PDB entry 6o4u

View 6o4u on RCSB PDB site
Description: Co-crystal structure of Mcl1 with inhibitor
Class: apoptosis/inhibitor
Keywords: Inhibitor, APOPTOSIS, APOPTOSIS-INHIBITOR complex
Deposited on 2019-03-01, released 2020-03-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-03-04, with a file datestamp of 2020-02-28.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Induced myeloid leukemia cell differentiation protein Mcl-1
    Species: Homo sapiens [TaxId:9606]
    Gene: MCL1, BCL2L3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6o4ua_
  • Chain 'B':
    Compound: Induced myeloid leukemia cell differentiation protein Mcl-1
    Species: Homo sapiens [TaxId:9606]
    Gene: MCL1, BCL2L3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6o4ub_
  • Heterogens: LMV, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6o4uA (A:)
delyrqsleiisrylreqatgakdtkpmgrsgatsrkaletlrrvgdgvqrnhetafqgm
lrkldikneddvkslsrvmihvfsdgvtnwgrivtlisfgafvakhlktinqesciepla
esitdvlvrtkrdwlvkqrgwdgfveffhvedlegg

    Sequence, based on observed residues (ATOM records): (download) 
    >6o4uA (A:)
delyrqsleiisrylreqatgakdgrsgatsrkaletlrrvgdgvqrnhetafqgmlrkl
dikneddvkslsrvmihvfsdgvtnwgrivtlisfgafvakhlktinqescieplaesit
dvlvrtkrdwlvkqrgwdgfveffhv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6o4uB (B:)
delyrqsleiisrylreqatgakdtkpmgrsgatsrkaletlrrvgdgvqrnhetafqgm
lrkldikneddvkslsrvmihvfsdgvtnwgrivtlisfgafvakhlktinqesciepla
esitdvlvrtkrdwlvkqrgwdgfveffhvedlegg

    Sequence, based on observed residues (ATOM records): (download) 
    >6o4uB (B:)
delyrqsleiisrylreqatgakdtkpmgrsgatsrkaletlrrvgdgvqrnhetafqgm
lrkldikneddvkslsrvmihvfsdgvtnwgrivtlisfgafvakhlktinqesciepla
esitdvlvrtkrdwlvkqrgwdgfveffhv