PDB entry 6o4x

View 6o4x on RCSB PDB site
Description: Binary complex of native hAChE with 9-aminoacridine
Class: hydrolase
Keywords: hydrolase
Deposited on 2019-03-01, released 2019-06-19
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-02-19, with a file datestamp of 2020-02-14.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: acetylcholinesterase
    Species: Homo sapiens [TaxId:9606]
    Gene: ACHE
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6o4xa_
  • Chain 'B':
    Compound: acetylcholinesterase
    Species: Homo sapiens [TaxId:9606]
    Gene: ACHE
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6o4xb_
  • Heterogens: GOL, NO3, AA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6o4xA (A:)
gplegredaellvtvrggrlrgirlktpggpvsaflgipfaeppmgprrflppepkqpws
gvvdattfqsvcyqyvdtlypgfegtemwnpnrelsedclylnvwtpyprptsptpvlvw
iygggfysgassldvydgrflvqaertvlvsmnyrvgafgflalpgsreapgnvglldqr
lalqwvqenvaafggdptsvtlfgesagaasvgmhllsppsrglfhravlqsgapngpwa
tvgmgearrratqlahlvgcppggtggndtelvaclrtrpaqvlvnhewhvlpqesvfrf
sfvpvvdgdflsdtpealinagdfhglqvlvgvvkdegsyflvygapgfskdneslisra
eflagvrvgvpqvsdlaaeavvlhytdwlhpedparlrealsdvvgdhnvvcpvaqlagr
laaqgarvyayvfehrastlswplwmgvphgyeiefifgipldpsrnytaeekifaqrlm
rywanfartgdpneprdpkapqwppytagaqqyvsldlrplevrrglraqacafwnrflp
kllsatdtld

    Sequence, based on observed residues (ATOM records): (download) 
    >6o4xA (A:)
edaellvtvrggrlrgirlktpggpvsaflgipfaeppmgprrflppepkqpwsgvvdat
tfqsvcyqyvdtlypgfegtemwnpnrelsedclylnvwtpyprptsptpvlvwiygggf
ysgassldvydgrflvqaertvlvsmnyrvgafgflalpgsreapgnvglldqrlalqwv
qenvaafggdptsvtlfgesagaasvgmhllsppsrglfhravlqsgapngpwatvgmge
arrratqlahlvgcppggtggndtelvaclrtrpaqvlvnhewhvlpqesvfrfsfvpvv
dgdflsdtpealinagdfhglqvlvgvvkdegsyflvygapgfskdneslisraeflagv
rvgvpqvsdlaaeavvlhytdwlhpedparlrealsdvvgdhnvvcpvaqlagrlaaqga
rvyayvfehrastlswplwmgvphgyeiefifgipldpsrnytaeekifaqrlmrywanf
artgdpneprdpkapqwppytagaqqyvsldlrplevrrglraqacafwnrflpkllsat

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6o4xB (B:)
gplegredaellvtvrggrlrgirlktpggpvsaflgipfaeppmgprrflppepkqpws
gvvdattfqsvcyqyvdtlypgfegtemwnpnrelsedclylnvwtpyprptsptpvlvw
iygggfysgassldvydgrflvqaertvlvsmnyrvgafgflalpgsreapgnvglldqr
lalqwvqenvaafggdptsvtlfgesagaasvgmhllsppsrglfhravlqsgapngpwa
tvgmgearrratqlahlvgcppggtggndtelvaclrtrpaqvlvnhewhvlpqesvfrf
sfvpvvdgdflsdtpealinagdfhglqvlvgvvkdegsyflvygapgfskdneslisra
eflagvrvgvpqvsdlaaeavvlhytdwlhpedparlrealsdvvgdhnvvcpvaqlagr
laaqgarvyayvfehrastlswplwmgvphgyeiefifgipldpsrnytaeekifaqrlm
rywanfartgdpneprdpkapqwppytagaqqyvsldlrplevrrglraqacafwnrflp
kllsatdtld

    Sequence, based on observed residues (ATOM records): (download) 
    >6o4xB (B:)
edaellvtvrggrlrgirlktpggpvsaflgipfaeppmgprrflppepkqpwsgvvdat
tfqsvcyqyvdtlypgfegtemwnpnrelsedclylnvwtpyprptsptpvlvwiygggf
ysgassldvydgrflvqaertvlvsmnyrvgafgflalpgsreapgnvglldqrlalqwv
qenvaafggdptsvtlfgesagaasvgmhllsppsrglfhravlqsgapngpwatvgmge
arrratqlahlvgcppggtggndtelvaclrtrpaqvlvnhewhvlpqesvfrfsfvpvv
dgdflsdtpealinagdfhglqvlvgvvkdegsyflvygapgfskdneslisraeflagv
rvgvpqvsdlaaeavvlhytdwlhpedparlrealsdvvgdhnvvcpvaqlagrlaaqga
rvyayvfehrastlswplwmgvphgyeiefifgipldpsrnytaeekifaqrlmrywanf
artgdpneprdpkapqwppytagaqqyvsldlrplevrrglraqacafwnrflpkllsat