PDB entry 6o1u

View 6o1u on RCSB PDB site
Description: cryo-em structure of trpv5 w583a in nanodisc
Deposited on 2019-02-21, released 2019-04-24
The last revision was dated 2019-12-18, with a file datestamp of 2019-12-13.
Experiment type: EM
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Transient receptor potential cation channel subfamily V member 5
    Species: Oryctolagus cuniculus [TaxId:9986]
    Gene: Trpv5, Ecac1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9XSM3
      • engineered mutation (582)
  • Chain 'B':
    Compound: Transient receptor potential cation channel subfamily V member 5
    Species: Oryctolagus cuniculus [TaxId:9986]
    Gene: Trpv5, Ecac1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9XSM3
      • engineered mutation (582)
  • Chain 'C':
    Compound: Transient receptor potential cation channel subfamily V member 5
    Species: Oryctolagus cuniculus [TaxId:9986]
    Gene: Trpv5, Ecac1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9XSM3
      • engineered mutation (582)
  • Chain 'D':
    Compound: Transient receptor potential cation channel subfamily V member 5
    Species: Oryctolagus cuniculus [TaxId:9986]
    Gene: Trpv5, Ecac1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9XSM3
      • engineered mutation (582)

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6o1uA (A:)
mgacppkakgpwaqlqklliswpvgeqdweqyrdrvnmlqqerirdspllqaakendlrl
lkilllnqscdfqqrgavgetalhvaalydnleaatllmeaapelakepalcepfvgqta
lhiavmnqnlnlvrallargasvsaratgaafrrsphnliyygehplsfaacvgseeivr
lliehgadiraqdslgntvlhililqpnktfacqmynlllsydehsdhlqslelvpnhqg
ltpfklagvegntvmfqhlmqkrkhvqwtcgpltstlydlteidswgeelsflelvvssk
krearqileqtpvkelvsfkwkkygrpyfcvlaslyilymicfttcciyrplklrddnrt
dprditilqqkllqeayvthqdnirlvgelvtvtgaviillleipdifrvgasryfgqti
lggpfhviiityaslvlltmvmrltnmngevvplsfalvlgwcsvmyfargfqmlgpfti
miqkmifgdlmrfcwlmavvilgfasafhitfqtedpnnlgefsdyptalfstfelflti
idgpanysvdlpfmycityaafaiiatllmlnlfiammgdtharvaqerdelwraqvvat
tvmlerkmprflwprsgicgyeyglgdrwflrvenhhdqnplrvlryveafkcsdkedgq
eqlsekrpstvesgmlsrasvafqtpslsrttsqssnshrgweilrrntlghlnlgldlg
egdgeevyhf

    Sequence, based on observed residues (ATOM records):
    >6o1uA (A:)
geqdweqyrdrvnmlqqerirdspllqaakendlrllkilllnqscdfqqrgavgetalh
vaalydnleaatllmeaapelakepalcepfvgqtalhiavmnqnlnlvrallargasvs
aratgaafrrsphnliyygehplsfaacvgseeivrlliehgadiraqdslgntvlhili
lqpnktfacqmynlllsydehsdhlqslelvpnhqgltpfklagvegntvmfqhlmqkrk
hvqwtcgpltstlydlteidswgeelsflelvvsskkrearqileqtpvkelvsfkwkky
grpyfcvlaslyilymicfttcciyrplklrddnrtdprditilqqkllqeayvthqdni
rlvgelvtvtgaviillleipdifrvgasryfgqtilggpfhviiityaslvlltmvmrl
tnmngevvplsfalvlgwcsvmyfargfqmlgpftimiqkmifgdlmrfcwlmavvilgf
asafhitfqtedpnnlgefsdyptalfstfelfltiidgpanysvdlpfmycityaafai
iatllmlnlfiammgdtharvaqerdelwraqvvattvmlerkmprflwprsgicgyeyg
lgdrwflrvenhhd

