PDB entry 6o5i

View 6o5i on RCSB PDB site
Description: Menin in complex with MI-3454
Class: protein binding
Keywords: Menin-inhibitor complex, PROTEIN BINDING
Deposited on 2019-03-03, released 2020-01-08
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-02-19, with a file datestamp of 2020-02-14.
Experiment type: XRAY
Resolution: 1.24 Å
R-factor: N/A
AEROSPACI score: 0.63 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Menin
    Species: Homo sapiens [TaxId:9606]
    Gene: MEN1, SCG2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6o5ia1, d6o5ia2, d6o5ia3
  • Heterogens: LMY, DMS, SO4, PG4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6o5iA (A:)
ggsssmglkaaqktlfplrsiddvvrlfaaelgreepdlvllslvlgfvehflavnrvgl
tyfpvadlsiiaalyarftaqirgavdlslypreggvssrelvkkvsdviwnslsrsyfk
drahiqslfsfitgtkldssgvafavvgacqalglrdvhlalsedhawvvfgpngeqtae
vtwhgkgnedrrgqtvnagvaerswlylkgsymrcdrkmevafmvcainpsidlhtdsle
llqlqqkllwllydlghlerypmalgnladleeleptpgrpdpltlyhkgiasaktyyrd
ehiypymylagyhcrnrnvrealqawadtatviqdynycredeeiykeffevandvipnl
lkeaaslleagsqgsalqdpecfahllrfydgickweegsptpvlhvgwatflvqslgrf
egqvrqkvrivsvpaptaspppegpvltfqsekmkgmkellvatkinssaiklqltaqsq
vqmkkqkvs

    Sequence, based on observed residues (ATOM records): (download) 
    >6o5iA (A:)
glkaaqktlfplrsiddvvrlfaaelgreepdlvllslvlgfvehflavnrvgltyfpva
dlsiiaalyarftaqirgavdlslypreggvssrelvkkvsdviwnslsrsyfkdrahiq
slfsfitgtkldssgvafavvgacqalglrdvhlalsedhawvvfgpngeqtaevtwhgk
gnedrrgqtvnagvaerswlylkgsymrcdrkmevafmvcainpsidlhtdslellqlqq
kllwllydlghlerypmalgnladleeleptpgrpdpltlyhkgiasaktyyrdehiypy
mylagyhcrnrnvrealqawadtatviqdynycredeeiykeffevandvipnllkeaas
lleagsqgsalqdpecfahllrfydgickweegsptpvlhvgwatflvqslgrfegqvrq
kvrivspvltfqsekmkgmkellvatkinssaiklqltaqsqvqmk