PDB entry 6o1h
View 6o1h on RCSB PDB site
Description: Tryptophan synthase Q114A mutant in complex with N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site, cesium ion at the metal coordination site, and 2-aminophenol quinonoid at the enzyme beta site
Class: lyase
Keywords: Tryptophan synthase, mutant Q114A, lyase-inhibitor, protein complex, Salmonella, LYASE
Deposited on
2019-02-19, released
2020-02-19
The last revision prior to the SCOPe 2.08 freeze date was dated
2020-02-19, with a file datestamp of
2020-02-14.
Experiment type: XRAY
Resolution: 1.64 Å
R-factor: N/A
AEROSPACI score: 0.42
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: tryptophan synthase alpha chain
Species: Salmonella typhimurium [TaxId:90371]
Gene: trpA, DD95_04145
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d6o1ha_ - Chain 'B':
Compound: tryptophan synthase beta chain
Species: Salmonella typhimurium [TaxId:90371]
Gene: trpB, STM1726
Database cross-references and differences (RAF-indexed):
- Uniprot P0A2K1 (0-394)
- engineered mutation (112)
Domains in SCOPe 2.08: d6o1hb_ - Heterogens: DMS, F9F, CS, CL, HVK, 1D0, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>6o1hA (A:)
meryenlfaqlndrregafvpfvtlgdpgieqslkiidtlidagadalelgvpfsdplad
gptiqnanlrafaagvtpaqcfemlalirekhptipigllmyanlvfnngidafyarceq
vgvdsvlvadvpveesapfrqaalrhniapificppnadddllrqvasygrgytyllsrs
gvtgaenrgalplhhlieklkeyhaapalqgfgisspeqvsaavragaagaisgsaivki
ieknlaspkqmlaelrsfvsamkaasra
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>6o1hB (B:)
ttllnpyfgefggmyvpqilmpalnqleeafvsaqkdpefqaqfadllknyagrptaltk
cqnitagtrttlylkredllhggahktnqvlgqallakrmgkseiiaetgagahgvasal
asallglkcriymgakdverqspnvfrmrlmgaevipvhsgsatlkdacnealrdwsgsy
etahymlgtaagphpyptivrefqrmigeetkaqildkegrlpdaviacvgggsnaigmf
adfindtsvgligvepgghgietgehgaplkhgrvgiyfgmkapmmqtadgqieesysis
agldfpsvgpqhaylnsigradyvsitddealeafktlcrhegiipalesshalahalkm
mreqpekeqllvvnlsgrgdkdiftvhdilkarge