PDB entry 6nvh

View 6nvh on RCSB PDB site
Description: FGFR4 complex with N-(2-((5-((2,6-dichloro-3,5-dimethoxybenzyl)oxy)pyrimidin-2-yl)amino)-3-methylphenyl)acrylamide
Class: transferase/transferase inhibitor
Keywords: TRANSFERASE-TRANSFERASE INHIBITOR complex, TRANSFERASE
Deposited on 2019-02-05, released 2019-07-10
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-08-28, with a file datestamp of 2019-08-23.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Fibroblast growth factor receptor 4
    Species: Homo sapiens [TaxId:9606]
    Gene: FGFR4, JTK2, TKF
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6nvha_
  • Heterogens: SO4, XL6, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6nvhA (A:)
mvsldlpldplwefprdrlvlgkplgegcfgqvvraeafgmdparpdqastvavkmlkdn
asdkdladlvsemevmkligrhkniinllgvctqegplyvivecaakgnlreflrarrpp
gssegplsfpvlvscayqvargmqylesrkcihrdlaarnvlvtednvmkiadfglargv
hhidyykktsngrlpvkwmapealfdrvythqsdvwsfgillweiftlggspypgipvee
lfsllreghrmdrpphcppelyglmrecwhaapsqrptfkqlvealdkvllavshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6nvhA (A:)
dlpldplwefprdrlvlgkplgegqvvraeafgmdparpdqastvavkmlkdnasdkdla
dlvsemevmkligrhkniinllgvctqegplyvivecaakgnlreflrarrppgssegpl
sfpvlvscayqvargmqylesrkcihrdlaarnvlvtednvmkiadfglarlpvkwmape
alfdrvythqsdvwsfgillweiftlggspypgipveelfsllreghrmdrpphcppely
glmrecwhaapsqrptfkqlvealdkvllav