PDB entry 6o3f

View 6o3f on RCSB PDB site
Description: Crystal Structure of Lysyl-tRNA Synthetase from Chlamydia trachomatis with complexed with L-lysine and a difluoro cyclohexyl chromone ligand
Class: ligase
Keywords: SSGCID, KRS, nucleotide binding, Aminoacyl TRNA Ligase Activity, Lysine TRNA Ligase Activity, ATP Binding, Lysyl TRNA Aminoacylation, strain UCH-1/proctitis, strain D/UW-3/Cx, Structural Genomics, Seattle Structural Genomics Center for Infectious Disease, LIGASE
Deposited on 2019-02-26, released 2019-03-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-03-11, with a file datestamp of 2020-03-06.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Lysine--tRNA ligase
    Species: Chlamydia trachomatis serovar L2b (strain UCH-1/proctitis) [TaxId:471473]
    Gene: lysS, CTLon_0150
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6o3fa1, d6o3fa2
  • Chain 'B':
    Compound: Lysine--tRNA ligase
    Species: Chlamydia trachomatis serovar L2b (strain UCH-1/proctitis) [TaxId:471473]
    Gene: lysS, CTLon_0150
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6o3fb1, d6o3fb2
  • Heterogens: FYB, EDO, SO4, PEG, LYS, PG4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6o3fA (A:)
mahhhhhhmsveveylqhedylyrtsklkeirdlginpypyqytdclevqeirnqfvdne
lgdseaafrketpkvrfagrlvlfrsmgknafgqildndakiqvmfnrdfsavaglaada
gispikfiekkldlgdilglegylffthsgeltvlvetvtllckslislpdkhagladke
iryrkrwadlissedvrktfltrsrilklireymdqqsflevetpilqtvyggaeatpfv
ttlqalhaemflrisleialkkllvggmsrvyeigkvfrnegidrthnpeftmieayaay
wdyndvmkcvenlveyivralnngetqvqyshlksgpqvvdfkapwirmtmkesisvygg
vdvdlhadhelrkiletqtslpektyvhasrgeliallfdelvcdkliaphhitdhplet
tplcktlrsgdetlverfesfclgkelcnayselndplqqrklleeqmrkkalnpdseyh
pideeflealcqgmppaggfgigidrlvmmltdaasirdvlffpvmrri

    Sequence, based on observed residues (ATOM records): (download) 
    >6o3fA (A:)
eveylqhedylyrtsklkeirdlginpypyqytdclevqeirnqfvdnelgdseaafrke
tpkvrfagrlvlfrsmgknafgqildndakiqvmfnrdfsavaglaadagispikfiekk
ldlgdilglegylffthsgeltvlvetvtllckslislpdkhagladkeiryrkrwadli
ssedvrktfltrsrilklireymdqqsflevetpilqtvyggaeatpfvttlqalhaemf
lrisleialkkllvggmsrvyeigkvfrnegidrthnpeftmieayaaywdyndvmkcve
nlveyivralnngetqvqyshlksgpqvvdfkapwirmtmkesisvyggvdvdlhadhel
rkiletqtslpektyvhasrgeliallfdelvcdkliaphhitdhplettplcktlrsgd
etlverfesfclgkelcnayselndplqqrklleeqmrkkalnpdseyhpideeflealc
qgmppaggfgigidrlvmmltdaasirdvlffpvmrr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6o3fB (B:)
mahhhhhhmsveveylqhedylyrtsklkeirdlginpypyqytdclevqeirnqfvdne
lgdseaafrketpkvrfagrlvlfrsmgknafgqildndakiqvmfnrdfsavaglaada
gispikfiekkldlgdilglegylffthsgeltvlvetvtllckslislpdkhagladke
iryrkrwadlissedvrktfltrsrilklireymdqqsflevetpilqtvyggaeatpfv
ttlqalhaemflrisleialkkllvggmsrvyeigkvfrnegidrthnpeftmieayaay
wdyndvmkcvenlveyivralnngetqvqyshlksgpqvvdfkapwirmtmkesisvygg
vdvdlhadhelrkiletqtslpektyvhasrgeliallfdelvcdkliaphhitdhplet
tplcktlrsgdetlverfesfclgkelcnayselndplqqrklleeqmrkkalnpdseyh
pideeflealcqgmppaggfgigidrlvmmltdaasirdvlffpvmrri

    Sequence, based on observed residues (ATOM records): (download) 
    >6o3fB (B:)
veylqhedylyrtsklkeirdlginpypyqytdclevqeirnqfvdnelgdseaafrket
pkvrfagrlvlfrsmgknafgqildndakiqvmfnrdfsavaglaadagispikfiekkl
dlgdilglegylffthsgeltvlvetvtllckslislpdkhagladkeiryrkrwadlis
sedvrktfltrsrilklireymdqqsflevetpilqtvyggaeatpfvttlqalhaemfl
risleialkkllvggmsrvyeigkvfrnegidrthnpeftmieayaaywdyndvmkcven
lveyivralnngetqvqyshlksgpqvvdfkapwirmtmkesisvyggvdvdlhadhelr
kiletqtslpektyvhasrgeliallfdelvcdkliaphhitdhplettplcktlrsgde
tlverfesfclgkelcnayselndplqqrklleeqmrkkalnpdseyhpideeflealcq
gmppaggfgigidrlvmmltdaasirdvlffpvmrri