqlpalqsillapataelepladgqvsqtdeedmgmtyaelsvyg
klrkvakmgpysmfckllgmwrhictprqvadkvkrffskysmnrhkmttltpayhaeny
spednrfdlrpflyntswpwqfrcienqvlqlerae

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6ofbB (B:)
smgrkvtvatcalnqwaldfegnlqrilksieiaknrgaryrlgpeleicgygcwdhyye
sdtllhsfqvlaallespvtqdiicdvgmpvmhrnvryncrviflnrkillirpkmalan
egnyrelrwftpwsrsrhteeyflprmiqdltkqetvpfgdavlvtwdtcigseiceelw
tphsphidmgldgveiitnasgshhvlrkantrvdlvtmvtsknggiyllanqkgcdgdr
lyydgcamiamngsvfaqgsqfslddvevltatldledvrsyraeissrnlaasraspyp
rvkvdfalschedllapisepiewkyhspeeeislgpacwlwdflrrsqqagfllplsgg
vdsaatacliysmccqvceavrsgneevladvrtivnqisytpqdprdlcgrilttcyma
sknssqetctrarelaqqigshhislnidpavkavmgifslvtgksplfaahggssrenl
alqnvqarirmvlaylfaqlslwsrgvhggllvlgsanvdesllgyltkydcssadinpi
ggisktdlrafvqfciqrfqlpalqsillapataelepladgqvsqtdeedmgmtyaels
vygklrkvakmgpysmfckllgmwrhictprqvadkvkrffskysmnrhkmttltpayha
enyspednrfdlrpflyntswpwqfrcienqvlqleraepqsldgvd

    Sequence, based on observed residues (ATOM records):
    >6ofbB (B:)
rkvtvatcalnqwaldfegnlqrilksieiaknrgaryrlgpeleicgygcwdhyyesdt
llhsfqvlaallespvtqdiicdvgmpvmhrnvryncrviflnrkillirpkmalanegn
yrelrwftpwsrsrhteeyflprmiqdltkqetvpfgdavlvtwdtcigseiceelwtph
sphidmgldgveiitnasgshhvlrkantrvdlvtmvtsknggiyllanqkgcdgdrlyy
dgcamiamngsvfaqgsqfslddvevltatldledvrsyraeissrnlaasraspyprvk
vdfalschedllapisepiewkyhspeeeislgpacwlwdflrrsqqagfllplsggvds
aatacliysmccqvceavrsgneevladvrtivnqisytpqdprdlcgrilttcymaskn
ssqetctrarelaqqigshhislnidpavkavmgifslvtgksplfaahggssrenlalq
nvqarirmvlaylfaqlslwsrgvhggllvlgsanvdesllgyltkydcssadinpiggi
sktdlrafvqfciqrfqlpalqsillapataelepladgqvsqtdeedmgmtyaelsvyg
klrkvakmgpysmfckllgmwrhictprqvadkvkrffskysmnrhkmttltpayhaeny
spednrfdlrpflyntswpwqfrcienqvlqlerae