PDB entry 6o3j

View 6o3j on RCSB PDB site
Description: crystal structure of the fab fragment of the human hiv-1 neutralizing antibody pgzl1 in complex with its mper peptide epitope (region 671- 683 of hiv-1 gp41) and phosphatidic acid (06:0 pa)
Deposited on 2019-02-26, released 2019-12-04
The last revision was dated 2019-12-11, with a file datestamp of 2019-12-06.
Experiment type: XRAY
Resolution: 3.42 Å
R-factor: N/A
AEROSPACI score: 0.1 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: PGZL1 heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6O3J (0-End)
  • Chain 'B':
    Compound: PGZL1 light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6O3J
  • Chain 'G':
    Compound: MPER peptide, region 671-683 of HIV-1 gp41
    Species: Human immunodeficiency virus 1, synthetic [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
    • PDB 6O3J (0-End)
  • Chain 'H':
    Compound: PGZL1 heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6O3J (0-End)
  • Chain 'I':
    Compound: MPER peptide, region 671-683 of HIV-1 gp41
    Species: Human immunodeficiency virus 1, synthetic [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
    • PDB 6O3J (0-15)
  • Chain 'L':
    Compound: PGZL1 light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6O3J
  • Heterogens: 44E, MPD

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6o3jA (A:)
evqlvqsggevkrpgssvtvsckatggtfstlafnwvrqapgqgpewmggivplfsivny
gqkfqgrltiradkstttvfldlsgltsadtatyycaregegwfgkplrafefwgqgtvi
tvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpav
lqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepksc

    Sequence, based on observed residues (ATOM records):
    >6o3jA (A:)
evqlvqsggevkrpgssvtvsckatggtfstlafnwvrqapgqgpewmggivplfsivny
gqkfqgrltiradkstttvfldlsgltsadtatyycaregegwfgkplrafefwgqgtvi
tvssastkgpsvfplapssgtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssg
lyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6o3jB (B:)
dvvmtqspgtlslspgeratlscrasqsvsggalawyqqkpgqaprlliydtssrptgvp
grfsgsgsgtdfsltisrlepedfavyycqqygtsqstfgqgtrleikrtvaapsvfifp
psdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstl
tlskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records):
    >6o3jB (B:)
vvmtqspgtlslspgeratlscrasqsvsggalawyqqkpgqaprlliydtssrptgvpg
rfsgsgsgtdfsltisrlepedfavyycqqygtsqstfgqgtrleikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrg

  • Chain 'G':
    Sequence, based on SEQRES records:
    >6o3jG (G:)
nwfditnwlwyikkkk

    Sequence, based on observed residues (ATOM records):
    >6o3jG (G:)
nwfditnwlwyikkk

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6o3jH (H:)
evqlvqsggevkrpgssvtvsckatggtfstlafnwvrqapgqgpewmggivplfsivny
gqkfqgrltiradkstttvfldlsgltsadtatyycaregegwfgkplrafefwgqgtvi
tvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpav
lqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepksc

    Sequence, based on observed residues (ATOM records):
    >6o3jH (H:)
evqlvqsggevkrpgssvtvsckatggtfstlafnwvrqapgqgpewmggivplfsivny
gqkfqgrltiradkstttvfldlsgltsadtatyycaregegwfgkplrafefwgqgtvi
tvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpav
lqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk

  • Chain 'I':
    Sequence; same for both SEQRES and ATOM records:
    >6o3jI (I:)
nwfditnwlwyikkkk

  • Chain 'L':
    Sequence, based on SEQRES records:
    >6o3jL (L:)
dvvmtqspgtlslspgeratlscrasqsvsggalawyqqkpgqaprlliydtssrptgvp
grfsgsgsgtdfsltisrlepedfavyycqqygtsqstfgqgtrleikrtvaapsvfifp
psdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstl
tlskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records):
    >6o3jL (L:)
vvmtqspgtlslspgeratlscrasqsvsggalawyqqkpgqaprlliydtssrptgvpg
rfsgsgsgtdfsltisrlepedfavyycqqygtsqstfgqgtrleikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrge