PDB entry 6o6f

View 6o6f on RCSB PDB site
Description: Co-crystal structure of Mcl1 with inhibitor
Class: apoptosis/inhibitor
Keywords: apoptosis, inhibition, APOPTOSIS-INHIBITOR complex
Deposited on 2019-03-06, released 2019-05-15
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-05-15, with a file datestamp of 2019-05-10.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: N/A
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Induced myeloid leukemia cell differentiation protein Mcl-1
    Species: Homo sapiens [TaxId:9606]
    Gene: MCL1, BCL2L3
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q07820 (2-End)
      • expression tag (1)
    Domains in SCOPe 2.08: d6o6fa1, d6o6fa2
  • Chain 'B':
    Compound: Induced myeloid leukemia cell differentiation protein Mcl-1
    Species: Homo sapiens [TaxId:9606]
    Gene: MCL1, BCL2L3
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q07820 (2-End)
      • expression tag (1)
    Domains in SCOPe 2.08: d6o6fb1, d6o6fb2
  • Heterogens: LOD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6o6fA (A:)
gsdelyrqsleiisrylreqatgakdtkpmgrsgatsrkaletlrrvgdgvqrnhetafq
gmlrkldikneddvkslsrvmihvfsdgvtnwgrivtlisfgafvakhlktinqesciep
laesitdvlvrtkrdwlvkqrgwdgfveffhvedlegg

    Sequence, based on observed residues (ATOM records): (download) 
    >6o6fA (A:)
sdelyrqsleiisrylreqatgakdtkpmgrsgatsrkaletlrrvgdgvqrnhetafqg
mlrkldikneddvkslsrvmihvfsdgvtnwgrivtlisfgafvakhlktinqesciepl
aesitdvlvrtkrdwlvkqrgwdgfveffhv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6o6fB (B:)
gsdelyrqsleiisrylreqatgakdtkpmgrsgatsrkaletlrrvgdgvqrnhetafq
gmlrkldikneddvkslsrvmihvfsdgvtnwgrivtlisfgafvakhlktinqesciep
laesitdvlvrtkrdwlvkqrgwdgfveffhvedlegg

    Sequence, based on observed residues (ATOM records): (download) 
    >6o6fB (B:)
sdelyrqsleiisrylreqatgakdtkpmgsgatsrkaletlrrvgdgvqrnhetafqgm
lrkldikneddvkslsrvmihvfsdgvtnwgrivtlisfgafvakhlktinqesciepla
esitdvlvrtkrdwlvkqrgwdgfveffhv