PDB entry 6oen

View 6oen on RCSB PDB site
Description: cryo-em structure of mouse rag1/2 prc complex (dna1)
Deposited on 2019-03-27, released 2020-01-29
The last revision was dated 2020-02-26, with a file datestamp of 2020-02-21.
Experiment type: EM
Resolution: 4.3 Å
R-factor: N/A
AEROSPACI score: 0.02 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: V(D)J recombination-activating protein 1
    Species: Mus musculus [TaxId:10090]
    Gene: Rag1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15919
      • engineered mutation (961)
  • Chain 'B':
    Compound: V(D)J recombination-activating protein 2
    Species: Mus musculus [TaxId:10090]
    Gene: Rag2, Rag-2
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: V(D)J recombination-activating protein 1
    Species: Mus musculus [TaxId:10090]
    Gene: Rag1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15919
      • engineered mutation (961)
  • Chain 'D':
    Compound: V(D)J recombination-activating protein 2
    Species: Mus musculus [TaxId:10090]
    Gene: Rag2, Rag-2
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: DNA (46-mer)
    Species: ESCHERICHIA COLI K-12, synthetic [TaxId:83333]
  • Chain 'G':
    Compound: DNA (57-mer)
    Species: ESCHERICHIA COLI K-12, synthetic [TaxId:83333]
  • Chain 'H':
    Compound: High mobility group protein B1
    Species: Homo sapiens [TaxId:9606]
    Gene: HMGB1, HMG1
    Database cross-references and differences (RAF-indexed):
  • Chain 'I':
    Compound: DNA (46-mer)
    Species: ESCHERICHIA COLI K-12, synthetic [TaxId:83333]
  • Chain 'J':
    Compound: DNA (57-mer)
    Species: ESCHERICHIA COLI K-12, synthetic [TaxId:83333]
  • Chain 'N':
    Compound: High mobility group protein B1
    Species: Homo sapiens [TaxId:9606]
    Gene: HMGB1, HMG1
    Database cross-references and differences (RAF-indexed):
  • Heterogens: ZN, CA

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6oenA (A:)
maaslpstlsfssapdeiqhpqikfsewkfklfrvrsfekapeeaqkekdssegkpyleq
spvvpekpggqnsiltqralklhpkfskkfhadgkssdkavhqarlrhfcricgnrfksd
ghsrrypvhgpvdaktqslfrkkekrvtswpdliarifridvkadvdsihptefchdcws
imhrkfssshsqvyfprkvtvewhphtpscdicftahrglkrkrhqpnvqlskklktvln
harrdrrkrtqarvsskevlkkisncskihlstkllavdfpahfvksiscqicehiladp
vetsckhlfcricilrclkvmgsycpscrypcfptdlespvksflnilnslmvkcpaqdc
neevslekynhhvsshkesketlvhinkggrprqhllsltrraqkhrlrelkiqvkefad
keeggdvkavcltlfllalrarnehrqadeleaimqgrgsglqpavclairvntflscsq
yhkmyrtvkaitgrqifqplhalrnaekvllpgyhpfewqpplknvssrtdvgiidglsg
lassvdeypvdtiakrfrydsalvsalmdmeedilegmrsqdlddylngpftvvvkescd
gmgdvsekhgsgpavpekavrfsftvmritiehgsqnvkvfeepkpnselcckplclmla
desdhetltailspliaereamksseltlemggiprtfkfifrgtgydeklvreveglea
sgsvyictlcdttrleasqnlvfhsitrshaenlqryevwrsnpyhesveelrdrvkgvs
akpfietvpsidalhcdignaaefykifqleigevykhpnaskeerkrwqatldkhlrkr
mnlkpimrmngnfarklmtqetvdavcelipseerhealrelmdlylkmkpvwrsscpak
ecpeslcqysfnsqrfaellstkfkyryegkitnyfhktlahvpeiierdgsigawaseg
nqsgnklfrrfrkmnarqskcyemedvlkhhwlytskylqkfmnahnalkssgftmnske
tlgdplgiedslesqdsmef