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6o1uB (B:)
mgacppkakgpwaqlqklliswpvgeqdweqyrdrvnmlqqerirdspllqaakendlrl
lkilllnqscdfqqrgavgetalhvaalydnleaatllmeaapelakepalcepfvgqta
lhiavmnqnlnlvrallargasvsaratgaafrrsphnliyygehplsfaacvgseeivr
lliehgadiraqdslgntvlhililqpnktfacqmynlllsydehsdhlqslelvpnhqg
ltpfklagvegntvmfqhlmqkrkhvqwtcgpltstlydlteidswgeelsflelvvssk
krearqileqtpvkelvsfkwkkygrpyfcvlaslyilymicfttcciyrplklrddnrt
dprditilqqkllqeayvthqdnirlvgelvtvtgaviillleipdifrvgasryfgqti
lggpfhviiityaslvlltmvmrltnmngevvplsfalvlgwcsvmyfargfqmlgpfti
miqkmifgdlmrfcwlmavvilgfasafhitfqtedpnnlgefsdyptalfstfelflti
idgpanysvdlpfmycityaafaiiatllmlnlfiammgdtharvaqerdelwraqvvat
tvmlerkmprflwprsgicgyeyglgdrwflrvenhhdqnplrvlryveafkcsdkedgq
eqlsekrpstvesgmlsrasvafqtpslsrttsqssnshrgweilrrntlghlnlgldlg
egdgeevyhf

    Sequence, based on observed residues (ATOM records):
    >6o1uB (B:)
geqdweqyrdrvnmlqqerirdspllqaakendlrllkilllnqscdfqqrgavgetalh
vaalydnleaatllmeaapelakepalcepfvgqtalhiavmnqnlnlvrallargasvs
aratgaafrrsphnliyygehplsfaacvgseeivrlliehgadiraqdslgntvlhili
lqpnktfacqmynlllsydehsdhlqslelvpnhqgltpfklagvegntvmfqhlmqkrk
hvqwtcgpltstlydlteidswgeelsflelvvsskkrearqileqtpvkelvsfkwkky
grpyfcvlaslyilymicfttcciyrplklrddnrtdprditilqqkllqeayvthqdni
rlvgelvtvtgaviillleipdifrvgasryfgqtilggpfhviiityaslvlltmvmrl
tnmngevvplsfalvlgwcsvmyfargfqmlgpftimiqkmifgdlmrfcwlmavvilgf
asafhitfqtedpnnlgefsdyptalfstfelfltiidgpanysvdlpfmycityaafai
iatllmlnlfiammgdtharvaqerdelwraqvvattvmlerkmprflwprsgicgyeyg
lgdrwflrvenhhd

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6o1uC (C:)
mgacppkakgpwaqlqklliswpvgeqdweqyrdrvnmlqqerirdspllqaakendlrl
lkilllnqscdfqqrgavgetalhvaalydnleaatllmeaapelakepalcepfvgqta
lhiavmnqnlnlvrallargasvsaratgaafrrsphnliyygehplsfaacvgseeivr
lliehgadiraqdslgntvlhililqpnktfacqmynlllsydehsdhlqslelvpnhqg
ltpfklagvegntvmfqhlmqkrkhvqwtcgpltstlydlteidswgeelsflelvvssk
krearqileqtpvkelvsfkwkkygrpyfcvlaslyilymicfttcciyrplklrddnrt
dprditilqqkllqeayvthqdnirlvgelvtvtgaviillleipdifrvgasryfgqti
lggpfhviiityaslvlltmvmrltnmngevvplsfalvlgwcsvmyfargfqmlgpfti
miqkmifgdlmrfcwlmavvilgfasafhitfqtedpnnlgefsdyptalfstfelflti
idgpanysvdlpfmycityaafaiiatllmlnlfiammgdtharvaqerdelwraqvvat
tvmlerkmprflwprsgicgyeyglgdrwflrvenhhdqnplrvlryveafkcsdkedgq
eqlsekrpstvesgmlsrasvafqtpslsrttsqssnshrgweilrrntlghlnlgldlg
egdgeevyhf

