PDB entry 6o2w

View 6o2w on RCSB PDB site
Description: crystal structure of the saraf luminal domain cys-lock mutant dimer
Deposited on 2019-02-24, released 2019-05-29
The last revision was dated 2019-12-04, with a file datestamp of 2019-11-29.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Store-operated calcium entry-associated regulatory factor
    Species: Homo sapiens [TaxId:9606]
    Gene: SARAF, TMEM66, XTP3, HSPC035, NPD003, PSEC0019, UNQ1967/PRO4499
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q96BY9 (Start-134)
      • engineered mutation (68)
      • engineered mutation (126)
  • Chain 'B':
    Compound: Store-operated calcium entry-associated regulatory factor
    Species: Homo sapiens [TaxId:9606]
    Gene: SARAF, TMEM66, XTP3, HSPC035, NPD003, PSEC0019, UNQ1967/PRO4499
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q96BY9 (Start-134)
      • engineered mutation (68)
      • engineered mutation (126)
  • Heterogens: GOL, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6o2wA (A:)
gwndpdrmllrdvkaltlhydryttsrrldpipqlkcvggtagcdsytpkviqcqnkgwd
gydvqwecctdldiaykfgktvvscegyessedqyvlrgscgleynldytelglqklkes
gkqhgfcsfsdyyyk

    Sequence, based on observed residues (ATOM records):
    >6o2wA (A:)
pdrmllrdvkaltlhydryttsrrldpipqlkcvggtagcdsytpkviqcqnkgwddvqw
ecctdldiaykfgktvvscegyessedqyvlrgscgleynldytelglqklkesgkqhgf
csfsdyyyk

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6o2wB (B:)
gwndpdrmllrdvkaltlhydryttsrrldpipqlkcvggtagcdsytpkviqcqnkgwd
gydvqwecctdldiaykfgktvvscegyessedqyvlrgscgleynldytelglqklkes
gkqhgfcsfsdyyyk

    Sequence, based on observed residues (ATOM records):
    >6o2wB (B:)
pdrmllrdvkaltlhydryttsrrldpipqlkcvggtagcdsytpkviqcqnkgwddvqw
ecctdldiaykfgktvvscegyessedqyvlrgscgleynldytelglqklkesgkqhgf
csfsdyyyk