PDB entry 6o8c

View 6o8c on RCSB PDB site
Description: crystal structure of sting ctt in complex with tbk1
Deposited on 2019-03-09, released 2019-05-22
The last revision was dated 2019-06-12, with a file datestamp of 2019-06-07.
Experiment type: XRAY
Resolution: 3.17 Å
R-factor: N/A
AEROSPACI score: 0.11 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein kinase TBK1
    Species: Mus musculus [TaxId:10090]
    Gene: Tbk1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9WUN2 (9-End)
      • expression tag (3-8)
  • Chain 'B':
    Compound: Serine/threonine-protein kinase TBK1
    Species: Mus musculus [TaxId:10090]
    Gene: Tbk1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9WUN2 (9-End)
      • expression tag (4-8)
  • Chain 'D':
    Compound: Stimulator of interferon genes protein
    Species: Homo sapiens [TaxId:9606]
    Gene: TMEM173, ERIS, MITA, STING
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Stimulator of interferon genes protein
    Species: Homo sapiens [TaxId:9606]
    Gene: TMEM173, ERIS, MITA, STING
    Database cross-references and differences (RAF-indexed):
  • Heterogens: BX7

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6o8cA (A:)
gspgldgicqstsnhlwllsdilgqgatanvfrgrhkktgdlyavkvfnnisflrpvdvq
mrefevlkklnhknivklfaieeetttrhkvlimefcpcgslytvleepsnayglpesef
livlrdvvggmnhlrengivhrdikpgnimrvigedgqsvykltdfgaareleddeqfva
lygteeylhpdmyeravlrkdhqkkygatvdlwsvgvtfyhaatgslpfrpfegprrnke
vmykiitgkpsgaisgvqkaengpidwsgdmplscslsqglqalltpvlanileadqekc
wgfdqffaetsdvlhrmvihvfslqhmtahkiyihsyntaavfhelvykqtkivssnqel
iyegrrlvlelgrlaqhfpktteenpifvtsreqlntvglryekislpkihprydldgda
smakavtgvvcyacrtastlllyqelmrkgvrwlvelvkddynetvhkktevvitldfci
rniektvkvyeklmkvnleaaelgeisdihtkllrlsssqgtiesslqdissrlspggll
adtwahqegthprdrnveklqvllnciteiyyqfkkdkaerrlayneeqihkfdkqklyy
hatkamshfseecvrkyeafkdkseewmrkmlhlrkqllsltnqcfdieeevskyqdytn
elqet

    Sequence, based on observed residues (ATOM records):
    >6o8cA (A:)
gldgicqstsnhlwllsdilgqgatanvfrgrhkktgdlyavkvfnnisflrpvdvqmre
fevlkklnhknivklfaieeetttrhkvlimefcpcgslytvleepsnayglpesefliv
lrdvvggmnhlrengivhrdikpgnimrvigedgqsvykltdfgaateeylhpdmyerav
lrkdhqkkygatvdlwsvgvtfyhaatgslpfrpfegprrnkevmykiitgkpsgaisgv
qkaengpidwsgdmplscslsqglqalltpvlanileadqekcwgfdqffaetsdvlhrm
vihvfslqhmtahkiyihsyntaavfhelvykqtkivssnqeliyegrrlvlelgrlaqh
fpktteenpifvtsreqlntvglryekislpkihprydldgdasmakavtgvvcyacrta
stlllyqelmrkgvrwlvelvkddynetvhkktevvitldfcirniektvkvvnleaael
geisdihtkllrlsssqgtiesslqdissrlspgglladtwahqegthprdrnveklqvl
lnciteiyyqfkkdkaerrlayneeqihkfdkqklyyhatkamshfseecvrkyeafkdk
seewmrkmlhlrkqllsltnqcfdieeevskyqdyt

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6o8cB (B:)
gspgldgicqstsnhlwllsdilgqgatanvfrgrhkktgdlyavkvfnnisflrpvdvq
mrefevlkklnhknivklfaieeetttrhkvlimefcpcgslytvleepsnayglpesef
livlrdvvggmnhlrengivhrdikpgnimrvigedgqsvykltdfgaareleddeqfva
lygteeylhpdmyeravlrkdhqkkygatvdlwsvgvtfyhaatgslpfrpfegprrnke
vmykiitgkpsgaisgvqkaengpidwsgdmplscslsqglqalltpvlanileadqekc
wgfdqffaetsdvlhrmvihvfslqhmtahkiyihsyntaavfhelvykqtkivssnqel
iyegrrlvlelgrlaqhfpktteenpifvtsreqlntvglryekislpkihprydldgda
smakavtgvvcyacrtastlllyqelmrkgvrwlvelvkddynetvhkktevvitldfci
rniektvkvyeklmkvnleaaelgeisdihtkllrlsssqgtiesslqdissrlspggll
adtwahqegthprdrnveklqvllnciteiyyqfkkdkaerrlayneeqihkfdkqklyy
hatkamshfseecvrkyeafkdkseewmrkmlhlrkqllsltnqcfdieeevskyqdytn
elqet

    Sequence, based on observed residues (ATOM records):
    >6o8cB (B:)
ldgicqstsnhlwllsdilgqgatanvfrgrhkktgdlyavkvfnnisflrpvdvqmref
evlkklnhknivklfaieeetttrhkvlimefcpcgslytvleepsnayglpeseflivl
rdvvggmnhlrengivhrdikpgnimrvigedgqsvykltdfgagteeylhpdmyeravl
rkdhqkkygatvdlwsvgvtfyhaatgslpfrpfegprrnkevmykiitgkpsgaisgvq
kaengpidwsgdmplscslsqglqalltpvlanileadqekcwgfdqffaetsdvlhrmv
ihvfslqhmtahkiyihsyntaavfhelvykqtkivssnqeliyegrrlvlelgrlaqhf
pktteenpifvtsreqlntvglryekislpkihprydldgdasmakavtgvvcyacrtas
tlllyqelmrkgvrwlvelvkddynetvhkktevvitldfcirniektvkvyeklmkvnl
eaaelgeisdihtkllrlsssqgtiesslqdissrlspgglladtwahqegthprdrnve
klqvllnciteiyyqfkkdkaerrlayneeqihkfdkqklyyhatkamshfseecvrkye
afkdkseewmrkmlhlrkqllsltnqcfdieeevskyqdytne

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6o8cD (D:)
stwgslktsavpststmsqepellisgmekplplrtdfs

    Sequence, based on observed residues (ATOM records):
    >6o8cD (D:)
sgmekplplrtdfs

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6o8cE (E:)
stwgslktsavpststmsqepellisgmekplplrtdfs

    Sequence, based on observed residues (ATOM records):
    >6o8cE (E:)
mekplplrtdfs