    Sequence, based on observed residues (ATOM records):
    >6o1uC (C:)
geqdweqyrdrvnmlqqerirdspllqaakendlrllkilllnqscdfqqrgavgetalh
vaalydnleaatllmeaapelakepalcepfvgqtalhiavmnqnlnlvrallargasvs
aratgaafrrsphnliyygehplsfaacvgseeivrlliehgadiraqdslgntvlhili
lqpnktfacqmynlllsydehsdhlqslelvpnhqgltpfklagvegntvmfqhlmqkrk
hvqwtcgpltstlydlteidswgeelsflelvvsskkrearqileqtpvkelvsfkwkky
grpyfcvlaslyilymicfttcciyrplklrddnrtdprditilqqkllqeayvthqdni
rlvgelvtvtgaviillleipdifrvgasryfgqtilggpfhviiityaslvlltmvmrl
tnmngevvplsfalvlgwcsvmyfargfqmlgpftimiqkmifgdlmrfcwlmavvilgf
asafhitfqtedpnnlgefsdyptalfstfelfltiidgpanysvdlpfmycityaafai
iatllmlnlfiammgdtharvaqerdelwraqvvattvmlerkmprflwprsgicgyeyg
lgdrwflrvenhhd

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6o1uD (D:)
mgacppkakgpwaqlqklliswpvgeqdweqyrdrvnmlqqerirdspllqaakendlrl
lkilllnqscdfqqrgavgetalhvaalydnleaatllmeaapelakepalcepfvgqta
lhiavmnqnlnlvrallargasvsaratgaafrrsphnliyygehplsfaacvgseeivr
lliehgadiraqdslgntvlhililqpnktfacqmynlllsydehsdhlqslelvpnhqg
ltpfklagvegntvmfqhlmqkrkhvqwtcgpltstlydlteidswgeelsflelvvssk
krearqileqtpvkelvsfkwkkygrpyfcvlaslyilymicfttcciyrplklrddnrt
dprditilqqkllqeayvthqdnirlvgelvtvtgaviillleipdifrvgasryfgqti
lggpfhviiityaslvlltmvmrltnmngevvplsfalvlgwcsvmyfargfqmlgpfti
miqkmifgdlmrfcwlmavvilgfasafhitfqtedpnnlgefsdyptalfstfelflti
idgpanysvdlpfmycityaafaiiatllmlnlfiammgdtharvaqerdelwraqvvat
tvmlerkmprflwprsgicgyeyglgdrwflrvenhhdqnplrvlryveafkcsdkedgq
eqlsekrpstvesgmlsrasvafqtpslsrttsqssnshrgweilrrntlghlnlgldlg
egdgeevyhf

    Sequence, based on observed residues (ATOM records):
    >6o1uD (D:)
geqdweqyrdrvnmlqqerirdspllqaakendlrllkilllnqscdfqqrgavgetalh
vaalydnleaatllmeaapelakepalcepfvgqtalhiavmnqnlnlvrallargasvs
aratgaafrrsphnliyygehplsfaacvgseeivrlliehgadiraqdslgntvlhili
lqpnktfacqmynlllsydehsdhlqslelvpnhqgltpfklagvegntvmfqhlmqkrk
hvqwtcgpltstlydlteidswgeelsflelvvsskkrearqileqtpvkelvsfkwkky
grpyfcvlaslyilymicfttcciyrplklrddnrtdprditilqqkllqeayvthqdni
rlvgelvtvtgaviillleipdifrvgasryfgqtilggpfhviiityaslvlltmvmrl
tnmngevvplsfalvlgwcsvmyfargfqmlgpftimiqkmifgdlmrfcwlmavvilgf
asafhitfqtedpnnlgefsdyptalfstfelfltiidgpanysvdlpfmycityaafai
iatllmlnlfiammgdtharvaqerdelwraqvvattvmlerkmprflwprsgicgyeyg
lgdrwflrvenhhd