PDB entry 6nxz
View 6nxz on RCSB PDB site
Description: Crystal structure of trimethoprim-resistant type II dihydrofolate reductase in complex with a bisbenzimidazole inhibitor
Class: oxidoreductase
Keywords: antibiotic resistance; selective inhibitor; R67 DHFR; SH3-like barrel, ANTIBIOTIC, OXIDOREDUCTASE
Deposited on
2019-02-10, released
2019-05-29
The last revision prior to the SCOPe 2.08 freeze date was dated
2020-01-08, with a file datestamp of
2020-01-03.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: N/A
AEROSPACI score: 0.39
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Dihydrofolate reductase type 2
Species: Escherichia coli [TaxId:562]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d6nxza_ - Heterogens: D49, MRD, PO4, HOH