    Sequence, based on observed residues (ATOM records):
    >6oenA (A:)
trraqkhrlrelkiqvkefadkeeggdvkavcltlfllalrarnehrqadeleaimqgrg
sglqpavclairvntflscsqyhkmyrtvkaitgrqifqplhalrnaekvllpgyhpfew
qpplknvssrtdvgiidglsglassvdeypvdtiakrfrydsalvsalmdmeedilegmr
sqdlddylngpftvvvkescdgmgdvsekhgsgpavpekavrfsftvmritiehgsqnvk
vfeepkpnselcckplclmladesdhetltailspliaereamksseltlemggiprtfk
fifrgtgydeklvrevegleasgsvyictlcdttrleasqnlvfhsitrshaenlqryev
wrsnpyhesveelrdrvkgvsakpfietvpsidalhcdignaaefykifqleigevykhp
naskeerkrwqatldkhlrkrmnlkpimrmngnfarklmtqetvdavcelipseerheal
relmdlylkmkpvwrsscpakecpeslcqysfnsqrfaellstkfkyryegkitnyfhkt
lahvpeiierdgsigawanqsgnklfrrfrkmnarqskcyemedvlkhhwlytskylqkf
mnahna

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6oenB (B:)
mslqmvtvghnialiqpgfslmnfdgqvfffgqkgwpkrscptgvfhfdikqnhlklkpa
ifskdscylpplrypatcsykgsidsdkhqyiihggktpnnelsdkiyimsvacknnkkv
tfrctekdlvgdvpepryghsidvvysrgksmgvlfggrsympstqrttekwnsvadclp
hvflidfefgcatsyilpelqdglsfhvsiarndtvyilgghslasnirpanlyrirvdl
plgtpavnctvlpggisvssailtqtnndefvivggyqlenqkrmvcslvslgdntieis
emetpdwtsdikhskiwfgsnmgngtiflgipgdnkqamseafyfytlrcseedlsedqk
ivsnsqtstedpgdstpfedseefcfsaeatsfdgddefdtyneddeddesvtgywitcc
ptcdvdintwvpfystelnkpamiycshgdghwvhaqcmdleertlihlsegsnkyycne
hvqiaralqtpkrnpplqkppmkslhkkgsgkvltpakksflrrlfd

    Sequence, based on observed residues (ATOM records):
    >6oenB (B:)
mslqmvtvghnialiqpgfslmnfdgqvfffgqkgwpkrscptgvfhfdikqnhlklkpa
ifskdscylpplrypatcsykgkhqyiihggktpnnelsdkiyimsvacknnkkvtfrct
ekdlvgdvpepryghsidvvysrgksmgvlfggrsympstqrttekwnsvadclphvfli
dfefgcatsyilpelqdglsfhvsiarndtvyilgghslasnirpanlyrirvdlplgtp
avnctvlpggisvssailtqtnndefvivggyqlenqkrmvcslvslgdntieisemetp
dwtsdikhskiwfgsnmgngtiflgipgdnkqamseafyfytlrcs

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6oenC (C:)
maaslpstlsfssapdeiqhpqikfsewkfklfrvrsfekapeeaqkekdssegkpyleq
spvvpekpggqnsiltqralklhpkfskkfhadgkssdkavhqarlrhfcricgnrfksd
ghsrrypvhgpvdaktqslfrkkekrvtswpdliarifridvkadvdsihptefchdcws
imhrkfssshsqvyfprkvtvewhphtpscdicftahrglkrkrhqpnvqlskklktvln
harrdrrkrtqarvsskevlkkisncskihlstkllavdfpahfvksiscqicehiladp
vetsckhlfcricilrclkvmgsycpscrypcfptdlespvksflnilnslmvkcpaqdc
neevslekynhhvsshkesketlvhinkggrprqhllsltrraqkhrlrelkiqvkefad
keeggdvkavcltlfllalrarnehrqadeleaimqgrgsglqpavclairvntflscsq
yhkmyrtvkaitgrqifqplhalrnaekvllpgyhpfewqpplknvssrtdvgiidglsg
lassvdeypvdtiakrfrydsalvsalmdmeedilegmrsqdlddylngpftvvvkescd
gmgdvsekhgsgpavpekavrfsftvmritiehgsqnvkvfeepkpnselcckplclmla
desdhetltailspliaereamksseltlemggiprtfkfifrgtgydeklvreveglea
sgsvyictlcdttrleasqnlvfhsitrshaenlqryevwrsnpyhesveelrdrvkgvs
akpfietvpsidalhcdignaaefykifqleigevykhpnaskeerkrwqatldkhlrkr
mnlkpimrmngnfarklmtqetvdavcelipseerhealrelmdlylkmkpvwrsscpak
ecpeslcqysfnsqrfaellstkfkyryegkitnyfhktlahvpeiierdgsigawaseg
nqsgnklfrrfrkmnarqskcyemedvlkhhwlytskylqkfmnahnalkssgftmnske
tlgdplgiedslesqdsmef

    Sequence, based on observed residues (ATOM records):
    >6oenC (C:)
hllsltrraqkhrlrelkiqvkefadkeeggdvkavcltlfllalrarnehrqadeleai
mqgrgsglqpavclairvntflscsqyhkmyrtvkaitgrqifqplhalrnaekvllpgy
hpfewqpplknvssrtdvgiidglsglassvdeypvdtiakrfrydsalvsalmdmeedi
legmrsqdlddylngpftvvvkescdgmgdvsekhgsgpavpekavrfsftvmritiehg
sqnvkvfeepkpnselcckplclmladesdhetltailspliaereamksseltlemggi
prtfkfifrgtgydeklvrevegleasgsvyictlcdttrleasqnlvfhsitrshaenl
qryevwrsnpyhesveelrdrvkgvsakpfietvpsidalhcdignaaefykifqleige
vykhpnaskeerkrwqatldkhlrkrmnlkpimrmngnfarklmtqetvdavcelipsee
rhealrelmdlylkmkpvwrsscpakecpeslcqysfnsqrfaellstkfkyryegkitn
yfhktlahvpeiierdgsiggnqsgnklfrrfrkmnarqskcyemedvlkhhwlytskyl
qkfmnahna

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6oenD (D:)
mslqmvtvghnialiqpgfslmnfdgqvfffgqkgwpkrscptgvfhfdikqnhlklkpa
ifskdscylpplrypatcsykgsidsdkhqyiihggktpnnelsdkiyimsvacknnkkv
tfrctekdlvgdvpepryghsidvvysrgksmgvlfggrsympstqrttekwnsvadclp
hvflidfefgcatsyilpelqdglsfhvsiarndtvyilgghslasnirpanlyrirvdl
plgtpavnctvlpggisvssailtqtnndefvivggyqlenqkrmvcslvslgdntieis
emetpdwtsdikhskiwfgsnmgngtiflgipgdnkqamseafyfytlrcseedlsedqk
ivsnsqtstedpgdstpfedseefcfsaeatsfdgddefdtyneddeddesvtgywitcc
ptcdvdintwvpfystelnkpamiycshgdghwvhaqcmdleertlihlsegsnkyycne
hvqiaralqtpkrnpplqkppmkslhkkgsgkvltpakksflrrlfd

    Sequence, based on observed residues (ATOM records):
    >6oenD (D:)
mslqmvtvghnialiqpgfslmnfdgqvfffgqkgwpkrscptgvfhfdikqnhlklkpa
ifskdscylpplrypatcsykgkhqyiihggktpnnelsdkiyimsvacknnkkvtfrct
ekdlvgdvpepryghsidvvysrgksmgvlfggrsympstqrttekwnsvadclphvfli
dfefgcatsyilpelqdglsfhvsiarndtvyilgghslasnirpanlyrirvdlplgtp
avnctvlpggisvssailtqtnndefvivggyqlenqkrmvcslvslgdntieisemetp
dwtsdikhskiwfgsnmgngtiflgipgdnkqamseafyfytlrcs

  • Chain 'F':
    No sequence available.

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6oenH (H:)
mgkgdpkkprgkmssyaffvqtcreehkkkhpdasvnfsefskkcserwktmsakekgkf
edmakadkaryeremktyippkgetkkkfkdpnapkrppsafflfcseyrpkikgehpgl
sigdvakklgemwnntaaddkqpyekkaaklkekyekdiaayr

    Sequence, based on observed residues (ATOM records):
    >6oenH (H:)
afflfcseyrpkikgehpglsigdvakklgemwnntaaddkqpyekkaaklkeky

  • Chain 'I':
    No sequence available.

  • Chain 'J':
    No sequence available.

  • Chain 'N':
    Sequence, based on SEQRES records:
    >6oenN (N:)
mgkgdpkkprgkmssyaffvqtcreehkkkhpdasvnfsefskkcserwktmsakekgkf
edmakadkaryeremktyippkgetkkkfkdpnapkrppsafflfcseyrpkikgehpgl
sigdvakklgemwnntaaddkqpyekkaaklkekyekdiaayr

    Sequence, based on observed residues (ATOM records):
    >6oenN (N:)
psafflfcseyrpkikgehpgigdvakklgemwnnt